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Author Details

Milan Mrksich
Northwestern University
1992
196
62
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35129954Efficient Enzymatic Incorporation of Dehydroalanine Based on SAMDI-Assisted Identification of Optimized Tags for OspF/SpvC.ACS Chem Biol2022
35650184Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria.Nat Commun2022
35500232High-Throughput Microfluidics Platform for Intracellular Delivery and Sampling of Biomolecules from Live Cells.ACS Nano2022
36064958Tyrosine phosphatase activity is restricted by basic charge substituting mutation of substrates.Sci Rep2022
35881504Scanning Transmission Electron Microscopy in a Scanning Electron Microscope for the High-Throughput Imaging of Biological Assemblies.Biomacromolecules2022
36151248Surface potential modulation as a tool for mitigating challenges in SERS-based microneedle sensors.Sci Rep2022
34890480Characterizing Enzyme Cooperativity with Imaging SAMDI-MS.Chemistry2022
33301672Synthetic Tuning of Domain Stoichiometry in Nanobody-Enzyme Megamolecules.Bioconjug Chem2021
34934149Morphological features of single cells enable accurate automated classification of cancer from non-cancer cell lines.Sci Rep2021
34903884NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding.Nat Metab2021
34729416Storing and Reading Information in Mixtures of Fluorescent Molecules.ACS Cent Sci2021
34713526Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly.Chemistry2021
33979120Synthesis, Characterization, and Simulation of Four-Armed Megamolecules.Biomacromolecules2021
33314922Exploring the Ligand Preferences of the PHD1 Domain of Histone Demethylase KDM5A Reveals Tolerance for Modifications of the Q5 Residue of Histone 3.ACS Chem Biol2021
32452612Temporal Sampling of Enzymes from Live Cells by Localized Electroporation and Quantification of Activity by SAMDI Mass Spectrometry.Small2020
31691395Using Peptide Arrays to Profile Phosphatase Activity in Cell Lysates.Chemistry2020
32105451Solid-Phase Synthesis of Megamolecules.J Am Chem Soc2020
31854989High-Throughput Synthesis and Analysis of Intact Glycoproteins Using SAMDI-MS.Anal Chem2020
33049755Computational planning of the synthesis of complex natural products.Nature2020
33174742High Throughput Screening with SAMDI Mass Spectrometry for Directed Evolution.J Am Chem Soc2020
32570704Role of Lipopolysaccharide in Protecting OmpT from Autoproteolysis during In Vitro Refolding.Biomolecules2020
32706963Design and Synthesis of Megamolecule Mimics of a Therapeutic Antibody.J Am Chem Soc2020
32618102Outer-Membrane Protease (OmpT) Based E. coli Sensing with Anionic Polythiophene and Unlabeled Peptide Substrate.Angew Chem Int Ed Engl2020
32123732Sequential Glycosylation of Proteins with Substrate-Specific <i>N</i>-Glycosyltransferases.ACS Cent Sci2020
32325029Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells.Mol Cell2020
32297889A high-throughput SAMDI-mass spectrometry assay for isocitrate dehydrogenase 1.Analyst2020
32482866High-throughput photocapture approach for reaction discovery.Proc Natl Acad Sci U S A2020
30817132Using Peptide Arrays To Discover the Sequence-Specific Acetylation of the Histidine-Tyrosine Dyad.Biochemistry2019
31776339A cell-free biosynthesis platform for modular construction of protein glycosylation pathways.Nat Commun2019
31532622Subcellular Control over Focal Adhesion Anisotropy, Independent of Cell Morphology, Dictates Stem Cell Fate.ACS Nano2019
31183410High-throughput mapping of CoA metabolites by SAMDI-MS to optimize the cell-free biosynthesis of HMG-CoA.Sci Adv2019
31553163Profiling Protein Tyrosine Phosphatase Specificity with Self-Assembled Monolayers for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry and Peptide Arrays.ACS Comb Sci2019
