Author details

Full Name

Nikhil S Joshi

Affiliation

ORCID

Career Start Year

2004

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37459511	IL-7R licenses a population of epigenetically poised memory CD8<sup>+</sup> T cells with superior antitumor efficacy that are critical for melanoma memory.	Proc Natl Acad Sci U S A	2023
36315049	Clonal lineage tracing reveals mechanisms skewing CD8+ T cell fate decisions in chronic infection.	Journal of Experimental Medicine	2023
36423815	MR Imaging-Based InÂ Vivo Macrophage Imaging to Monitor Immune Response after Radiofrequency Ablation of the Liver.	Journal of Vascular and Interventional Radiology	2023
37586769	ScRNA-seq defines dynamic T-cell subsets in longitudinal colon and peripheral blood samples in immune checkpoint inhibitor-induced colitis.	J Immunother Cancer	2023
37344588	PD-1 maintains CD8 T cell tolerance towards cutaneous neoantigens.		2023
37343412	T follicular helper cells in cancer, tertiary lymphoid structures, and beyond.		2023
35216666	Tfh-cell-derived interleukin 21 sustains effector CD8 TÂ cell responses during chronic viral infection.	Immunity	2022
36875867	Novel Mouse Models for Cancer Immunology.		2022
35301723	Editorial: Perspectives on the landscape of immunology from Nikhil Joshi.	Immunology	2022
34597124	A reservoir of stem-like CD8<sup>+</sup> T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response.	Sci Immunol	2021
32719479	Inducible de novo expression of neoantigens in tumor cells and mice.	Nature Biotechnology	2021
34632444	A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma.	Cell Reports Methods	2021
34852236	Neoantigen-driven B cell and CD4Â T follicular helper cell collaboration promotes anti-tumor CD8 TÂ cell responses.	Cell	2021
31409707	Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation.	Proceedings of the National Academy of Sciences of the United States of America	2019
31076344	Incidence of pancreatitis with the use of immune checkpoint inhibitors (ICI) in advanced cancers: A systematic review and meta-analysis.	Pancreatology	2019
31011189	T cell IL-10 and IL-35 exhaust CD8 T cells in tumors.	Nature Immunology	2019
30332625	Lineage Specifiers in Lung Cancer Are Ahead of Their TIME.	Immunity	2018
30141018	Investigating Tumor-Associated Tertiary Lymphoid Structures in Murine Lung Adenocarcinoma.	Methods in Molecular Biology	2018
28069963	Pathogen boosted adoptive cell transfer immunotherapy to treat solid tumors.	Proceedings of the National Academy of Sciences of the United States of America	2017
28489818	A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma.	Nature	2017
27824591	NK Cell Responses Redefine Immunological Memory.	Journal of Immunology	2016
26887506	A Modular Assembly Platform for Rapid Generation of DNA Constructs.	Sci Rep	2016
26341400	Regulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses.	Immunity	2015
26018130	A versatile reporter system for CRISPR-mediated chromosomal rearrangements.	Genome Biol	2015
26503446	The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection.	Journal of Experimental Medicine	2015
25119044	CRISPR-mediated direct mutation of cancer genes in the mouse liver.	Nature	2014
25337879	Rapid modelling of cooperating genetic events in cancer through somatic genome editing.	Nature	2014
24659688	TLR4 ligands lipopolysaccharide and monophosphoryl lipid a differentially regulate effector and memory CD8+ T Cell differentiation.	Journal of Immunology	2014
23471395	Immunology. Guilty by association.	Science	2013
24466562	Koch Institute Symposium on Cancer Immunology and Immunotherapy.	Cancer Immunol Res	2013
21930973	Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells.	Journal of Immunology	2011
20410488	Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection.	Journal of Immunology	2010
20823247	Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival.	Proceedings of the National Academy of Sciences of the United States of America	2010
20921525	Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection.	Journal of Immunology	2010
19201385	Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation.	Vaccine	2009
18209024	Effector CD8 T cell development: a balancing act between memory cell potential and terminal differentiation.	Journal of Immunology	2008
18390712	Formation of IL-7Ralphahigh and IL-7Ralphalow CD8 T cells during infection is regulated by the opposing functions of GABPalpha and Gfi-1.	Journal of Immunology	2008
17723218	Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor.	Immunity	2007
17129212	Murine [corrected] myeloid dendritic cell-dependent toll-like receptor immunity is preserved with aging.	Aging Cell	2006
15944282	Deoxyuridine is generated preferentially in the nontranscribed strand of DNA from cells expressing activation-induced cytidine deaminase.	Journal of Immunology	2005
14718518	The uniformity of phagosome maturation in macrophages.	Journal of Cell Biology	2004