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Author Details

Michael Detmar
Institute of Pharmaceutical Sciences, ETH Zurich
1986
301
93
PMIDPaper TitleJournal TitlePublished Year
36174717The p300/CBP Inhibitor A485 Normalizes Psoriatic Fibroblast Gene Expression In Vitro and Reduces Psoriasis-Like Skin Inflammation In Vivo.J Invest Dermatol2023
37043871Open pathways for cerebrospinal fluid outflow at the cribriform plate along the olfactory nerves.EBioMedicine2023
36814475Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium.Front Physiol2023
36766814Promotion of Lymphangiogenesis by Targeted Delivery of VEGF-C Improves Diabetic Wound Healing.Cells2023
33950409Mechanisms of breast cancer metastasis.Clin Exp Metastasis2022
35771983Lymphatic vessels in cancer.Physiol Rev2022
35678675Sostdc1 Secreted from Cutaneous Lymphatic Vessels Acts as a Paracrine Factor for Hair Follicle Growth.Curr Issues Mol Biol2022
35406678Novel Blood Vascular Endothelial Subtype-Specific Markers in Human Skin Unearthed by Single-Cell Transcriptomic Profiling.Cells2022
35777499Mediators of Capillary-to-Venule Conversion in the Chronic Inflammatory Skin Disease Psoriasis.J Invest Dermatol2022
36611965Antibody-Mediated Delivery of VEGF-C Promotes Long-Lasting Lymphatic Expansion That Reduces Recurrent Inflammation.Cells2022
36605202A distinct M2 macrophage infiltrate and transcriptomic profile decisively influence adipocyte differentiation in lipedema.Front Immunol2022
35892863Immunomodulatory Responses of Subcapsular Sinus Floor Lymphatic Endothelial Cells in Tumor-Draining Lymph Nodes.Cancers (Basel)2022
35131655Pheophorbide a identified in an Eupatorium perfoliatum extract is a novel lymphatic vascular activator.Biomed Pharmacother2022
34976201Non-invasive longitudinal imaging of VEGF-induced microvascular alterations in skin wounds.Theranostics2022
35147893Development of a diffusion-weighed mathematical model for intradermal drainage quantification.Drug Deliv Transl Res2022
32918672Epigenetic regulation of the lineage specificity of primary human dermal lymphatic and blood vascular endothelial cells.Angiogenesis2021
33852863CD169<sup>+</sup> lymph node macrophages have protective functions in mouse breast cancer metastasis.Cell Rep2021
33568674LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C.Nat Commun2021
33621491Beyond PROX1: transcriptional, epigenetic, and noncoding RNA regulation of lymphatic identity and function.Dev Cell2021
34699642Sialoglycans on lymphatic endothelial cells augment interactions with Siglec-1 (CD169) of lymph node macrophages.FASEB J2021
34521352The choice of negative control antisense oligonucleotides dramatically impacts downstream analysis depending on the cellular background.BMC Genom Data2021
34679571Development and Clinical Validation of the LymphMonitor Technology to Quantitatively Assess Lymphatic Function.Diagnostics (Basel)2021
33988714Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation.J Exp Med2021
34099493Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8<sup>+</sup> T-cell Responses.Cancer Res2021
34199492Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes.Cells2021
33210556Arterial Delivery of VEGF-C Stabilizes Atherosclerotic Lesions.Circ Res2021
32251437Single-cell mapping reveals new markers and functions of lymphatic endothelial cells in lymph nodes.PLoS Biol2020
32599908Keratinocyte-Expressed Podoplanin is Dispensable for Multi-Step Skin Carcinogenesis.Cells2020
32818560Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function.J Control Release2020
32585158Characterization of Tumor Blood Vasculature Expression of Human Invasive Bladder Cancer by Laser Capture Microdissection and Transcriptional Profiling.Am J Pathol2020
32307629Lymphatic MAFB regulates vascular patterning during developmental and pathological lymphangiogenesis.Angiogenesis2020
32160308Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo: authors' reply.J Physiol2020
30306266Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain.Acta Neuropathol2019
32259068Antibody-Mediated Delivery of VEGFC Ameliorates Experimental Chronic Colitis.ACS Pharmacol Transl Sci2019
31616011Lymphatic outflow of cerebrospinal fluid is reduced in glioma.Sci Rep2019
31239267Activation of the VEGFC/VEGFR3 Pathway Induces Tumor Immune Escape in Colorectal Cancer.Cancer Res2019
31344266Transcriptional profiling of breast cancer-associated lymphatic vessels reveals VCAM-1 as regulator of lymphatic invasion and permeability.Int J Cancer2019
31344105An important role of cutaneous lymphatic vessels in coordinating and promoting anagen hair follicle growth.PLoS One2019
31335913An important role of podoplanin in hair follicle growth.PLoS One2019
31189113A Distinct Role of the Autonomic Nervous System in Modulating the Function of Lymphatic Vessels under Physiological and Tumor-Draining Conditions.Cell Rep2019
30863410Inflammation and Lymphatic Function.Front Immunol2019
30829392Differential effects of anaesthesia on the contractility of lymphatic vessels in vivo.J Physiol2019
30370470AutoTube: a novel software for the automated morphometric analysis of vascular networks in tissues.Angiogenesis2019
30667371Minimally invasive method for the point-of-care quantification of lymphatic vessel function.JCI Insight2019
29650776Lymphatic exosomes promote dendritic cell migration along guidance cues.J Cell Biol2018
30242761Visualization and Measurement of Lymphatic Function In Vivo.Methods Mol Biol2018
30104684Itch suppression in mice and dogs by modulation of spinal α2 and α3GABA<sub>A</sub> receptors.Nat Commun2018
30101193Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread.Sci Adv2018
30076002Light-sheet microscopy reveals site-specific 3-dimensional patterns of the cutaneous vasculature and pronounced rarefication in aged skin.J Dermatol Sci2018
30041986Quantitative histological analyses and transcriptional profiling reveal structural and molecular changes of the dermal extracellular matrix in cellulite.J Dermatol Sci2018
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Collaborators

University of Helsinki
Co-authored papers 22
Genome Institute of Singapore (GIS)
Co-authored papers 20
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 16
Wihuri Research Institute
Co-authored papers 11
F. Hoffmann-La Roche Ltd.
Co-authored papers 9
Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 8
RIKEN Center for Integrative Medical Sciences
Co-authored papers 7
Center for Integrative Medical Sciences
Co-authored papers 7
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 6
Telethon Kids Institute, University of Western Australia
Co-authored papers 6
Cerevance Ltd
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 6
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Saint John's Cancer Institute at Saint John's Health Center
Co-authored papers 5
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 5
Ellen and Ronald Caplan Cancer Center, The Wistar Institute
Co-authored papers 5
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Child and Family Research Institute, University of British Columbia
Co-authored papers 4
Institute of Industrial Science, The University of Tokyo
Co-authored papers 4
University of Oslo
Co-authored papers 4
Karolinska Institutet at Karolinska Hospital-Huddinge
Co-authored papers 4
Mater Research Institute-University of Queensland, Translational Research Institute
Co-authored papers 4
RIKEN Center for Life Science Technologies
Co-authored papers 4
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Institute of Industrial Science, The University of Tokyo
Co-authored papers 4
Harry Perkins Institute of Medical Research
Co-authored papers 4
University of British Columbia
Co-authored papers 4