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Author Details

Michael Y Tolstorukov
Dana-Farber Cancer Institute
2000
71
37
PMIDPaper TitleJournal TitlePublished Year
36780194ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma.Clin Cancer Res2023
37591951KDM6A epigenetically regulates subtype plasticity in small cell lung cancer.Nat Cell Biol2023
38076892Parsing digital or analogue TCR performance through piconewton forces.bioRxiv2023
36780194ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma.Clin Cancer Res2023
36810872Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment.Sci Rep2023
37126722PGE<sub>2</sub> alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate.Proc Natl Acad Sci U S A2023
37171617Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma.Cell Mol Life Sci2023
36849253Disruption of polyhomeotic polymerization decreases nucleosome occupancy and alters genome accessibility.Life Sci Alliance2023
38076892Parsing digital or analogue TCR performance through piconewton forces.bioRxiv2023
37591951KDM6A epigenetically regulates subtype plasticity in small cell lung cancer.Nat Cell Biol2023
37171617Single-cell molecular profiling using ex vivo functional readouts fuels precision oncology in glioblastoma.Cell Mol Life Sci2023
37126722PGE<sub>2</sub> alters chromatin through H2A.Z-variant enhancer nucleosome modification to promote hematopoietic stem cell fate.Proc Natl Acad Sci U S A2023
36849253Disruption of polyhomeotic polymerization decreases nucleosome occupancy and alters genome accessibility.Life Sci Alliance2023
36810872Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment.Sci Rep2023
34740862Diminished Efficacy of Programmed Death-(Ligand)1 Inhibition in STK11- and KEAP1-Mutant Lung Adenocarcinoma Is Affected by KRAS Mutation Status.J Thorac Oncol2022
35708671Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels.JAMA Oncol2022
36153311Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors.Nat Commun2022
36008402Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1.Nat Commun2022
35678717Activation of Tumor-Cell STING Primes NK-Cell Therapy.Cancer Immunol Res2022
36063163Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
34740862Diminished Efficacy of Programmed Death-(Ligand)1 Inhibition in STK11- and KEAP1-Mutant Lung Adenocarcinoma Is Affected by KRAS Mutation Status.J Thorac Oncol2022
34810201Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer.Cancer Res2022
35196485Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.Cell Rep2022
35101336Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
35708671Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels.JAMA Oncol2022
35678717Activation of Tumor-Cell STING Primes NK-Cell Therapy.Cancer Immunol Res2022
36063163Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
36008402Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1.Nat Commun2022
36153311Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors.Nat Commun2022
35101336Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).Genet Med2022
35196485Astrocyte-neuron crosstalk through Hedgehog signaling mediates cortical synapse development.Cell Rep2022
34810201Plasticity in the Absence of NOTCH Uncovers a RUNX2-Dependent Pathway in Small Cell Lung Cancer.Cancer Res2022
34890551Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer.Cell2021
33707236Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.Cancer Discov2021
33707234CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells.Cancer Discov2021
34890551Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer.Cell2021
33707236Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity.Cancer Discov2021
33707234CARM1 Inhibition Enables Immunotherapy of Resistant Tumors by Dual Action on Tumor Cells and T Cells.Cancer Discov2021
33060132Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production.Development2020
32098847Alterations in chromatin at antigen receptor loci define lineage progression during B lymphopoiesis.Proc Natl Acad Sci U S A2020
33060132Transcriptional regulation of MGE progenitor proliferation by PRDM16 controls cortical GABAergic interneuron production.Development2020
32098847Alterations in chromatin at antigen receptor loci define lineage progression during B lymphopoiesis.Proc Natl Acad Sci U S A2020
30872525Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.Science2019
31727771The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.Genes Dev2019
31237423Low-Input MNase Accessibility of Chromatin (Low-Input MACC).Curr Protoc Mol Biol2019
31186448Non-neutral evolution of H3.3-encoding genes occurs without alterations in protein sequence.Sci Rep2019
30872525Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate.Science2019
31123064Chromatin restriction by the nucleosome remodeler Mi-2β and functional interplay with lineage-specific transcription regulators control B-cell differentiation.Genes Dev2019
31727771The KDM5A/RBP2 histone demethylase represses NOTCH signaling to sustain neuroendocrine differentiation and promote small cell lung cancer tumorigenesis.Genes Dev2019
31186448Non-neutral evolution of H3.3-encoding genes occurs without alterations in protein sequence.Sci Rep2019
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Collaborators

Harvard Medical School
Co-authored papers 23
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University of California Berkeley
Co-authored papers 8
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Massachusetts Institute of Technology
Co-authored papers 4
Co-authored papers 4
Dana-Farber Cancer Institute
Co-authored papers 4
Co-authored papers 3
Dana-Farber Cancer Institute
Co-authored papers 3
Dana-Farber Cancer Institute
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
The University of Hong Kong
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Broad Institute of MIT and Harvard
Co-authored papers 3