Author details

Full Name

Alexandra C Walls

Affiliation

ORCID

Career Start Year

2016

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37300832	Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail.	Cell Rep	2023
35076256	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement.	Science	2022
35700730	Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein.	Cell	2022
36356052	SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines.	Sci Immunol	2022
35879941	Safety and immunogenicity of a SARS-CoV-2 recombinant protein nanoparticle vaccine (GBP510) adjuvanted with AS03: A randomised, placebo-controlled, observer-blinded phase 1/2 trial.	eClinicalMedicine	2022
36206752	Antigen- and scaffold-specific antibody responses to protein nanoparticle immunogens.	Cell Reports Medicine	2022
35484405	Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants.	Nat Biotechnol	2022
36203553	Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape.	bioRxiv	2022
35864232	Author Correction: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.	Nature	2022
35677069	Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.	bioRxiv	2022
35988541	Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice.	Cell Rep	2022
35412328	Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice.	Sci Transl Med	2022
36264829	Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.	Science	2022
35857703	ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies.	Science	2022
35857529	Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines.	Science	2022
35606518	Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice.	NPJ Vaccines	2022
36399443	Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains.	PLoS Pathogens	2022
35976993	Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.	Sci Transl Med	2022
34990214	Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry.	Science	2022
35313570	Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines.	bioRxiv	2022
35016195	Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift.	Nature	2022
35118471	Structural changes in the SARS-CoV-2 spike E406W mutant escaping a clinical monoclonal antibody cocktail.	bioRxiv	2022
35114688	ACE2 binding is an ancestral and evolvable trait of sarbecoviruses.	Nature	2022
35123650	SARS-CoV-2 breakthrough infections elicit potent, broad, and durable neutralizing antibody responses.	Cell	2022
34931194	Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift.	bioRxiv	2021
33706364	Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies.	Nature	2021
33851169	Structural basis for broad sarbecovirus neutralization by a human monoclonal antibody.	bioRxiv	2021
33795432	Designed proteins assemble antibodies into modular nanocages.	Science	2021
34280951	Broad sarbecovirus neutralization by a human monoclonal antibody.	Nature	2021
33469588	N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.	bioRxiv	2021
34268509	Multivalent designed proteins protect against SARS-CoV-2 variants of concern.	bioRxiv	2021
33619509	SARS-CoV-2 B.1.1.7 sensitivity to mRNA vaccine-elicited, convalescent and monoclonal antibodies.	medRxiv	2021
34267764	Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design.	Front Immunol	2021
34210893	SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern.	Science	2021
34261126	SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.	Nature	2021
33873199	Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.	Nature	2021
33981021	Structural basis for broad coronavirus neutralization.	Nature Structural and Molecular Biology	2021
34189528	Detection of antibodies neutralizing historical and emerging SARS-CoV-2 strains using a thermodynamically coupled de novo biosensor system.	bioRxiv	2021
33821281	SARS-CoV-2 immune evasion by variant B.1.427/B.1.429.	bioRxiv	2021
33761326	N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.	Cell	2021
34344823	Broad betacoronavirus neutralization by a stem helix-specific human antibody.	Science	2021
34328683	Discovery and Characterization of Spike N-Terminal Domain-Binding Aptamers for Rapid SARS-CoV-2 Detection.	Angew Chem Int Ed Engl	2021
33758839	Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.	bioRxiv	2021
33594366	Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates.	bioRxiv	2021
33398277	Structural basis for broad coronavirus neutralization.		2021
34464958	Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies.	Nature	2021
34401880	Molecular basis of immune evasion by the delta and kappa SARS-CoV-2 variants.	bioRxiv	2021
34981060	SARS-CoV-2 spike conformation determines plasma neutralizing activity.	bioRxiv	2021
34671770	Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry.	bioRxiv	2021
34619077	Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.	Cell	2021