31545611Plasmonic Microneedle Arrays for in Situ Sensing with Surface-Enhanced Raman Spectroscopy (SERS).Nano Lett2019
31536703Label-Free Assay of Protein Tyrosine Phosphatase Activity in Single Cells.Anal Chem2019
30952978Exploration of the nanomedicine-design space with high-throughput screening and machine learning.Nat Biomed Eng2019
30943037Sequential Photoactivation of Self-Assembled Monolayers to Direct Cell Adhesion and Migration.Langmuir2019
30937376Using Microfluidics and Imaging SAMDI-MS To Characterize Reaction Kinetics.ACS Cent Sci2019
31139727Storage of Information Using Small Organic Molecules.ACS Cent Sci2019
29135227Peptide Arrays: Development and Application.Anal Chem2018
30002445Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.Nat Commun2018
29891655Potent laminin-inspired antioxidant regenerative dressing accelerates wound healing in diabetes.Proc Natl Acad Sci U S A2018
29971942An Immobilized Enzyme Reactor for Spatiotemporal Control over Reaction Products.Small2018
30127449Author Correction: Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.Nat Commun2018
30149867Combining SAMDI Mass Spectrometry and Peptide Arrays to Profile Phosphatase Activities.Methods Enzymol2018
29901996Traceless Immobilization of Analytes for High-Throughput Experiments with SAMDI Mass Spectrometry.J Am Chem Soc2018
30257085High-Throughput Enzyme Kinetics with 3D Microfluidics and Imaging SAMDI Mass Spectrometry.Anal Chem2018
31011283Dynamic Substrates for Cell Biology.Curr Opin Colloid Interface Sci2018
30379516Photoactivatable Reaction for Covalent Nanoscale Patterning of Multiple Proteins.ACS Appl Mater Interfaces2018
30375862Long-Range Energy Transfer in Protein Megamolecules.J Am Chem Soc2018
29443976How many human proteoforms are there?Nat Chem Biol2018
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Collaborators

Michael C Jewett
Northwestern University
Co-authored papers 9
Peter B Dervan
Co-authored papers 6
Kristin G Beaumont
Co-authored papers 4
Vinayak P Dravid
Co-authored papers 4
Carolyn R Bertozzi
Stanford University
Co-authored papers 3
Neda Bagheri
University of Washington
Co-authored papers 3
Christopher B Newgard
Duke Molecular Physiology Institute
Co-authored papers 2
Alan J Wolfe
Stritch School of Medicine, Loyola University Chicago
Co-authored papers 2
Bradford W Gibson
The Buck Institute for Research on Aging
Co-authored papers 2
Birgit Schilling
Buck Institute for Research on Aging
Co-authored papers 2
Steven M Patrie
Northwestern University
Co-authored papers 2
Nathan A Yates
University of Pittsburgh School of Medicine
Co-authored papers 1
James J Pesavento
Saint Mary's College of California
Co-authored papers 1
Therese Wohlschlager
University of Salzburg
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Ole N Jensen
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 1
Nicolas L Young
Baylor College of Medicine, USA Center for Precision Environmental Health
Co-authored papers 1
James E Longbotham
University of California San Francisco
Co-authored papers 1
Danica Galoni?? Fujimori
University of California San Francisco
Co-authored papers 1
Mark S Baker
Macquarie University
Co-authored papers 1
Fatima S Ugur
University of California San Francisco
Co-authored papers 1
Sharon J Pitteri
Stanford University
Co-authored papers 1
Jeremy Gunawardena
Harvard Medical School
Co-authored papers 1
David R Walt
Brigham and Women's Hospital
Co-authored papers 1
Gregory A Voth
Co-authored papers 1
Alexander R Ivanov
Barnett Institute of Chemical and Biological Analysis, Northeastern University
Co-authored papers 1
Michael J MacCoss
University of Washington
Co-authored papers 1
Bin Zhang
Graduate School of Medicine, The University of Tokyo
Co-authored papers 1
Brian Meckes
Co-authored papers 1
Gang Fang
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Release 1.2