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Author Details

René E M Toes
1992
467
93
PMIDPaper TitleJournal TitlePublished Year
37480150Anti-carbamylated protein antibodies in systemic sclerosis.2023
36418483Glycobiology of rheumatic diseases.Nature reviews. Rheumatology2023
36403538Autoreactive B cell responses targeting nuclear antigens in systemic sclerosis: Implications for disease pathogenesis.Seminars in Arthritis and Rheumatism2023
37725442Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3+ memory B cells and plasmablasts.2023
37788903IgM antibodies against acetylated proteins as a possible starting point of the anti-modified protein antibody response in rheumatoid arthritis.2023
38053459Antibodies against advanced glycation end-products and malondialdehyde-acetaldehyde adducts identify a new specific subgroup of hitherto patients with seronegative arthritis with a distinct clinical phenotype and an HLA class II association.2023
37862070Effect of Antigen Valency on Autoreactive B-Cell Targeting.2023
36716825Differences in IgG autoantibody Fab glycosylation across autoimmune diseases.2023
37209914Addressing the key issue: Antigen-specific targeting of B cells in autoimmune diseases.2023
36890568Geo-epidemiology of autoantibodies in rheumatoid arthritis: comparison between four ethnically diverse populations.2023
36823186Author Correction: Glycobiology of rheumatic diseases.2023
36754962A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis.2023
37066741Tramadol/paracetamol treatment attenuates the development of collagen antibody-induced arthritis and interferes with prednisolone treatment in mice.2023
36480251IgG Fab Glycans Hinder FcRn-Mediated Placental Transport.2023
36746531Progression from suspected to definite systemic sclerosis and the role of anti-topoisomerase I antibodies.2023
37306812Spondyloarthritis mass cytometry immuno-monitoring: a proof of concept study in the tight-control and treat-to target TiCoSpA trial.2023
37507206Anti-topoisomerase, but not anti-centromere B cell responses in systemic sclerosis display active, Ig-secreting cells associated with lung fibrosis.2023
37498177A photoaffinity glycan-labeling approach to investigate immunoglobulin glycan-binding partners.2023
35138894Surface Ig variable domain glycosylation affects autoantigen binding and acts as threshold for human autoreactive B cell activation.Science advances2022
36371234Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial.Trials2022
35459696Cross-reactivity of anti-modified protein antibodies is also present in predisease and individuals without rheumatoid arthritis.Annals of the Rheumatic Diseases2022
35705253At Critically Low Antigen Densities, IgM Hexamers Outcompete Both IgM Pentamers and IgG1 for Human Complement Deposition and Complement-Dependent Cytotoxicity.Journal of Immunology2022
36229887Absence of Epstein-Barr virus DNA in anti-citrullinated protein antibody-expressing B cells of patients with rheumatoid arthritis.2022
36336400Comprehensive overview of autoantibody isotype and subclass distribution.Journal of Allergy and Clinical Immunology2022
36278483Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis.JCI Insight2022
35416963In rheumatoid arthritis patients, total IgA1 and IgA2 levels are elevated: implications for the mucosal origin hypothesis.Rheumatology2022
36197299Comparative Photoaffinity Profiling of Omega-3 Signaling Lipid Probes Reveals Prostaglandin Reductase 1 as a Metabolic Hub in Human Macrophages.Journal of the American Chemical Society2022
35606567From risk to chronicity: evolution of autoreactive B cell and antibody responses in rheumatoid arthritis.Nature reviews. Rheumatology2022
35855325Benchmarking computational methods for B-cell receptor reconstruction from single-cell RNA-seq data.NAR Genomics and Bioinformatics2022
34285049Determining in which pre-arthritis stage HLA-shared epitope alleles and smoking exert their effect on the development of rheumatoid arthritis.Ann Rheum Dis2022
35259296Multifunctional, Multivalent PIC Polymer Scaffolds for Targeting Antigen-Specific, Autoreactive B Cells.ACS Biomaterials Science and Engineering2022
35188715IgG Anti-Citrullinated Protein Antibody Variable Domain Glycosylation Increases Before the Onset of Rheumatoid Arthritis and Stabilizes Thereafter: A Cross-Sectional Study Encompassing ~1,500 Samples.Arthritis and Rheumatology2022
34385139Genetic predisposition (HLA-SE) is associated with ACPA-IgG variable domain glycosylation in the predisease phase of RA.Annals of the Rheumatic Diseases2022
34998422Hyaluronidase treatment of synovial fluid is required for accurate detection of inflammatory cells and soluble mediators.2022
34876234Evolution of anti-modified protein antibody responses can be driven by consecutive exposure to different post-translational modifications.2021
32482649Association Between Centromere- and Topoisomerase-specific Immune Responses and the Degree of Microangiopathy in Systemic Sclerosis.Journal of Rheumatology2021
33784344Light chain skewing in autoantibodies and B-cell receptors of the citrullinated antigen-binding B-cell response in rheumatoid arthritis.PLoS ONE2021
34212151Bioorthogonal protein labelling enables the study of antigen processing of citrullinated and carbamylated auto-antigens.RSC Chemical Biology2021
34042326Anticentromere Antibody Levels and Isotypes and the Development of Systemic Sclerosis.Arthritis and Rheumatology2021
33648960Onset of rheumatoid arthritis after COVID-19: coincidence or connected?Annals of the Rheumatic Diseases2021
32594174Arthritis autoantibodies in individuals without rheumatoid arthritis: follow-up data from a Dutch population-based cohort (Lifelines).Rheumatology2021
33144303Do autoantibody-responses mature between presentation with arthralgia suspicious for progression to rheumatoid arthritis and development of clinically apparent inflammatory arthritis? A longitudinal serological study.Annals of the Rheumatic Diseases2021
32896247Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls.Clinical and Experimental Rheumatology2021
34715910Immunoprofiling of early, untreated rheumatoid arthritis using mass cytometry reveals an activated basophil subset inversely linked to ACPA status.2021
34479638Cross-reactivity of IgM anti-modified protein antibodies in rheumatoid arthritis despite limited mutational load.2021
31409590Response to: "How to communicate in science" by Klareskog .Annals of the Rheumatic Diseases2020
32133009A Comparison of Immunoglobulin Variable Region N-Linked Glycosylation in Healthy Donors, Autoimmune Disease and Lymphoma.Frontiers in Immunology2020
31634584Complement component C1q is produced by isolated articular chondrocytes.Osteoarthritis and Cartilage2020
32041746Antibodies and B cells recognising citrullinated proteins display a broad cross-reactivity towards other post-translational modifications.Annals of the Rheumatic Diseases2020
32276504Neutrophil Extracellular Traps (NETs) Take the Central Stage in Driving Autoimmune Responses.Cells2020
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