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Author Details

Richard T Kloos
Veracyte Inc.
1995
112
45
PMIDPaper TitleJournal TitlePublished Year
36470585Real-World Performance of the Afirma Genomic Sequencing Classifier (GSC)-A Meta-analysis.J Clin Endocrinol Metab2023
37544986Combined Afirma Genomic Sequencing Classifier and TERT promoter mutation detection in molecular assessment of Bethesda III-VI thyroid nodules.Cancer Cytopathol2023
36675685Maximizing Small Biopsy Patient Samples: Unified RNA-Seq Platform Assessment of over 120,000 Patient Biopsies.J Pers Med2022
35793115Preoperative Identification of Medullary Thyroid Carcinoma (MTC): Clinical Validation of the Afirma MTC RNA-Sequencing Classifier.Thyroid2022
36619548Risk of malignancy in cytologically indeterminate thyroid nodules harboring thyroid stimulating hormone receptor mutations.Front Endocrinol (Lausanne)2022
33269526Limitations of preoperative cytology for medullary thyroid cancer: Proposal for improved preoperative diagnosis for optimal initial medullary thyroid carcinoma specific surgery.Head Neck2021
33655886Pathologic Features Associated With Molecular Subtypes of Well-Differentiated Thyroid Cancer.Endocr Pract2021
33789450A Joint Statement from the American Thyroid Association, the European Association of Nuclear Medicine, the European Thyroid Association, the Society of Nuclear Medicine and Molecular Imaging on Current Diagnostic and Theranostic Approaches in the Management of Thyroid Cancer.Thyroid2021
34009369Afirma Genomic Sequencing Classifier and Xpression Atlas Molecular Findings in Consecutive Bethesda III-VI Thyroid Nodules.J Clin Endocrinol Metab2021
32543766The Afirma Xpression Atlas for thyroid nodules and thyroid cancer metastases: Insights to inform clinical decision-making from a fine-needle aspiration sample.Cancer Cytopathol2020
31917394Concerns About Methodology in Study of Thyroid Nodule Gene Expression Classifier.JAMA Otolaryngol Head Neck Surg2020
32123131Appropriate Use Criteria for Nuclear Medicine in the Evaluation and Treatment of Differentiated Thyroid Cancer.J Nucl Med2020
30820785Long-Term Efficacy of Lymph Node Reoperation for Persistent Papillary Thyroid Cancer: 13-Year Follow-Up.Ann Surg Oncol2019
31469053Molecular Variants and Their Risks for Malignancy in Cytologically Indeterminate Thyroid Nodules.Thyroid2019
31572297Analytical and Clinical Validation of Expressed Variants and Fusions From the Whole Transcriptome of Thyroid FNA Samples.Front Endocrinol (Lausanne)2019
31333584Analytical Verification Performance of Afirma Genomic Sequencing Classifier in the Diagnosis of Cytologically Indeterminate Thyroid Nodules.Front Endocrinol (Lausanne)2019
31017745Extending expressed RNA genomics from surgical decision making for cytologically indeterminate thyroid nodules to targeting therapies for metastatic thyroid cancer.Cancer Cytopathol2019
30952205Identification of Hürthle cell cancers: solving a clinical challenge with genomic sequencing and a trio of machine learning algorithms.BMC Syst Biol2019
28755389No calcitonin change in a person taking dulaglutide diagnosed with pre-existing medullary thyroid cancer.Diabet Med2018
29799911Performance of a Genomic Sequencing Classifier for the Preoperative Diagnosis of Cytologically Indeterminate Thyroid Nodules.JAMA Surg2018
29665745Heterogeneity in Positive Predictive Value of RAS Mutations in Cytologically Indeterminate Thyroid Nodules.Thyroid2018
28117288Molecular Profiling of Thyroid Nodules: Current Role for the Afirma Gene Expression Classifier on Clinical Decision Making.Mol Imaging Radionucl Ther2017
26973059Impact of a gene expression classifier on the long-term management of patients with cytologically indeterminate thyroid nodules.Curr Med Res Opin2016
27605259Analytical Performance of a Gene Expression Classifier for Medullary Thyroid Carcinoma.Thyroid2016
27604949Multifocality in Sporadic Medullary Thyroid Carcinoma: An International Multicenter Study.Thyroid2016
27124249Gene Expression Classifier Testing and the Surgical Decision-Making Process for Patients With Thyroid Nodules.JAMA Otolaryngol Head Neck Surg2016
27533304Risk Factors of <sup>131</sup>I-Induced Salivary Gland Damage in Thyroid Cancer Patients.J Clin Endocrinol Metab2016
