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Author Details

Christopher J Lessard
2007
60
31
PMIDPaper TitleJournal TitlePublished Year
36869684Identification of new candidate drugs for primary Sjögren's syndrome using a drug repurposing transcriptomic approach.Rheumatology (Oxford)2023
36649279Ancestral origins are associated with SARS-CoV-2 susceptibility and protection in a Florida patient population.2023
37147113Autoantibodies identify primary Sjögren's syndrome in patients lacking serum IgG specific for Ro/SS-A and La/SS-B.Ann Rheum Dis2023
36702181Anti-vimentin antibodies are associated with higher severity of Sjögren's disease.2023
36456101Dysregulated long non-coding RNA in Sjögren's disease impacts both interferon and adaptive immune responses.RMD Open2022
35726083Variability of Primary Sjögren's Syndrome Is Driven by Interferon-α and Interferon-α Blood Levels Are Associated With the Class II HLA-DQ Locus.Arthritis Rheumatol2022
34907023Genetic variants at the locus are associated with fatigue in Scandinavian patients with primary Sjögren's syndrome.RMD Open2021
33488608Transcriptomic and Network Analysis of Minor Salivary Glands of Patients With Primary Sjögren's Syndrome.Front Immunol2021
34575873Defective Efferocytosis in a Murine Model of Sjögren's Syndrome Is Mediated by Dysfunctional Mer Tyrosine Kinase Receptor.International Journal of Molecular Sciences2021
31199565American Indians Have a Higher Risk of Sjögren's Syndrome and More Disease Activity Than European Americans and African Americans.Arthritis Care and Research2020
32201227Gene expression profiling of epithelium-associated FcRL4<sup>+</sup> B cells in primary Sjögren's syndrome reveals a pathogenic signature.J Autoimmun2020
32650575Sjögren's Syndrome Minor Salivary Gland CD4<sup>+</sup> Memory T Cells Associate with Glandular Disease Features and have a Germinal Center T Follicular Helper Transcriptional Profile.J Clin Med2020
32503977Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica.Nat Commun2020
31092717Sjögren Syndrome without Focal Lymphocytic Infiltration of the Salivary Glands.Journal of Rheumatology2020
31453437Reproducibility of Ocular Surface Staining in the Assessment of Sjögren Syndrome-Related Keratoconjunctivitis Sicca: Implications on Disease Classification.ACR Open Rheumatol2019
29148407Minor salivary gland fibrosis in Sjögren's syndrome is elevated, associated with focus score and not solely a consequence of aging.Clinical and Experimental Rheumatology2018
29457375Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren's Syndrome.Arthritis and Rheumatology2018
29195081Corrigendum to "Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome" [Clin. Immunol. 168 (2016) 25-29].Clin Immunol2018
28275240Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry.Genes and Immunity2017
28692793Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome.Arthritis Rheumatol2017
28640813Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.PLoS Genet2017
28988489Fatty infiltration of the minor salivary glands is a selective feature of aging but not Sjögren's syndrome.Autoimmunity2017
28166540Effect of Tobacco Smoking on The Clinical, Histopathological, and Serological Manifestations of Sjögren's Syndrome.PLoS ONE2017
28135245A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases.Nature Genetics2017
26663301Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.Arthritis Rheumatol2016
26894205Cytokine profiles show heterogeneity of interferon-β response in multiple sclerosis patients.Neurology: Neuroimmunology and NeuroInflammation2016
27109640Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome.Clin Immunol2016
27431346Genetics in Sjögren Syndrome.Rheumatic Disease Clinics of North America2016
26998859Previous diagnosis of Sjögren's Syndrome as rheumatoid arthritis or systemic lupus erythematosus.Rheumatology2016
27358913Single-cell analysis of glandular T cell receptors in Sjögren's syndrome.JCI insight2016
26713507X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.Arthritis Rheumatol2016
26636433Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity.Arthritis Rheumatol2016
26338037Germline variation of TNFAIP3 in primary Sjögren's syndrome-associated lymphoma.Annals of the Rheumatic Diseases2016
25205108The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.Hum Mol Genet2015
26423047Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data.BMC Bioinformatics2015
24702955Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.Am J Hum Genet2014
23968620Comparison of the American-European Consensus Group Sjogren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort.Ann Rheum Dis2014
25199908Antibody-secreting cell specificity in labial salivary glands reflects the clinical presentation and serology in patients with Sjögren's syndrome.Arthritis and Rheumatology2014
23884468NCR3/NKp30 contributes to pathogenesis in primary Sjogren's syndrome.Science Translational Medicine2013
23819992Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome.2013
24159176Germline and somatic genetic variations of TNFAIP3 in lymphoma complicating primary Sjogren's syndrome.Blood2013
24062752Interferons in Sjögren's Syndrome: Genes, Mechanisms, and Effects.Frontiers in Immunology2013
24097067Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.Nat Genet2013
22189356Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.Genes Immun2012
22476155A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.Genes Immun2012
22289719Genetics of Sjögren's syndrome in the genome-wide association era.Journal of Autoimmunity2012
22833143Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.Arthritis Rheum2012
22464253Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.Am J Hum Genet2012
22955477Relation of sensory peripheral neuropathy in Sjögren syndrome to anti-Ro/SSA.J Clin Rheumatol2012
22952805Genome-wide association study of African and European Americans implicates multiple shared and ethnic specific loci in sarcoidosis susceptibility.PLoS One2012
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