Author details

Full Name

Todd J Suscovich

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37061918	Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates.	Cell Rep	2023
35348368	mRNA-1273 and BNT162b2 COVID-19 vaccines elicit antibodies with differences in Fc-mediated effector functions.	Sci Transl Med	2022
35657812	Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeutics.	PLoS ONE	2022
34494026	Subtle immunological differences in mRNA-1273 and BNT162b2 COVID-19 vaccine induced Fc-functional profiles.	bioRxiv	2021
35590199	Delayed fractional dosing with RTS,S/AS01 improves humoral immunity to malaria via a balance of polyfunctional NANP6- and Pf16-specific antibodies.	Med	2021
33852832	A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus.	Immunity	2021
33983379	Immunogenicity of COVID-19 mRNA Vaccines in Pregnant and Lactating Women.	JAMA	2021
33427208	Dissecting strategies to tune the therapeutic potential of SARS-CoV-2-specific monoclonal antibody CR3022.	JCI Insight	2021
31301137	Survivors of Ebola Virus Disease Develop Polyfunctional Antibody Responses.	J Infect Dis	2020
33048992	Mining for humoral correlates of HIV control and latent reservoir size.	PLoS Pathog	2020
32747832	Integrated pipeline for the accelerated discovery of antiviral antibody therapeutics.	Nat Biomed Eng	2020
32783920	Distinct Early Serological Signatures Track with SARS-CoV-2 Survival.	Immunity	2020
33007262	Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques.	Cell	2020
33326789	HIV Antibody Fc N-Linked Glycosylation Is Associated with Viral Rebound.	Cell Rep	2020
32718991	Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination.	Sci Transl Med	2020
31204102	Fc Glycan-Mediated Regulation of Placental Antibody Transfer.	Cell	2019
30659065	Multi-isotype Glycoproteomic Characterization of Serum Antibody Heavy Chains Reveals Isotype- and Subclass-Specific N-Glycosylation Profiles.	Mol Cell Proteomics	2019
31301278	A high-throughput, bead-based, antigen-specific assay to assess the ability of antibodies to induce complement activation.	Journal of Immunological Methods	2019
31132351	A versatile high-throughput assay to characterize antibody-mediated neutrophil phagocytosis.	Journal of Immunological Methods	2019
31222179	Publisher Correction: IFN-Î³-independent immune markers of Mycobacterium tuberculosis exposure.	Nat Med	2019
29677181	Exploiting glycan topography for computational design of Env glycoprotein antigenicity.	PLoS Comput Biol	2018
30120121	Antigen-specific antibody Fc glycosylation enhances humoral immunity via the recruitment of complement.	Sci Immunol	2018
30092199	A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.	Cell Host Microbe	2018
30177821	Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV.	Nat Med	2018
29239894	Temporal variation in HIV-specific IgG subclass antibodies during acute infection differentiates spontaneous controllers from chronic progressors.	AIDS	2018
29581149	High-resolution definition of humoral immune response correlates of effective immunity against HIV.	Mol Syst Biol	2018
29063907	Beyond binding: antibody effector functions in infectious diseases.	Nature Reviews Immunology	2018
28158448	Virus-driven Inflammation Is Associated With the Development of bNAbs in Spontaneous Controllers of HIV.	Clin Infect Dis	2017
28593989	Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge.	Nature Communications	2017
27667685	A Functional Role for Antibodies in Tuberculosis.	Cell	2016
26883728	Fc receptor-mediated phagocytosis in tissues as a potent mechanism for preventive and therapeutic HIV vaccine strategies.	Mucosal Immunol	2016
26745376	Polyfunctional HIV-Specific Antibody Responses Are Associated with Spontaneous HIV Control.	PLoS Pathog	2016
26960182	Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16.	Mucosal Immunol	2016
27253391	Correction: Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination.	PLoS Pathog	2016
26982805	Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination.	PLoS Pathog	2016
26565674	Broadly Neutralizing Antibodies Against HIV: New Insights to Inform Vaccine Design.	Annual Review of Medicine	2016
27521484	HLA-C levels impact natural killer cell subset distribution and function.	Hum Immunol	2016
26544943	Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology.	Cell	2015
25874406	Machine learning methods enable predictive modeling of antibody feature:function relationships in RV144 vaccinees.	PLoS Computational Biology	2015
25578347	In situ production of therapeutic monoclonal antibodies.	Expert Review of Vaccines	2015
25523925	A method for high-throughput, sensitive analysis of IgG Fc and Fab glycosylation by capillary electrophoresis.	J Immunol Methods	2015
25043633	Independent evolution of Fc- and Fab-mediated HIV-1-specific antiviral antibody activity following acute infection.	European Journal of Immunology	2014
24352471	Divergent antibody subclass and specificity profiles but not protective HLA-B alleles are associated with variable antibody effector function among HIV-1 controllers.	Journal of Virology	2014
24820481	Lack of protection following passive transfer of polyclonal highly functional low-dose non-neutralizing antibodies.	PLoS ONE	2014
24648341	Polyfunctional Fc-effector profiles mediated by IgG subclass selection distinguish RV144 and VAX003 vaccines.	Science Translational Medicine	2014
24785948	Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03:04 and modulate primary natural killer cell function.	AIDS	2014
23135171	Decoupling activation and exhaustion of B cells in spontaneous controllers of HIV infection.	AIDS	2013
22740092	Type-1 immunity drives early lethality in scurfy mice.	European Journal of Immunology	2012
21471235	Receptor-ligand requirements for increased NK cell polyfunctional potential in slow progressors infected with HIV-1 coexpressing KIR3DL1h/y and HLA-B*57.	J Virol	2011
18317010	Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands.	AIDS	2008