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Author Details

Greg Donahue
Penn Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania
2010
44
29
PMIDPaper TitleJournal TitlePublished Year
36536103A pioneer factor locally opens compacted chromatin to enable targeted ATP-dependent nucleosome remodeling.Nat Struct Mol Biol2023
37117791Spurious intragenic transcription is a feature of mammalian cellular senescence and tissue aging.Nat Aging2023
37292952Dynamic enhancer interactome promotes senescence and aging.bioRxiv2023
35061542Enzymatic transfer of acetate on histones from lysine reservoir sites to lysine activating sites.Sci Adv2022
34354237Diverse heterochromatin-associated proteins repress distinct classes of genes and repetitive elements.Nat Cell Biol2021
33636105FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity.Dev Cell2021
34861191An NK-like CAR T cell transition in CAR T cell dysfunction.Cell2021
34485932EU-RNA-seq for in vivo labeling and high throughput sequencing of nascent transcripts.STAR Protoc2021
34330844Longitudinal Analysis of Human Pancreatic Adenocarcinoma Development Reveals Transient Gene Expression Signatures.Mol Cancer Res2021
32203463Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones.Nat Genet2020
33033384Author Correction: An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease.Nat Genet2020
33277249Growth of pancreatic cancers with hemizygous chromosomal 17p loss of <i>MYBBP1A</i> can be preferentially targeted by PARP inhibitors.Sci Adv2020
32989324An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer's disease.Nat Genet2020
30689973Polycomb Repressive Complex 2 Proteins EZH1 and EZH2 Regulate Timing of Postnatal Hepatocyte Maturation and Fibrosis by Repressing Genes With Euchromatic Promoters in Mice.Gastroenterology2019
31761669Gcn5-Mediated Histone Acetylation Governs Nucleosome Dynamics in Spermiogenesis.Dev Cell2019
31207603TOX transcriptionally and epigenetically programs CD8[+] T cell exhaustion.Nature2019
30606806H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification.Science2019
29507413Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.Nat Neurosci2018
29556027Publisher Correction: Dysregulation of the epigenetic landscape of normal aging in Alzheimer's disease.Nat Neurosci2018
29440247KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis.Genes Dev2018
28562591Acetyl-CoA synthetase regulates histone acetylation and hippocampal memory.Nature2017
28086087RNA Binding to CBP Stimulates Histone Acetylation and Transcription.Cell2017
29272703Genomic and Proteomic Resolution of Heterochromatin and Its Restriction of Alternate Fate Genes.Mol Cell2017
28701476Detection of early pancreatic ductal adenocarcinoma with thrombospondin-2 and CA19-9 blood markers.Sci Transl Med2017
28912132Mitotic transcription and waves of gene reactivation during mitotic exit.Science2017
27058788The Pioneer Transcription Factor FoxA Maintains an Accessible Nucleosome Configuration at Enhancers for Tissue-Specific Gene Activation.Mol Cell2016
27630559Changes in the Transcriptome of Human Astrocytes Accompanying Oxidative Stress-Induced Senescence.Front Aging Neurosci2016
26833731MLL1 is essential for the senescence-associated secretory phenotype.Genes Dev2016
25691659Characterization of BRD4 during mammalian postmeiotic sperm development.Mol Cell Biol2015
26331536Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.Nature2015
26628362H4K44 Acetylation Facilitates Chromatin Accessibility during Meiosis.Cell Rep2015
26524528Autophagy mediates degradation of nuclear lamina.Nature2015
26159996H3K36 methylation promotes longevity by enhancing transcriptional fidelity.Genes Dev2015
25107471Dynamics of genomic H3K27me3 domains and role of EZH2 during pancreatic endocrine specification.EMBO J2014
25154414Histone methylation has dynamics distinct from those of histone acetylation in cell cycle reentry from quiescence.Mol Cell Biol2014
23355396Bookmarking by specific and nonspecific binding of FoxA1 pioneer factor to mitotic chromosomes.Genes Dev2013
24270890Senescent cells harbour features of the cancer epigenome.Nat Cell Biol2013
23934658Lamin B1 depletion in senescent cells triggers large-scale changes in gene expression and the chromatin landscape.Genes Dev2013
23636946Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality.Genome Res2013
23756653Rap1 relocalization contributes to the chromatin-mediated gene expression profile and pace of cell senescence.Genes Dev2013
22586276The linker histone plays a dual role during gametogenesis in Saccharomyces cerevisiae.Mol Cell Biol2012
23159369Facilitators and impediments of the pluripotency reprogramming factors' initial engagement with the genome.Cell2012
22964682Beyond fat grafting: what adipose tissue can teach us about the molecular mechanisms of human aging.Ann Plast Surg2012
20798317Genomic comparison of the ants Camponotus floridanus and Harpegnathos saltator.Science2010
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Collaborators

Shelley L Berger
Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 26
Benjamin A Garcia
University of Pennsylvania
Co-authored papers 10
Peter D Adams
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 6
Li-San Wang
Co-authored papers 6
Simone Sidoli
Co-authored papers 5
John Q Trojanowski
University of Pennsylvania
Co-authored papers 4
Danny Reinberg
HHMI/NYU Langone School of Medicine
Co-authored papers 3
Sager J Gosai
Co-authored papers 3
Tony McBryan
The Beatson Institute
Co-authored papers 2
Xiaolong Cui
First Hospital of ShanXi Medical University
Co-authored papers 2
Klaus H Kaestner
Department of Genetics and Institute for Diabetes, University of Pennsylvania
Co-authored papers 2
J??rgen Liebig
Arizona State University
Co-authored papers 2
Karl M Glastad
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Kajia Cao
Co-authored papers 2
Chuan He
Institute of Hematology, West China Hospital of Sichuan University
Co-authored papers 2
Daniel F Simola
1250 S. Collegeville Rd., Collegeville
Co-authored papers 2
Monica C Munoz-Torres
University of Colorado Anschutz Medical Campus
Co-authored papers 1
Rima Al-Awar
Ontario Institute for Cancer Research, University Avenue
Co-authored papers 1
Chris Tyler-Smith
Wellcome Sanger Institute
Co-authored papers 1
Darren E Hagen
Oklahoma State University
Co-authored papers 1
Justin T Reese
Lawrence Berkeley National Laboratory
Co-authored papers 1
Carl H June
University of Pennsylvania Department of Pathology & Laboratory Medicine
Co-authored papers 1
Evgeny M Zdobnov
University of Geneva Medical School
Co-authored papers 1
Jun Wang
Zhongnan Hospital of Wuhan University
Co-authored papers 1
Sanne Nygaard
Copenhagen University Hospital-Herlev and Gentofte
Co-authored papers 1
Alan Rawls
Arizona State University
Co-authored papers 1
Lumi Viljakainen
Ecology and Genetics Research Unit, University of Oulu
Co-authored papers 1
Eyal Privman
University of Haifa, Institute of Evolution
Co-authored papers 1
Richard R Meehan
Institute of Genetics and Molecular Medicine, University of Edinburgh
Co-authored papers 1
Jacobus J Boomsma
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Release 1.2