26992356A Genomic Alternative to Identify Medullary Thyroid Cancer Preoperatively in Thyroid Nodules with Indeterminate Cytology.Thyroid2016
26818556The diagnostic application of RNA sequencing in patients with thyroid cancer: an analysis of 851 variants and 133 fusions in 524 genes.BMC Bioinformatics2016
25592597Machine learning from concept to clinic: reliable detection of BRAF V600E DNA mutations in thyroid nodules using high-dimensional RNA expression data.Pac Symp Biocomput2015
26335722Response to "American Thyroid Association Statement on Surgical Application of Molecular Profiling for Thyroid Nodules: Current Impact on Perioperative Decision Making".Thyroid2015
25694510Germline and somatic SDHx alterations in apparently sporadic differentiated thyroid cancer.Endocr Relat Cancer2015
24902006Overview and management of dermatologic events associated with targeted therapies for medullary thyroid cancer.Thyroid2014
25041959Clinical diagnostic gene expression thyroid testing.Otolaryngol Clin North Am2014
22978687In thyroidectomized patients with thyroid cancer, a serum thyrotropin of 30⿿μU/mL after thyroxine withdrawal is not always adequate for detecting an elevated stimulated serum thyroglobulin.Thyroid2013
23964768Ernest L. Mazzaferri, MD, MACP (1936-2013).Thyroid2013
24026318A prospective assessment defining the limitations of thyroid nodule pathologic evaluation.Ann Intern Med2013
23733893Clinical practice guideline: improving voice outcomes after thyroid surgery.Otolaryngol Head Neck Surg2013
23757627Fine needle aspiration and medullary thyroid carcinoma: the risk of inadequate preoperative evaluation and initial surgery when relying upon FNAB cytology alone.Endocr Pract2013
23476074Does addition of BRAF V600E mutation testing modify sensitivity or specificity of the Afirma Gene Expression Classifier in cytologically indeterminate thyroid nodules?J Clin Endocrinol Metab2013
23525286Molecular markers in the diagnosis of thyroid nodules.Arq Bras Endocrinol Metabol2013
23539728SRGAP1 is a candidate gene for papillary thyroid carcinoma susceptibility.J Clin Endocrinol Metab2013
22934541Predicting hypothyroidism from the Whickham Survey.Clin Endocrinol (Oxf)2013
22136206MicroRNA signature in thyroid fine needle aspiration cytology applied to "atypia of undetermined significance" cases.Thyroid2012
247829912012 European thyroid association guidelines for metastatic medullary thyroid cancer urge restrained use of novel kinase inhibitors.Eur Thyroid J2012
22731672Preoperative diagnosis of benign thyroid nodules with indeterminate cytology.N Engl J Med2012
22540327Micro-single-photon emission computed tomography image acquisition and quantification of sodium-iodide symporter-mediated radionuclide accumulation in mouse thyroid and salivary glands.Thyroid2012
22313454American Thyroid Association design and feasibility of a prospective randomized controlled trial of prophylactic central lymph node dissection for papillary thyroid carcinoma.Thyroid2012
22267200Discovery of common variants associated with low TSH levels and thyroid cancer risk.Nat Genet2012
20943788The prevalence of occult medullary thyroid carcinoma at autopsy.J Clin Endocrinol Metab2011
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Collaborators

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Biological and Chemical Research Centre, University of Warsaw
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Dana-Farber Cancer Institute, Harvard Medical School
Co-authored papers 2
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Emory University
Co-authored papers 1
Yale Center for Analytical Sciences, Yale School of Public Health
Co-authored papers 1
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Hollings Cancer Center, Medical University of South Carolina
Co-authored papers 1
M. Sklodowska-Curie National Research Institute of Oncology
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Research Institute at Nationwide Childrens Hospital, University of Iowa
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Maria Sklodowska-Curie Institute - Oncology Centre
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Medical University of Warsaw
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The Ohio State University
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University of Iceland
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