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Author Details

Yap Ching Chew
Zymo Research Corporation
2005
31
16
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36572154Nanocomplexes of doxorubicin and DNA fragments for efficient and safe cancer chemotherapy.J Control Release2023
37314333Daily SARS-CoV-2 Nasal Antigen Tests Miss Infected and Presumably Infectious People Due to Viral Load Differences among Specimen Types.Microbiol Spectr2023
36964402Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity.Geroscience2023
36926220Extreme differences in SARS-CoV-2 viral loads among respiratory specimen types during presumed pre-infectious and infectious periods.PNAS Nexus2023
36815355Reply by Authors.J Urol2023
36638792Loss of epigenetic information as a cause of mammalian aging.Cell2023
36320153Early onset of senescence and imbalanced epidermal homeostasis across the decades in photoexposed human skin: Fingerprints of inflammaging.Exp Dermatol2022
33509443DNA methylation inhibition in myeloma: Experience from a phase 1b study of low-dose continuous azacitidine in combination with lenalidomide and low-dose dexamethasone in relapsed or refractory multiple myeloma.Semin Hematol2021
33882992Clinical evaluation of Bladder CARE, a new epigenetic test for bladder cancer detection in urine samples.Clin Epigenetics2021
33082299Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer's disease.Aging (Albany NY)2020
31986014Biocompatible Chemotherapy for Leukemia by Acid-Cleavable, PEGylated FTY720.Bioconjug Chem2020
29760472Author Correction: SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.Sci Rep2018
29391557SMARCA2-regulated host cell factors are required for MxA restriction of influenza A viruses.Sci Rep2018
27769162A comparative study of ChIP-seq sequencing library preparation methods.BMC Genomics2016
23599428Protein kinase C δ increases Kruppel-like factor 4 protein, which drives involucrin gene transcription in differentiating keratinocytes.J Biol Chem2013
22427654Sulforaphane induction of p21(Cip1) cyclin-dependent kinase inhibitor expression requires p53 and Sp1 transcription factors and is p53-dependent.J Biol Chem2012
22649503Suppression of AP1 transcription factor function in keratinocyte suppresses differentiation.PLoS One2012
21085188Polycomb group proteins are key regulators of keratinocyte function.J Invest Dermatol2011
21807989Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells.Mol Pharmacol2011
21798853(-)-Epigallocatechin-3-gallate and DZNep reduce polycomb protein level via a proteasome-dependent mechanism in skin cancer cells.Carcinogenesis2011
21652709Protein kinase C (PKC) delta suppresses keratinocyte proliferation by increasing p21(Cip1) level by a KLF4 transcription factor-dependent mechanism.J Biol Chem2011
20357078Biotin requirements are lower in human Jurkat lymphoid cells but homeostatic mechanisms are similar to those of HepG2 liver cells.J Nutr2010
20445555PKC-delta and -eta, MEKK-1, MEK-6, MEK-3, and p38-delta are essential mediators of the response of normal human epidermal keratinocytes to differentiating agents.J Invest Dermatol2010
19812216Repression of transposable elements by histone biotinylation.J Nutr2009
18287656Use of synthetic peptides for identifying biotinylation sites in human histones.Methods Mol Biol2008
19022951Biotinylation of histones represses transposable elements in human and mouse cells and cell lines and in Drosophila melanogaster.J Nutr2008
18673490Epigenetic regulation of chromatin structure and gene function by biotin: are biotin requirements being met?Nutr Rev2008
17156993An avidin-based assay for histone debiotinylase activity in human cell nuclei.J Nutr Biochem2007
16109483Lysine residues in N-terminal and C-terminal regions of human histone H2A are targets for biotinylation by biotinidase.J Nutr Biochem2006
15992689Biological functions of biotinylated histones.J Nutr Biochem2005
15867268Riboflavin deficiency impairs oxidative folding and secretion of apolipoprotein B-100 in HepG2 cells, triggering stress response systems.J Nutr2005
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Collaborators

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Institute of Virology, Medical Center University of Freiburg
Co-authored papers 2
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Northwestern University Feinberg School of Medicine
Co-authored papers 2
Institute of Virology, Medical Center - University of Freiburg
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Brigham and Women's Hospital
Co-authored papers 1
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Brigham and Women's Hospital (Y.K.
Co-authored papers 1
Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 1
University of Nebraska Medical Center
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Harvard Medical School
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University of Mississippi Medical Center
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California Institute of Technology
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Center for Cancer Research, Massachusetts General Hospital, Harvard Medical School
Co-authored papers 1