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Author Details

Bernard Khor
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
1998
38
23
PMIDPaper TitleJournal TitlePublished Year
37147460Down syndrome: insights into autoimmune mechanisms.Nat Rev Rheumatol2023
35020411Deep immune phenotyping reveals similarities between aging, Down syndrome, and autoimmunity.Sci Transl Med2022
36654851FRTX-02, a selective and potent inhibitor of DYRK1A, modulates inflammatory pathways in mouse models of psoriasis and atopic dermatitis.J Transl Autoimmun2022
34268067Opportunities, barriers, and recommendations in down syndrome research.Transl Sci Rare Dis2021
33831225Two roads diverged: Emerging lessons from IVIG about hemolysis.Transfusion2021
34378531Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome.Elife2021
34124936The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4<sup>+</sup> T Cells via a Novel CDK8-GATA3-FOXP3 Pathway.Mol Cell Biol2021
32522834Cell Type- and Stimulation-Dependent Transcriptional Programs Regulated by Atg16L1 and Its Crohn's Disease Risk Variant T300A.J Immunol2020
31451676Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1.J Immunol2019
27523957Regulatory T Cells: Central Concepts from Ontogeny to Therapy.Transfus Med Rev2017
28805801Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells.Nat Chem Biol2017
27224444Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function in Vivo.ACS Chem Biol2016
26492443Factor V Leiden.Am J Hematol2016
25998054The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.Elife2015
25114223Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells.Proc Natl Acad Sci U S A2014
25293789Activated protein C resistance testing for factor V Leiden.Am J Hematol2014
23327930ATG5 regulates plasma cell differentiation.Autophagy2013
24168452Selective modulation of autophagy, innate immunity, and adaptive immunity by small molecules.ACS Chem Biol2013
22473489Advances in laboratory testing for thrombophilia.Am J Hematol2012
21677747Genetics and pathogenesis of inflammatory bowel disease.Nature2011
21765899Out-of-frame T cell receptor beta transcripts are eliminated by multiple pathways in vivo.PLoS One2011
20309856Laboratory tests for protein C deficiency.Am J Hematol2010
21108326Laboratory tests for antithrombin deficiency.Am J Hematol2010
19070901Functional overlap in the cis-acting regulation of the V(D)J recombination at the TCRbeta locus.Mol Immunol2009
19665682Laboratory evaluation of hypercoagulability.Clin Lab Med2009
19556863Chimeric IgH-TCRalpha/delta translocations in T lymphocytes mediated by RAG.Cell Cycle2009
18572095Toward a molecular explanation for cross-presentation of antigens to the immune system.Transfus Med Rev2008
16581775Proteasome activator PA200 is required for normal spermatogenesis.Mol Cell Biol2006
15719363Intra- and inter-allelic ordering of T cell receptor beta chain gene assembly.Eur J Immunol2005
15642954Chromosomal excision of TCRdelta chain genes is dispensable for alphabeta T cell lineage commitment.Int Immunol2005
15640803Regulation of T cell receptor beta allelic exclusion at a level beyond accessibility.Nat Immunol2005
15242394Regulation of T-cell receptor beta-chain gene assembly by recombination signals: the beyond 12/23 restriction.Immunol Rev2004
12496374Cutting edge: targeting of V beta to D beta rearrangement by RSSs can be mediated by the V(D)J recombinase in the absence of additional lymphoid-specific factors.J Immunol2003
12949501T-cell glucocorticoid receptor is required to suppress COX-2-mediated lethal immune activation.Nat Med2003
11869897Allelic exclusion at the TCRbeta locus.Curr Opin Immunol2002
10367896Developmental regulation of TCR delta locus accessibility and expression by the TCR delta enhancer.Immunity1999
9782123Assembly of productive T cell receptor delta variable region genes exhibits allelic inclusion.J Exp Med1998
9850857Accessibility control of variable region gene assembly during T-cell development.Immunol Rev1998
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Collaborators

Ramnik J Xavier
Broad Institute of MIT and Harvard
Co-authored papers 10
Alykhan F Shamji
Center for the Science of Therapeutics, Broad Institute
Co-authored papers 6
Stuart L Schreiber
Broad Institute
Co-authored papers 5
Thomas B Sundberg
Cutaneous Biology Research Center
Co-authored papers 5
Nathanael S Gray
Harvard Medical School
Co-authored papers 4
Isabel Latorre
Co-authored papers 3
Liv Johannessen
Harvard Medical Schoolgrid.471403.5
Co-authored papers 3
Isabelle Marie
Centre Hospitalo-Universitaire de Rouen
Co-authored papers 2
Peter S Linsley
8Benaroya Research Institute
Co-authored papers 2
Vivian H Gersuk
Center for Systems Immunology, Benaroya Research Institute
Co-authored papers 2
David E Levy
NYU Grossman School of Medicine
Co-authored papers 2
Kaitlin J Flynn
Center for Systems Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 2
Jane H Buckner
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 2
Alex Hu
Center for Systems Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Ziaur S M Rahman
Pennsylvania State University College of Medicine
Co-authored papers 1
Keagan G Moo
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Agnès Gardet
Co-authored papers 1
Thomas Ried
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Carla J Greenbaum
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 1
John J O'Shea
National Institute of Arthritis, National Institutes of Health
Co-authored papers 1
Lisa M Jacola
St. Jude Children's Research Hospital
Co-authored papers 1
Cate Speake
Center for Interventional Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Keagan G Moo
Benaroya Research Institute
Co-authored papers 1
Mark J Daly
Massachusetts General Hospital
Co-authored papers 1
Leonard B Maggi
Washington University School of Medicine
Co-authored papers 1
Elizabeth Head
University of California Irvine
Co-authored papers 1
Thomas Decker
University of Vienna
Co-authored papers 1
Sonja A Rasmussen
The Johns Hopkins University School of Medicine
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Release 1.2