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Author Details

Simon N Powell
Memorial Sloan Kettering Cancer Center
1990
230
67
PMIDPaper TitleJournal TitlePublished Year
37748124Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial.J Clin Oncol2024
36155213Outcomes of Breast Cancer Patients with High Volume of Residual Disease Following Neoadjuvant Chemotherapy.Int J Radiat Oncol Biol Phys2023
37591896Genomic analysis and clinical correlations of non-small cell lung cancer brain metastasis.Nat Commun2023
37587346Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers.Nature2023
37945902Most large structural variants in cancer genomes can be detected without long reads.Nat Genet2023
37612508Non-cell-autonomous cancer progression from chromosomal instability.Nature2023
37647215A local ATR-dependent checkpoint pathway is activated by a site-specific replication fork block in human cells.Elife2023
38047221A Potential Pitfall and Clinical Solutions in Surface-Guided Deep Inspiration Breath Hold Radiation Therapy for Left-Sided Breast Cancer.Adv Radiat Oncol2023
37535396Comparison of setup accuracy of optical surface image versus orthogonal x-ray images for VMAT of the left breast using deep-inspiration breath-hold.J Appl Clin Med Phys2023
36993263A local ATR-dependent checkpoint pathway is activated by a site-specific replication fork block in human cells.bioRxiv2023
37250283Locoregional Control Benefit of a Tumor Bed Boost for Ductal Carcinoma In Situ.Adv Radiat Oncol2023
37244631Activation of STING in Response to Partial-Tumor Radiation Exposure.Int J Radiat Oncol Biol Phys2023
36976395Metaplastic carcinoma of the breast: matched cohort analysis of recurrence and survival.Breast Cancer Res Treat2023
37305071Accelerated Partial Breast Irradiation: Association of Dosimetric Parameters With Patient-Reported Outcomes.Adv Radiat Oncol2023
37333127Regional nodal irradiation for breast cancer using volumetric modulated arc therapy: Echocardiographic functional outcomes.Res Sq2023
36896216Accuracy and Efficiency of Patient Setup Using Surface Imaging versus Skin Tattoos for Accelerated Partial Breast Irradiation.Adv Radiat Oncol2023
36449664Dynamic Mutational Landscape of Cerebrospinal Fluid Circulating Tumor DNA and Predictors of Survival after Proton Craniospinal Irradiation for Leptomeningeal Metastases.Clin Cancer Res2023
35993318Reproducibility of chestwall and heart position using surface-guided versus RPM-guided DIBH radiotherapy for left breast cancer.J Appl Clin Med Phys2023
35049108A uniform and versatile surface-guided radiotherapy procedure and workflow for high-quality breast deep-inspiration breath-hold treatment in a multi-center institution.J Appl Clin Med Phys2022
35802849Randomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis.J Clin Oncol2022
35688528Harnessing the DNA Repair Pathway in Breast Cancer: Germline Mutations/Polymorphisms in Breast Radiation.Semin Radiat Oncol2022
35713598A multi-institutional prediction model to estimate the risk of recurrence and mortality after mastectomy for T1-2N1 breast cancer.Cancer2022
35385581Templated Insertions Are Associated Specifically with BRCA2 Deficiency and Overall Survival in Advanced Ovarian Cancer.Mol Cancer Res2022
35045364Bilateral Regional Nodal Irradiation Using Volumetric Modulated Arc Therapy: Dosimetric Analysis and Feasibility.Pract Radiat Oncol2022
35092538Examining the prevalence of homologous recombination repair defects in ER+â¿¿breast cancers.Breast Cancer Res Treat2022
34937945HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51.Nature2022
34928169Replication Protein A Phosphorylation Facilitates RAD52-Dependent Homologous Recombination in BRCA-Deficient Cells.Mol Cell Biol2022
32726432Pathogenic ATM Mutations in Cancer and a Genetic Basis for Radiotherapeutic Efficacy.J Natl Cancer Inst2021
33770311Salvage of locally recurrent breast cancer with repeat breast conservation using 45 Gy hyperfractionated partial breast re-irradiation.Breast Cancer Res Treat2021
