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Author Details

Joseph D Mancias
Dana-Farber Cancer Institute
1999
59
34
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37733830PD-1 Blockade Induces Reactivation of Nonproductive T-Cell Responses Characterized by NF-κB Signaling in Patients with Pancreatic Cancer.Clin Cancer Res2024
36459568Spatially Resolved Single-Cell Assessment of Pancreatic Cancer Expression Subtypes Reveals Co-expressor Phenotypes and Extensive Intratumoral Heterogeneity.Cancer Res2023
37210048A Multi-Institutional Phase 2 Trial of Ablative 5-Fraction Stereotactic Magnetic Resonance-Guided On-Table Adaptive Radiation Therapy for Borderline Resectable and Locally Advanced Pancreatic Cancer.Int J Radiat Oncol Biol Phys2023
37075122Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer.Sci Adv2023
37037306PTEN-induced kinase PINK1 supports colorectal cancer growth by regulating the labile iron pool.J Biol Chem2023
37230432Gender-Affirming Surgery and Cancer: Considerations for Radiation Oncologists for Pelvic Radiation in Transfeminine Patients.Int J Radiat Oncol Biol Phys2023
36924220Comparison of MR-soft tissue based versus biliary stent based alignment for image guidance in pancreatic SBRT.J Appl Clin Med Phys2023
34531254An <i>In Vivo</i> CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML.Cancer Discov2022
35771494Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS-MAPK Pathway Inhibition in Pancreatic Cancer.Cancer Discov2022
36553637Proteomic and Transcriptomic Landscapes of Alström and Bardet-Biedl Syndromes.Genes (Basel)2022
36129461Neoadjuvant Chemotherapy Is Associated with Altered Immune Cell Infiltration and an Anti-Tumorigenic Microenvironment in Resected Pancreatic Cancer.Clin Cancer Res2022
36300789Covalent disruptor of YAP-TEAD association suppresses defective Hippo signaling.Elife2022
35320352Multicancer Early Detection Technologies: A Review Informed by Past Cancer Screening Studies.Cancer Epidemiol Biomarkers Prev2022
34951957Reuterin in the healthy gut microbiome suppresses colorectal cancer growth through altering redox balance.Cancer Cell2022
34990508Modulation of the HIF2α-NCOA4 axis in enterocytes attenuates iron loading in a mouse model of hemochromatosis.Blood2022
33398154Reimagining high-throughput profiling of reactive cysteines for cell-based screening of large electrophile libraries.Nat Biotechnol2021
33883167Selective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer.Cancer Discov2021
33531365Autophagy is required for proper cysteine homeostasis in pancreatic cancer through regulation of SLC7A11.Proc Natl Acad Sci U S A2021
34801048Multiomic analysis on human cell model of wolfram syndrome reveals changes in mitochondrial morphology and function.Cell Commun Signal2021
34011631cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes.Sci Transl Med2021
34233309Improvements in beam's eye view fiducial tracking using a novel multilayer imager.Phys Med Biol2021
34370287The Role of NCOA4-Mediated Ferritinophagy in Ferroptosis.Adv Exp Med Biol2021
32376951Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.Nature2020
31802297Neoadjuvant Therapy is Associated with Improved Survival in Borderline-Resectable Pancreatic Cancer.Ann Surg Oncol2020
31880208ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging.Autophagy2020
33142117Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer.Cell2020
33027658Respiratory Supercomplexes Promote Mitochondrial Efficiency and Growth in Severely Hypoxic Pancreatic Cancer.Cell Rep2020
32755567Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing.Cell Chem Biol2020
32948771Rapid and direct control of target protein levels with VHL-recruiting dTAG molecules.Nat Commun2020
32341021Selective Alanine Transporter Utilization Creates a Targetable Metabolic Niche in Pancreatic Cancer.Cancer Discov2020
32234489Defining and Targeting Adaptations to Oncogenic KRAS<sup>G12C</sup> Inhibition Using Quantitative Temporal Proteomics.Cell Rep2020
30630985NCOA4 maintains murine erythropoiesis via cell autonomous and non-autonomous mechanisms.Haematologica2019
31787617The role of nuclear receptor co-activator 4 in erythropoiesis (Reply to Nai <i>et al</i>.).Haematologica2019
30930742NCOA4-Mediated Ferritinophagy: A Potential Link to Neurodegeneration.Front Neurosci2019
30360520The Role of NCOA4-Mediated Ferritinophagy in Health and Disease.Pharmaceuticals (Basel)2018
29892083Plasticity in binding confers selectivity in ligand-induced protein degradation.Nat Chem Biol2018
29971463What Patients Look for When Browsing Online for Pancreatic Cancer: The Bait Behind the Byte.World J Surg2018
28029328When, What, and Why of Perioperative Treatment of Potentially Curable Pancreatic Adenocarcinoma.J Clin Oncol2017
31119201The Role of Autophagy in Cancer.Annu Rev Cancer Biol2017
28375945Proteome-Wide Protein Expression Profiling Across Five Pancreatic Cell Lines.Pancreas2017
28708929Stereotactic body radiotherapy for unresected pancreatic cancer: A nationwide review.Cancer2017
28671190Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism.Nat Commun2017
26918041Stereotactic Body Radiotherapy (SBRT) Reirradiation for Recurrent Pancreas Cancer.J Cancer2016
27974163Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate.Neuron2016
27144966Assessing the Accuracy and Readability of Online Health Information for Patients With Pancreatic Cancer.JAMA Surg2016
26799652Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Autophagy2016
26953261Mechanisms of Selective Autophagy in Normal Physiology and Cancer.J Mol Biol2016
26436293Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis.Elife2015
26516357Stereotactic Body Radiotherapy (SBRT) for Intrahepatic and Hilar Cholangiocarcinoma.J Cancer2015
24388967KRAS: feeding pancreatic cancer proliferation.Trends Biochem Sci2014
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Harvard Medical School
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Harvard Medical School
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Lahey Hospital and Medical Center
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Keck School of Medicine of the University of California los angeles
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University of California San Francisco
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Queen's University Belfast
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and Barnett Institute, Northeastern University
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The Microsoft Research University of Trento
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Nikolai V Gorbunov
Armed Forces Radiobiology Research Institute
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Oncode Institute
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Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
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Arianna L Kim
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Carlos L??pez-Ot??n
Instituto Universitario de Oncologia, Universidad de Oviedo
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Boston Children's Hospital
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New York University Grossman School of Medicine
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David Sulzer
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
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Ernst J Wolvetang
Australian Institute for Bioengineering and Nanotechnology, University of Queensland
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Manish K Aghi
University of California san francisco
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Hirotaka Watada
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Sara Cherry
University of Pennsylvania
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Jeremy F Reiter
Cardiovascular Research Institute
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Release 1.2