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Author Details

Paola Cappello
University of Turin
1998
88
37
PMIDPaper TitleJournal TitlePublished Year
35623884Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer.Gut2023
37914939IL-1β<sup>+</sup> macrophages fuel pathogenic inflammation in pancreatic cancer.Nature2023
34922945Docking Protein p130Cas Regulates Acinar to Ductal Metaplasia During Pancreatic Adenocarcinoma Development and Pancreatitis.Gastroenterology2022
36612133Post-Translational Modifications in Tumor-Associated Antigens as a Platform for Novel Immuno-Oncology Therapies.Cancers (Basel)2022
35271535Modulation of LTCC Pathways by a Melusin Mimetic Increases Ventricular Contractility During LPS-Induced Cardiomyopathy.Shock2022
34993937Discovery of Targets for Cancer Immunoprevention.Methods Mol Biol2022
34479922Intratumoral injection of TLR9 agonist promotes an immunopermissive microenvironment transition and causes cooperative antitumor activity in combination with anti-PD1 in pancreatic cancer.J Immunother Cancer2021
33917869SIO: A Spatioimageomics Pipeline to Identify Prognostic Biomarkers Associated with the Ovarian Tumor Microenvironment.Cancers (Basel)2021
33804240The Glycolytic Pathway as a Target for Novel Onco-Immunology Therapies in Pancreatic Cancer.Molecules2021
33802061IL17A Depletion Affects the Metabolism of Macrophages Treated with Gemcitabine.Antioxidants (Basel)2021
33526692IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions.Proc Natl Acad Sci U S A2021
34436366Effects of Steroids and Tocilizumab on the Immune Response Profile of Patients with COVID-19-Associated ARDS Requiring or Not Veno-Venous Extracorporeal Membrane Oxygenation.Membranes (Basel)2021
34552006Phosphoproteomics Identifies PI3K Inhibitor-selective Adaptive Responses in Pancreatic Cancer Cell Therapy and Resistance.Mol Cancer Ther2021
32397638Strigolactone Analogs Are Promising Antiviral Agents for the Treatment of Human Cytomegalovirus Infection.Microorganisms2020
35582441The dark side of immunotherapy: pancreatic cancer.Cancer Drug Resist2020
31994367Impact of imipenem concentration in lung perfusate and tissue biopsy during clinical ex-vivo lung perfusion of high-risk lung donors.Minerva Anestesiol2020
32019781Metabolome of Pancreatic Juice Delineates Distinct Clinical Profiles of Pancreatic Cancer and Reveals a Link between Glucose Metabolism and PD-1<sup>+</sup> Cells.Cancer Immunol Res2020
33115943In pancreatic cancer, chemotherapy increases antitumor responses to tumor-associated antigens and potentiates DNA vaccination.J Immunother Cancer2020
32778157Diabetes promotes invasive pancreatic cancer by increasing systemic and tumour carbonyl stress in Kras<sup>G12D/+</sup> mice.J Exp Clin Cancer Res2020
32234652Gut microbiota composition after diet and probiotics in overweight breast cancer survivors: a randomized open-label pilot intervention trial.Nutrition2020
30415234Stromal protein βig-h3 reprogrammes tumour microenvironment in pancreatic cancer.Gut2019
30770442Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1.Proc Natl Acad Sci U S A2019
30733286AhR controls redox homeostasis and shapes the tumor microenvironment in BRCA1-associated breast cancer.Proc Natl Acad Sci U S A2019
30394062Effects of liver ischemia-reperfusion injury on respiratory mechanics and driving pressure during orthotopic liver transplantation.Minerva Anestesiol2019
29348263Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth.Circulation2018
29941541Soluble stroma-related biomarkers of pancreatic cancer.EMBO Mol Med2018
29462900Next Generation Immunotherapy for Pancreatic Cancer: DNA Vaccination is Seeking New Combo Partners.Cancers (Basel)2018
29708394Extracorporeal CO<sub>2</sub> Removal May Improve Renal Function of Patients with Acute Respiratory Distress Syndrome and Acute Kidney Injury: An Open-Label, Interventional Clinical Trial.Am J Respir Crit Care Med2018
29533466The advanced glycation end-product N<sup>ϵ</sup> -carboxymethyllysine promotes progression of pancreatic cancer: implications for diabetes-associated risk and its prevention.J Pathol2018
29059164FAM49B, a novel regulator of mitochondrial function and integrity that suppresses tumor metastasis.Oncogene2018
27814656Alpha-Enolase (<i>ENO1</i>), a potential target in novel immunotherapies.Front Biosci (Landmark Ed)2017
28086938Alpha-enolase (ENO1) controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis.J Hematol Oncol2017
