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Author Details

Xun Zhao
1994
15
14
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
26882000Correction to The 2.5 ÿ Crystal Structure of the SIRT1 Catalytic Domain Bound to Nicotinamide Adenine Dinucleotide (NAD(+)) and an Indole (EX527 Analogue) Reveals a Novel Mechanism of Histone Deacetylase Inhibition.J Med Chem2016
23311358The 2.5 ÿ crystal structure of the SIRT1 catalytic domain bound to nicotinamide adenine dinucleotide (NAD+) and an indole (EX527 analogue) reveals a novel mechanism of histone deacetylase inhibition.J Med Chem2013
19944699Structure and dynamics of NBD1 from CFTR characterized using crystallography and hydrogen/deuterium exchange mass spectrometry.J Mol Biol2010
20687163Integrated biophysical studies implicate partial unfolding of NBD1 of CFTR in the molecular pathogenesis of F508del cystic fibrosis.Protein Sci2010
20687133Thermal unfolding studies show the disease causing F508del mutation in CFTR thermodynamically destabilizes nucleotide-binding domain 1.Protein Sci2010
20737437Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.Proteins2010
20150177Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.Protein Eng Des Sel2010
15528182Impact of the deltaF508 mutation in first nucleotide-binding domain of human cystic fibrosis transmembrane conductance regulator on domain folding and structure.J Biol Chem2005
14685259Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator.EMBO J2004
11780146Structure of the Bcr-Abl oncoprotein oligomerization domain.Nat Struct Biol2002
11106388Structural characterization of the human respiratory syncytial virus fusion protein core.Proc Natl Acad Sci U S A2000
9860950Interaction of the Hsp70 molecular chaperone, DnaK, with its cochaperone DnaJ.Proc Natl Acad Sci U S A1998
8658133Structural analysis of substrate binding by the molecular chaperone DnaK.Science1996
8855230Mutations in the C-terminal fragment of DnaK affecting peptide binding.Proc Natl Acad Sci U S A1996
8289323Specificity of DnaK-peptide binding.J Mol Biol1994
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Collaborators

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Eli Lilly and Co.
Co-authored papers 4
New York SGX Research Center for Structural Genomics
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Lilly Research Laboratories
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Columbia University
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The State University of New Jersey
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Beth Israel Deaconess Medical Center and Harvard Medical School
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Albert Einstein College of Medicine
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University of California San Francisco
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Albert Einstein College of Medicine
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Department of Pharmaceutical Chemistry, University of California San Francisco
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University of California san francisco
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University of Washington
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Albert Einstein College of Medicine
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Stanford University
Co-authored papers 1
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New York University Grossman School of Medicine
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Tianjin International Joint Academy of Biomedicine
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Albert Einstein College of Medicine
Co-authored papers 1
NYU Langone Hospital - Brooklyn Brooklyn
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Brookhaven National Laboratory
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Albert Einstein College of Medicine
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