Author details

Full Name

Gavin Lucas

Affiliation

ORCID

Career Start Year

2002

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
29170203	Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.	Ann Rheum Dis	2018
27103211	Cardiovascular Risk Factors and Ischemic Heart Disease: Is the Confluence of Risk Factors Greater Than the Parts? A Genetic Approach.	Circulation: Cardiovascular Genetics	2016
25658981	Analysis of gene-gene interactions among common variants in candidate cardiovascular genes in coronary artery disease.	PLoS ONE	2015
25709812	Big data challenges in bone research: genome-wide association studies and next-generation sequencing.		2015
24954895	Gene-age interactions in blood pressure regulation: a large-scale investigation with the CHARGE, Global BPgen, and ICBP Consortia.	Am J Hum Genet	2014
24520200	Pathogenesis of coronary artery disease: focus on genetic risk factors and identification of genetic variants.	Application of Clinical Genetics	2014
23585847	DNA isolation method is a source of global DNA methylation variability measured with LUMA. Experimental analysis and a systematic review.	PLoS ONE	2013
21693476	Meta-analyses of the association between cytochrome CYP2C19 loss- and gain-of-function polymorphisms and cardiovascular outcomes in patients with coronary artery disease treated with clopidogrel.	Heart	2012
22479202	Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.	PLoS Genet	2012
22876292	Hypothesis-based analysis of gene-gene interactions and risk of myocardial infarction.	PLoS One	2012
22521901	Assessment of the value of a genetic risk score in improving the estimation of coronary risk.	Atherosclerosis	2012
21984528	Post-genomic update on a classical candidate gene for coronary artery disease: ESR1.	Circ Cardiovasc Genet	2011
21427121	A gain-of-function SNP in TRPC4 cation channel protects against myocardial infarction.	Cardiovasc Res	2011
21609482	CNVassoc: Association analysis of CNV data using R.	BMC Medical Genomics	2011
21909115	Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.	Nature	2011
21909110	Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.	Nat Genet	2011
20933357	Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies.	J Am Coll Cardiol	2010
21082022	Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.	PLoS Genet	2010
20738937	Additive effect of multiple genetic variants on the risk of coronary artery disease.	Revista Espanola de Cardiologia	2010
20686565	Biological, clinical and population relevance of 95 loci for blood lipids.	Nature	2010
19608186	Qualitative assessment of previous evidence and an updated meta-analysis confirms lack of association between the ESR1 rs2234693 (PvuII) variant and coronary heart disease in men and women.	Atherosclerosis	2009
19430483	Genome-wide association study identifies eight loci associated with blood pressure.	Nat Genet	2009
19198609	Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.	Nat Genet	2009
17907922	Identification of a major locus for Paget's disease on chromosome 10p13 in families of British descent.	Journal of Bone and Mineral Research	2008
17229006	Contribution of genetic factors to the pathogenesis of Paget's disease of bone and related disorders.	Journal of Bone and Mineral Research	2006
16199218	Evaluation of the role of Valosin-containing protein in the pathogenesis of familial and sporadic Paget's disease of bone.	Bone	2006
15647816	Ubiquitin-associated domain mutations of SQSTM1 in Paget's disease of bone: evidence for a founder effect in patients of British descent.	Journal of Bone and Mineral Research	2005
15176995	Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences.	Journal of Bone and Mineral Research	2004
12374763	Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease.	Human Molecular Genetics	2002