Author details

Full Name

Joerg Heeren

Affiliation

ORCID

Career Start Year

1996

Papers

193

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37099421	Live-cell imaging identifies cAMP microdomains regulating Î²-adrenoceptor-subtype-specific lipolytic responses in human white adipocytes.		2023
36053190	Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.	Hepatology	2023
37580603	Short-term dietary changes can result in mucosal and systemic immune depression.	Nat Immunol	2023
37610219	Acute Deletion of the Glucocorticoid Receptor in Hepatocytes Disrupts Postprandial Lipid Metabolism in Male Mice.		2023
36907508	The lysosomal LAMTOR / Ragulator complex is essential for nutrient homeostasis in brown adipose tissue.		2023
36766683	TREM2 Regulates the Removal of Apoptotic Cells and Inflammatory Processes during the Progression of NAFLD.		2023
35167093	Metabolic Turnover Studies to Quantify Energy Uptake by Thermogenic Adipose Tissues of Mice.	Methods in Molecular Biology	2022
35739571	Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity.	Microbiome	2022
35422714	Role of Endothelial Cell Lipoprotein Lipase for Brown Adipose Tissue Lipid and Glucose Handling.	Frontiers in Physiology	2022
35931682	Pregnancy-induced maternal microchimerism shapes neurodevelopment and behavior in mice.	Nat Commun	2022
35478959	Cold-Induced Lipoprotein Clearance in -Deficient Mice.	Frontiers in Cell and Developmental Biology	2022
35790189	Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.	Nature	2022
36192408	Increased concentrations of conjugated bile acids are associated with osteoporosis in PSC patients.	Scientific Reports	2022
36497069	Role of Liver CD38 in the Regulation of Metabolic Pathways during Cold-Induced Thermogenesis in Mice.		2022
33373032	Novel Adipose Tissue Targets to Prevent and Treat Atherosclerosis.	Handbook of Experimental Pharmacology	2022
34927460	Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.	Am J Physiol Endocrinol Metab	2022
35208244	A Gas Chromatography Mass Spectrometry-Based Method for the Quantification of Short Chain Fatty Acids.	Metabolites	2022
34957913	Lysosomal acid lipase promotes endothelial proliferation in cold-activated adipose tissue.	Adipocyte	2022
34895500	Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans.	Cell Metab	2022
34835990	Role of CD38 in Adipose Tissue: Tuning Coenzyme Availability?	Nutrients	2021
34236487	Role of bile acids in inflammatory liver diseases.	Seminars in Immunopathology	2021
33748195	Endothelial Lipase Is Involved in Cold-Induced High-Density Lipoprotein Turnover and Reverse Cholesterol Transport in Mice.	Frontiers in Cardiovascular Medicine	2021
33526599	Comment on "Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to ".	Journal of Immunology	2021
33892169	Metabolic-associated fatty liver disease and lipoprotein metabolism.	Molecular Metabolism	2021
33516944	TFEB deficiency attenuates mitochondrial degradation upon brown adipose tissue whitening at thermoneutrality.	Molecular Metabolism	2021
33440156	Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.	Cell Reports	2021
32932016	Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice.	Cellular and Molecular Gastroenterology and Hepatology	2021
33357458	Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation.		2021
33346377	Nanoparticle-mediated targeting of autoantigen peptide to cross-presenting liver sinusoidal endothelial cells protects from CD8 T-cell-driven autoimmune cholangitis.	Immunology	2021
33010451	CD38 downregulation modulates NAD and NADP(H) levels in thermogenic adipose tissues.	Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids	2021
34580477	Isthmin 1 - a novel insulin-like adipokine.	Nature Reviews Endocrinology	2021
34685636	Oxysterol 7-Î± Hydroxylase (CYP7B1) Attenuates Metabolic-Associated Fatty Liver Disease in Mice at Thermoneutrality.	Cells	2021
34784249	Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca signaling during T cell activation.	Science Signaling	2021
31243055	Alterations of the bile microbiome in primary sclerosing cholangitis.	Gut	2020
32005828	A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism.	Nat Commun	2020
31664461	Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells.	Cellular and Molecular Life Sciences	2020
32769145	Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice.	Journal of Lipid Research	2020
33092056	Inulin Supplementation Disturbs Hepatic Cholesterol and Bile Acid Metabolism Independent from Housing Temperature.	Nutrients	2020
32588544	Apolipoprotein E4 disrupts the neuroprotective action of sortilin in neuronal lipid metabolism and endocannabinoid signaling.	Alzheimer's and Dementia	2020
33193086	Thermoneutrality-Induced Macrophage Accumulation in Brown Adipose Tissue Does Not Impair the Tissue's Competence for Cold-Induced Thermogenic Recruitment.	Frontiers in Endocrinology	2020
33025427	The P2X7 ion channel is dispensable for energy and metabolic homeostasis of white and brown adipose tissues.	Purinergic Signalling	2020
33024915	Therapeutic Targeting of Myeloperoxidase Attenuates NASH in Mice.	Hepatology Communications	2020
30477037	Development of the Metabolic Syndrome: Study Design and Baseline Data of the Lufthansa Prevention Study (LUPS), A Prospective Observational Cohort Survey.		2020
31296970	The endocrine function of adipose tissues in health and cardiometabolic disease.	Nature Reviews Endocrinology	2019
30576247	Intact innervation is essential for diet-induced recruitment of brown adipose tissue.	American Journal of Physiology - Endocrinology and Metabolism	2019
30468287	Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine.	Diabetes/Metabolism Research and Reviews	2019
31189119	Thyroid-Hormone-Induced Browning of White Adipose Tissue Does Not Contribute to Thermogenesis and Glucose Consumption.	Cell Reports	2019
30813320	Effects of Pharmacological Thermogenic Adipocyte Activation on Metabolism and Atherosclerotic Plaque Regression.	Nutrients	2019
30904610	PID1 regulates insulin-dependent glucose uptake by controlling intracellular sorting of GLUT4-storage vesicles.		2019
30855252	Scanning transmission X-ray microscopy with efficient X-ray fluorescence detection (STXM-XRF) for biomedical applications in the soft and tender energy range.	Journal of Synchrotron Radiation	2019