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Author Details

Fiona Grueninger
Roche Pharma Research and Early Development (pRED)
1996
13
11
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
33891876Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.Cell2021
28657418Chemically-defined camelid antibody bioconjugate for the magnetic resonance imaging of Alzheimer's disease.MAbs2017
28642233Sembragiline: A Novel, Selective Monoamine Oxidase Type B Inhibitor for the Treatment of Alzheimer's Disease.J Pharmacol Exp Ther2017
27671875Camelid single-domain antibodies: A versatile tool for in vivo imaging of extracellular and intracellular brain targets.J Control Release2016
24050961Intercellular transfer of tau aggregates and spreading of tau pathology: Implications for therapeutic strategies.Neuropharmacology2014
24517102Lesion of the subiculum reduces the spread of amyloid beta pathology to interconnected brain regions in a mouse model of Alzheimer's disease.Acta Neuropathol Commun2014
24337498Neuropathological characterization of two siblings carrying the MAPT S305S mutation demonstrates features resembling argyrophilic grain disease.Acta Neuropathol2014
21638028Novel screening cascade identifies MKK4 as key kinase regulating Tau phosphorylation at Ser422.Mol Cell Biochem2011
19781645Phosphorylation of Tau at S422 is enhanced by Abeta in TauPS2APP triple transgenic mice.Neurobiol Dis2010
9561248Studies on plasmepsins I and II from the malarial parasite Plasmodium falciparum and their exploitation as drug targets.Adv Exp Med Biol1998
9332717Expression and characterization of human beta-secretase candidates metalloendopeptidase MP78 and cathepsin D in beta APP-overexpressing cells.Brain Res Mol Brain Res1997
9119023Expression and characterisation of plasmepsin I from Plasmodium falciparum.Eur J Biochem1997
8976570Deglycosylation of proteins for crystallization using recombinant fusion protein glycosidases.Protein Sci1996
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Collaborators

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University of California San Francisco
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Harvard Medical School
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Albert Einstein College of Medicine
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Columbia University Medical Center, New York State Psychiatric Institute
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and Institute for Aging Studies, Albert Einstein College of Medicine
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Albert Einstein College of Medicine
Co-authored papers 1
Albert Einstein College of Medicine
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Albert Einstein College of Medicine, USA Institute for Aging Studies
Co-authored papers 1
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 1
Albert Einstein College of Medicine
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J. David Gladstone Institutes
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University College London, UK Dementia Research Institute
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