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Author Details

Clint L Miller
University of Virginia
2007
67
28
Gloria M Sheynkman (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36728943Cardiovascular utility of single cell RNA-Seq.Curr Opin Cardiol2023
37546840Leukocytes carrying <i>Clonal Hematopoiesis of Indeterminate Potential</i> (CHIP) Mutations invade Human Atherosclerotic Plaques.medRxiv2023
37770635Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.Nat Genet2023
37017084FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells.Circ Res2023
37199168<i>INKILN</i> is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10.Circulation2023
37461703Polygenic Risk Score Associates with Atherosclerotic Plaque Characteristics at Autopsy.bioRxiv2023
36923952Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation.Mol Ther Nucleic Acids2023
36922520An automatic entropy method to efficiently mask histology whole-slide images.Sci Rep2023
36719758CD163+ macrophages restrain vascular calcification, promoting the development of high-risk plaque.JCI Insight2023
36711681<i>INKILN</i> is a novel long noncoding RNA promoting vascular smooth muscle inflammation via scaffolding MKL1 and USP10.bioRxiv2023
36824883Integrative multi-ancestry genetic analysis of gene regulation in coronary arteries prioritizes disease risk loci.medRxiv2023
36597873Genetic Regulation of SMC Gene Expression and Splicing Predict Causal CAD Genes.Circ Res2023
34961328Integrative Prioritization of Causal Genes for Coronary Artery Disease.Circ Genom Precis Med2022
37920851Transcriptomic-based clustering of human atherosclerotic plaques identifies subgroups with different underlying biology and clinical presentation.Nat Cardiovasc Res2022
35768727Author Correction: Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk.Nat Genet2022
35714152The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1.PLoS Genet2022
35590109Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk.Nat Genet2022
36003902PlaqView 2.0: A comprehensive web portal for cardiovascular single-cell genomics.Front Cardiovasc Med2022
34849613Dynamic changes in chromatin accessibility are associated with the atherogenic transitioning of vascular smooth muscle cells.Cardiovasc Res2022
34871816Enhanced single-cell RNA-seq workflow reveals coronary artery disease cellular cross-talk and candidate drug targets.Atherosclerosis2022
34039022<i>APOL1</i> Genetic Variants Are Associated With Increased Risk of Coronary Atherosclerotic Plaque Rupture in the Black Population.Arterioscler Thromb Vasc Biol2021
33853350Clarifying the Distinct Roles of Smooth Muscle Cell-Derived Versus Macrophage Foam Cells and the Implications in Atherosclerosis.Arterioscler Thromb Vasc Biol2021
33532862Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.Eur Heart J2021
35174364Intersecting single-cell transcriptomics and genome-wide association studies identifies crucial cell populations and candidate genes for atherosclerosis.Eur Heart J Open2021
34493662Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy.Proc Natl Acad Sci U S A2021
34505007Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease.iScience2021
34016266Precision Medicine Approaches to Vascular Disease: JACC Focus Seminar 2/5.J Am Coll Cardiol2021
32541024Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade.Proc Natl Acad Sci U S A2020
31893970PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling.Circ Res2020
33040646Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells.Circ Res2020
31163979Inducible Pluripotent Stem Cell-Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome.Circulation2019
31539914The novel coronary artery disease risk gene JCAD/KIAA1462 promotes endothelial dysfunction and atherosclerosis.Eur Heart J2019
31014396TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression.Genome Med2019
30838214Multi-Omics Approaches to Study Long Non-coding RNA Function in Atherosclerosis.Front Cardiovasc Med2019
31043074Genetic Insights Into Smooth Muscle Cell Contributions to Coronary Artery Disease.Arterioscler Thromb Vasc Biol2019
31042164Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis.J Clin Invest2019
29440201Proefferocytic Therapy Promotes Transforming Growth Factor-β Signaling and Prevents Aneurysm Formation.Circulation2018
29988570GWAS Reveal Targets in Vessel Wall Pathways to Treat Coronary Artery Disease.Front Cardiovasc Med2018
30146127Genetic Regulatory Mechanisms of Smooth Muscle Cells Map to Coronary Artery Disease Risk Loci.Am J Hum Genet2018
30307970Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.PLoS Genet2018
30444878Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.PLoS Genet2018
29608647BART: a transcription factor prediction tool with query gene sets or epigenomic profiles.Bioinformatics2018
28481916TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells.PLoS Genet2017
27437576CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.Nature2016
28603781Genome-Wide Association Studies Candidate Gene to Dual Modifier of Nonalcoholic Steatohepatitis and Atherosclerosis.JACC Basic Transl Sci2016
27791092PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction.Proc Natl Acad Sci U S A2016
27586139Genetics and Genomics of Coronary Artery Disease.Curr Cardiol Rep2016
27386823Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci.Nat Commun2016
27470516Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.Arterioscler Thromb Vasc Biol2016
26020271Characterization of TCF21 Downstream Target Regions Identifies a Transcriptional Network Linking Multiple Independent Coronary Artery Disease Loci.PLoS Genet2015
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Collaborators

Thomas Quertermous
Co-authored papers 24
Jason C Kovacic
Co-authored papers 10
Mete Civelek
Center for Public Health Genomics, University of Virginia
Co-authored papers 8
Aloke V Finn
CVPath Institute
Co-authored papers 7
Eric E Schadt
Icahn School of Medicine at Mount Sinai
Co-authored papers 7
Themistocles L Assimes
Co-authored papers 6
Heribert Schunkert
Co-authored papers 5
Sylvia Nürnberg
Co-authored papers 5
Euan A Ashley
Stanford University
Co-authored papers 4
Stephen B Montgomery
Stanford University
Co-authored papers 4
Frederick E Dewey
Co-authored papers 4
Renu Virmani
CVPath Institute
Co-authored papers 4
Suna Onengut-Gumuscu
Co-authored papers 4
Simon Koplev
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 4
Ke Hao
Co-authored papers 4
Boxiang Liu
Co-authored papers 4
Liang Guo
CVPath Institute
Co-authored papers 4
Maryam Kavousi
University Medical Center Rotterdam
Co-authored papers 3
Rajeev Malhotra
Massachusetts General Hospital.
Co-authored papers 3
Chongzhi Zang
Center for Public Health Genomics, University of Virginia
Co-authored papers 3
Frank D Kolodgie
CVPath Institute
Co-authored papers 3
Patricia A Peyser
School of Public Health, University of Michigan ann arbor
Co-authored papers 3
Anshul Kundaje
Stanford University.
Co-authored papers 3
Neal L Weintraub
Medical College of Georgia, Augusta University
Co-authored papers 2
Abhiram S Rao
Co-authored papers 2
Ani Manichaikul
Co-authored papers 2
Anders Hamsten
Co-authored papers 2
Muredach P Reilly
Vagelos College of Physicians and Surgeons, Columbia University
Co-authored papers 2
Paul S de Vries
Co-authored papers 2
Steve E Humphries
Co-authored papers 2
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