Author details

Full Name

Zhining Wen

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36658410	A pilot study on identifying gene signatures as markers for predicting patient response to antiseizure medications.		2023
37047744	Unraveling Structural Alerts in Marketed Drugs for Improving Adverse Outcome Pathway Framework of Drug-Induced QT Prolongation.		2023
34718206	Drug-induced QT Prolongation Atlas (DIQTA) for enhancing cardiotoxicity management.	Drug Discovery Today	2022
35281912	Structure-Activity Relationship (SAR) Model for Predicting Teratogenic Risk of Antiseizure Medications in Pregnancy by Using Support Vector Machine.	Frontiers in Pharmacology	2022
35186787	Raman Spectroscopy: A Potential Diagnostic Tool for Oral Diseases.	Frontiers in Cellular and Infection Microbiology	2022
33393765	Quantitative Structure-Activity Relationship (QSAR) Model for the Severity Prediction of Drug-Induced Rhabdomyolysis by Using Random Forest.	Chemical Research in Toxicology	2021
34163355	Comparative Analysis for the Performance of Long-Read-Based Structural Variation Detection Pipelines in Tandem Repeat Regions.	Frontiers in Pharmacology	2021
33986671	Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics.	Frontiers in Pharmacology	2021
33863366	A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency.	Genome Biol	2021
33863344	Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions.	Genome Biol	2021
32908867	Improving Model Performance on the Stratification of Breast Cancer Patients by Integrating Multiscale Genomic Features.	BioMed Research International	2020
32429941	Uncovering the prognostic gene signatures for the improvement of risk stratification in cancers by using deep learning algorithm coupled with wavelet transform.	BMC Bioinformatics	2020
31105557	Comparative Analysis for the Performance of Variant Calling Pipelines on Detecting the Mutations in Humans.	Frontiers in Pharmacology	2019
31695724	Transcriptome Analysis Identifies Piwi-Interacting RNAs as Prognostic Markers for Recurrence of Prostate Cancer.	Frontiers in Genetics	2019
31992983	Narrowing the Gap Between and Genetic Profiles by Deconvoluting Toxicogenomic Data .	Frontiers in Pharmacology	2019
29902520	Drug-Induced Rhabdomyolysis Atlas (DIRA) for idiosyncratic adverse drug reaction management.	Drug Discov Today	2019
29951521	Advancing Genomics for Drug Development and Safety Evaluation.	International Journal of Genomics	2018
35558583	Using accelerated molecular dynamics simulation to shed light on the mechanism of activation/deactivation upon mutations for CCR5.	RSC Advances	2018
28110245	Bipartite network analysis reveals metabolic gene expression profiles that are highly associated with the clinical outcomes of acute myeloid leukemia.		2017
28851270	Expression dynamics and relations with nearby genes of rat transposable elements across 11 organs, 4 developmental stages and both sexes.	BMC Genomics	2017
28831388	A New Network-Based Strategy for Predicting the Potential miRNA-mRNA Interactions in Tumorigenesis.	International Journal of Genomics	2017
29100309	Evaluating oral epithelial dysplasia classification system by near-infrared Raman spectroscopy.	Oncotarget	2017
29297280	Mutation status coupled with RNA-sequencing data can efficiently identify important non-significantly mutated genes serving as diagnostic biomarkers of endometrial cancer.	BMC Bioinformatics	2017
27349736	A new strategy for exploring the hierarchical structure of cancers by adaptively partitioning functional modules from gene expression network.	Scientific Reports	2016
26501374	Comparative analysis of oncogenes identified by microarray and RNA-sequencing as biomarkers for clinical prognosis.	Biomarkers in Medicine	2015
26438216	Label-free blood serum detection by using surface-enhanced Raman spectroscopy and support vector machine for the preoperative diagnosis of parotid gland tumors.	BMC Cancer	2015
25106527	Genome-wide association study combined with biological context can reveal more disease-related SNPs altering microRNA target seed sites.	BMC Genomics	2014
24440656	Improving the prediction of chemotherapeutic sensitivity of tumors in breast cancer via optimizing the selection of candidate genes.		2014
25126556	Identifying the gene signatures from gene-pathway bipartite network guarantees the robust model performance on predicting the cancer prognosis.	BioMed Research International	2014
23703112	Utilization of gene expression signature for quality control of traditional Chinese medicine formula Si-Wu-Tang.	AAPS Journal	2013
23305139	Transcriptional profiling of Chinese medicinal formula Si-Wu-Tang on breast cancer cells reveals phytoestrogenic activity.	BMC Complementary and Alternative Medicine	2013
23627640	Investigating the concordance of Gene Ontology terms reveals the intra- and inter-platform reproducibility of enrichment analysis.	BMC Bioinformatics	2013
21761178	Effects of the position and manner of hydration on the stability of solvated N-methylacetamides and the strength of binding between N-methylacetamide and water clusters: a computational study.	Journal of Molecular Modeling	2012
21479702	Wavelet transform analysis of NMR structure ensembles to reveal internal fluctuations of enzymes.	Amino Acids	2012
21223604	Predicting disease-associated substitution of a single amino acid by analyzing residue interactions.	BMC Bioinformatics	2011
21439894	Discrimination of parotid neoplasms from the normal parotid gland by use of Raman spectroscopy and support vector machine.	Oral Oncology	2011
20691775	Changes in gene expression after phencyclidine administration in developing rats: a potential animal model for schizophrenia.	International Journal of Developmental Neuroscience	2011
21468322	Novel feature for catalytic protein residues reflecting interactions with other residues.	PLoS ONE	2011
21464939	Discovery of molecular mechanisms of traditional Chinese medicinal formula Si-Wu-Tang using gene expression microarray and connectivity map.	PLoS One	2011
20153740	Abnormal gene expression in cerebellum of Npc1-/- mice during postnatal development.	Brain Research	2010
20946593	Evaluation of gene expression data generated from expired Affymetrix GeneChipÂ® microarrays using MAQC reference RNA samples.	BMC Bioinformatics	2010
20676074	The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.	Nat Biotechnol	2010
20337078	[Near infrared Raman spectral character and diagnostic value of squamous cell carcinoma of oral mucosa].	Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology	2010
20015389	In silico method for systematic analysis of feature importance in microRNA-mRNA interactions.	BMC Bioinformatics	2009
19811677	Microarray platform consistency is revealed by biologically functional analysis of gene expression profiles.	BMC Bioinformatics	2009
18635288	Effects of neighboring sequence environment in predicting cleavage sites of signal peptides.	Peptides	2008
17520325	Using pseudo amino acid composition to predict transmembrane regions in protein: cellular automata and Lempel-Ziv complexity.	Amino Acids	2008
18390576	Using support vector machine combined with auto covariance to predict protein-protein interactions from protein sequences.	Nucleic Acids Research	2008
16729188	Delaunay triangulation with partial least squares projection to latent structures: a model for G-protein coupled receptors classification and fast structure recognition.	Amino Acids	2007
16773242	Classifying G protein-coupled receptors and nuclear receptors on the basis of protein power spectrum from fast Fourier transform.	Amino Acids	2006