29308326Depletion of tumor-associated macrophages switches the epigenetic profile of pancreatic cancer infiltrating T cells and restores their anti-tumor phenotype.Oncoimmunology2017
29221133Endogenous glutamine decrease is associated with pancreatic cancer progression.Oncotarget2017
28540328Next generation of cancer immunotherapy calls for combination.Oncoscience2017
27906678Humoral immune responses toward tumor-derived antigens in previously untreated patients with chronic lymphocytic leukemia.Oncotarget2017
26704357A bioluminescent mouse model of proliferation to highlight early stages of pancreatic cancer: A suitable tool for preclinical studies.Ann Anat2016
26540149Neuromuscular Blocking Agent Cisatracurium Attenuates Lung Injury by Inhibition of Nicotinic Acetylcholine Receptor-α1.Anesthesiology2016
26558403The balance between IL-17 and IL-22 produced by liver-infiltrating T-helper cells critically controls NASH development in mice.Clin Sci (Lond)2016
26425874Ventilatory Management During Normothermic Ex Vivo Lung Perfusion: Effects on Clinical Outcomes.Transplantation2016
27210467Peripheral ENO1-specific T cells mirror the intratumoral immune response and their presence is a potential prognostic factor for pancreatic adenocarcinoma.Int J Oncol2016
27179037Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression.Cancer Discov2016
26960761Regulation of Langerhans cell functions in a hypoxic environment.J Mol Med (Berl)2016
26734996Targeting the Warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest.Oncotarget2016
25860938Targeting of surface alpha-enolase inhibits the invasiveness of pancreatic cancer cells.Oncotarget2015
27141376Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma.Oncoimmunology2015
27467915Anti-α-enolase antibody limits the invasion of myeloid-derived suppressor cells and attenuates their restraining effector T cell response.Oncoimmunology2015
23708664Role of Nek2 on centrosome duplication and aneuploidy in breast cancer cells.Oncogene2014
24987872Class II transactivator-induced MHC class II expression in pancreatic cancer cells leads to tumor rejection and a specific antitumor memory response.Pancreas2014
24668647Chimeric rat/human HER2 efficiently circumvents HER2 tolerance in cancer patients.Clin Cancer Res2014
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Collaborators

Chiara Riganti
University of Turin
Co-authored papers 5
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Chiara Gorrini
Division of Clinical Studies, The Institute of Cancer Research
Co-authored papers 3
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Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network
Co-authored papers 3
Manuela Iezzi
Co-authored papers 2
Emanuel F Petricoin
Center for Applied Proteomics and Molecular Medicine, George Mason University
Co-authored papers 2
Thorsten Berger
Princess Margaret Cancer Centre, University Health Network
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David W Cescon
Princess Margaret Cancer Centre
Co-authored papers 2
Massimo Alessio
IRCCS - San Raffaele Scientific Institute
Co-authored papers 2
Patrizia Caposio
Vaccine and Gene Therapy Institute, Oregon Health & Science University
Co-authored papers 1
Andrew J Elia
University Health Network, Princess Margaret Cancer Centre
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Bruce Youngson
University Health Network
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Stephen T C Wong
Houston Methodist Research Institute
Co-authored papers 1
Mark A Valasek
Co-authored papers 1
Roman Sasik
Center for Computational Biology & Bioinformatics (CCBB), University of California
Co-authored papers 1
Syed Haider
Institute of Cancer Research
Co-authored papers 1
Luigi Naldini
Vita-Salute San Raffaele University
Co-authored papers 1
Michael Bouvet
Co-authored papers 1
Dan Chi-Chia Lin
College of Life Science, Fujian Normal University
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
Susan J Done
University Health Network
Co-authored papers 1
Lance A Liotta
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Jacqueline M Mason
Campbell Family Institute for Breast Cancer Research, University Health Network
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Vincenzo Cantaluppi
University of Eastern Piedmont.
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Florent Ginhoux
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Heiko Blaser
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Release 1.2