33795234Synthetic Lethality in Cancer Therapeutics: The Next Generation.Cancer Discov2021
33877327Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell.Nucleic Acids Res2021
33788624Novel Inpatient Radiation Oncology Consult Service Model Reduces Hospital Length of Stay.JCO Oncol Pract2021
33834176Mutations in <i>BRCA1</i> and <i>BRCA2</i> differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy.Nat Cancer2021
33496354Breast conservation among older patients with early-stage breast cancer: Locoregional recurrence following adjuvant radiation or hormonal therapy.Cancer2021
34635660Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination.NPJ Breast Cancer2021
34688807Proton reirradiation for recurrent or new primary breast cancer in the setting of prior breast irradiation.Radiother Oncol2021
33941615Disabling the Fanconi Anemia Pathway in Stem Cells Leads to Radioresistance and Genomic Instability.Cancer Res2021
34250389Tolerability of Breast Radiotherapy Among Carriers of <i>ATM</i> Germline Variants.JCO Precis Oncol2021
34089683In Reply to Rans et al.Int J Radiat Oncol Biol Phys2021
34140615Perineural invasion as a risk factor for locoregional recurrence of invasive breast cancer.Sci Rep2021
33372007Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.Cancer Discov2021
3337196410-Year Breast Cancer Outcomes in Women ⿤35 Years of Age.Int J Radiat Oncol Biol Phys2021
33429428Precision Radiotherapy: Reduction in Radiation for Oropharyngeal Cancer in the 30 ROC Trial.J Natl Cancer Inst2021
33422612Phase 3 Multi-Center, Prospective, Randomized Trial Comparing Single-Dose 24 Gy Radiation Therapy to a 3-Fraction SBRT Regimen in the Treatment of Oligometastatic Cancer.Int J Radiat Oncol Biol Phys2021
33477018Homologous recombination deficiency: how genomic signatures are generated.Curr Opin Genet Dev2021
33449096Accuracy of Magnetic Resonance Imaging-Guided Biopsy to Verify Breast Cancer Pathologic Complete Response After Neoadjuvant Chemotherapy: A Nonrandomized Controlled Trial.JAMA Netw Open2021
32292842Breast Radiation Therapy Under COVID-19 Pandemic Resource Constraints-Approaches to Defer or Shorten Treatment From a Comprehensive Cancer Center in the United States.Adv Radiat Oncol2020
32023457A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability.Cell Rep2020
31747077A phase 2 clinical trial⿯assessing the⿯efficacy and safety of pembrolizumab and radiotherapy in patients with metastatic triple-negative breast cancer.Cancer2020
32006728Feasibility of Breast-Conservation Therapy and Hypofractionated Radiation in the Setting of Prior Breast Augmentation.Pract Radiat Oncol2020
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Collaborators

Memorial Sloan Kettering Cancer Center
Co-authored papers 25
Memorial Sloan Kettering Cancer Center
Co-authored papers 22
Memorial Sloan-Kettering Cancer Center
Co-authored papers 18
Memorial Sloan Kettering Cancer Center
Co-authored papers 15
Memorial Sloan Kettering Cancer Center
Co-authored papers 12
Memorial Sloan Kettering Cancer Center
Co-authored papers 9
Memorial Sloan Kettering Cancer Center
Co-authored papers 9
Memorial Sloan Kettering Cancer Center
Co-authored papers 6
Cleveland Clinic.
Co-authored papers 5
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Yale University School of Medicine
Co-authored papers 5
Massachusetts General Hospital
Co-authored papers 5
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Meyer Cancer Center
Co-authored papers 4
Kasturba Medical College, Manipal Academy of Higher Education (MAHE)
Co-authored papers 4
University of Toronto
Co-authored papers 4
Co-authored papers 4
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Co-authored papers 4
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
The Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Memorial Sloan Kettering Cancer Center, USA American Society of Clinical Oncology
Co-authored papers 3
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3