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Author Details

Pedro Beltrao
Institute of Molecular Systems Biology, ETH Zurich
2003
75
36
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36688815Pan-Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival.Mol Syst Biol2023
37738970SARS-CoV-2 variants evolve convergent strategies to remodel the host response.Cell2023
37647632The effects of pathogenic and likely pathogenic variants for inherited hemostasis disorders in 140â¿¿214 UK Biobank participants.Blood2023
37386082A human proteogenomic-cellular framework identifies KIF5A as a modulator of astrocyte process integrity with relevance to ALS.Commun Biol2023
37161576High-throughput deep learning variant effect prediction with Sequence UNET.Genome Biol2023
36515990Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization.J Cell Biol2023
36690744Towards a structurally resolved human protein interaction network.Nat Struct Mol Biol2023
34663920High-throughput functional characterization of protein phosphorylation sites in yeast.Nat Biotechnol2022
35864335Systematic discovery of biomolecular condensate-specific protein phosphorylation.Nat Chem Biol2022
36087372Network analysis of genome-wide association studies for drug target prioritisation.Curr Opin Chem Biol2022
34942634Evolution of enhanced innate immune evasion by SARS-CoV-2.Nature2022
35332335Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2.Nature2022
33440154Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases.Cell Rep2021
33590968SARS-CoV-2 infection remodels the host protein thermal stability landscape.Mol Syst Biol2021
33589840Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes.Nat Genet2021
33637963Author Correction: Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer's disease risk genes.Nat Genet2021
33837377Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19.Nat Med2021
34127972Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant.bioRxiv2021
34292650Exploring amino acid functions in a deep mutational landscape.Mol Syst Biol2021
34010657Copy number aberrations drive kinase rewiring, leading to genetic vulnerabilities in cancer.Cell Rep2021
34260159Individual COVID-19 disease trajectories revealed by plasma proteomics.EMBO Mol Med2021
32483290Unraveling tumor-immune heterogeneity in advanced ovarian cancer uncovers immunogenic effect of chemotherapy.Nat Genet2020
33060197Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.Science2020
33112851Major role of iron uptake systems in the intrinsic extra-intestinal virulence of the genus Escherichia revealed by a genome-wide association study.PLoS Genet2020
32645325The Global Phosphorylation Landscape of SARS-CoV-2 Infection.Cell2020
32437683Prediction of Signed Protein Kinase Regulatory Circuits.Cell Syst2020
32353859A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.Nature2020
32514074Spatiotemporal proteomics uncovers cathepsin-dependent macrophage cell death during Salmonella infection.Nat Microbiol2020
30397019iProteinDB: An Integrative Database of <i>Drosophila</i> Post-translational Modifications.G3 (Bethesda)2019
31885205The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae.Mol Syst Biol2019
31239291Multi-omics Characterization of Interaction-mediated Control of Human Protein Abundance levels.Mol Cell Proteomics2019
31233486Evolution of protein kinase substrate recognition at the active site.PLoS Biol2019
31451789Selective deployment of transcription factor paralogs with submaximal strength facilitates gene regulation in the immune system.Nat Immunol2019
31036831Conserved phosphorylation hotspots in eukaryotic protein domain families.Nat Commun2019
29316484Evolution, dynamics and dysregulation of kinase signalling.Curr Opin Struct Biol2018
30072490Reconstructing phosphorylation signalling networks from quantitative phosphoproteomic data.Essays Biochem2018
30573687A resource of variant effect predictions of single nucleotide variants in model organisms.Mol Syst Biol2018
28072816Systematic Analysis of Transcriptional and Post-transcriptional Regulation of Metabolism in Yeast.PLoS Comput Biol2017
28200105Benchmarking substrate-based kinase activity inference using phosphoproteomic data.Bioinformatics2017
28287266Identifications of Putative PKA Substrates with Quantitative Phosphoproteomics and Primary-Sequence-Based Scoring.J Proteome Res2017
29032074Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer.Cell Syst2017
29280730Phenotype inference in an <i>Escherichia coli</i> strain panel.Elife2017
29141230Sub-minute Phosphoregulation of Cell Cycle Systems during Plasmodium Gamete Formation.Cell Rep2017
28854368Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.Cell Rep2017
27738172Evolution of protein phosphorylation across 18 fungal species.Science2016
26572964Uncovering Phosphorylation-Based Specificities through Functional Interaction Networks.Mol Cell Proteomics2016
27909043An atlas of human kinase regulation.Mol Syst Biol2016
25814556Kinase-two-hybrid: towards the conditional interactome.Mol Syst Biol2015
26312481Prediction of Functionally Important Phospho-Regulatory Events in Xenopus laevis Oocytes.PLoS Comput Biol2015
25888283Differential genetic interactions of yeast stress response MAPK pathways.Mol Syst Biol2015
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Collaborators

Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 20
Danish Memon
European Bioinformatics Institute
Co-authored papers 14
Inigo Barrio-Hernandez
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 11
Danielle L Swaney
J. David Gladstone Institutes
Co-authored papers 10
Kevan M Shokat
University of California San Francisco
Co-authored papers 9
Athanasios Typas
University of California san francisco
Co-authored papers 8
Jyoti Batra
J. David Gladstone Institutes
Co-authored papers 7
Mehdi Bouhaddou
J. David Gladstone Institutes
Co-authored papers 7
Alistair S Dunham
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 7
Margaret Soucheray
J. David Gladstone Institutes
Co-authored papers 7
Kirsten Obernier (CM4AI)
University of California San Francisco
Co-authored papers 7
Omar Wagih
European Bioinformatics Institute
Co-authored papers 6
Adolfo Garc??a-Sastre
Icahn School of Medicine at Mount Sinai
Co-authored papers 6
Joseph B Hiatt
Fred Hutchinson Cancer Center
Co-authored papers 6
Julio Saez-Rodriguez
Institute of Computational Biomedicine, Heidelberg University
Co-authored papers 6
Kliment A Verba
University of California, University of California San Francisco
Co-authored papers 6
Kris M White
Quantitative Biosciences Institute (QBI) Coronavirus Research Group (QCRG)
Co-authored papers 6
Hannes Braberg
University of California San Francisco
Co-authored papers 5
Manisha Ummadi
University of California, San Francisco
Co-authored papers 5
Natalia Jura
Cardiovascular Research Institute, University of California San Francisco
Co-authored papers 5
Alicia L Richards
University of Wisconsin-Madison
Co-authored papers 5
Jiewei Xu
Quantitative Biosciences Institute (QBI), University of California san francisco
Co-authored papers 5
Jane Turner
University College London
Co-authored papers 4
Claudia Hernandez-Armenta
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 4
Judit Vill??n
University of Washington
Co-authored papers 4
Adrian Pelin
University of Ottawa
Co-authored papers 4
Lisa Miorin
Icahn School of Medicine at Mount Sinai
Co-authored papers 4
Greg J Towers
University College London
Co-authored papers 4
Matthew V X Whelan
University College London
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Ruth H??ttenhain
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Release 1.2