Author details

Full Name

John A Alberta

Affiliation

ORCID

Career Start Year

1987

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
31427603	Mitogenic and progenitor gene programmes in single pilocytic astrocytoma cells.	Nat Commun	2019
29760046	Dual HDAC and PI3K Inhibition Abrogates NFÎºB- and FOXM1-Mediated DNA Damage Response to Radiosensitize Pediatric High-Grade Gliomas.	Cancer Res	2018
28177281	Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability.	Elife	2017
28614724	Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-Î² Pathway.	Cell Rep	2017
28355568	A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2.	Cell Rep	2017
28082416	A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas.	Neuro Oncol	2017
27643505	Challenges in Targeting a Basic Helix-Loop-Helix Transcription Factor with Hydrocarbon-Stapled Peptides.	ACS Chemical Biology	2016
27396340	Post-translational Modifications of OLIG2 Regulate Glioma Invasion through the TGF-Î² Pathway.	Cell Rep	2016
24948806	An amino terminal phosphorylation motif regulates intranuclear compartmentalization of Olig2 in neural progenitor cells.	J Neurosci	2014
24507192	Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain.	Neuron	2014
24091529	Molecular imaging of drug transit through the blood-brain barrier with MALDI mass spectrometry imaging.	Sci Rep	2013
22474248	C/EBPÎ± and DEK coordinately regulate myeloid differentiation.	Blood	2012
21382551	Phosphorylation state of Olig2 regulates proliferation of neural progenitors.	Neuron	2011
21397859	The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma.	Cancer Cell	2011
17482130	Synergy between PPARgamma ligands and platinum-based drugs in cancer.	Cancer Cell	2007
17296553	Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.	Neuron	2007
16682644	Development of NG2 neural progenitor cells requires Olig gene function.	Proc Natl Acad Sci U S A	2006
15800203	Microanatomy of axon/glial signaling during Wallerian degeneration.	Journal of Neuroscience	2005
15389679	Distinct temporal genetic signatures of neurogenic and gliogenic cues in cortical stem cell cultures.		2005
15198128	The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas.	J Neuropathol Exp Neurol	2004
15604411	bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.	Science	2004
15618518	Mouse brain organization revealed through direct genome-scale TF expression analysis.	Science	2004
15063178	Wt1 functions in the development of germ cells in addition to somatic cell lineages of the testis.	Developmental Biology	2004
14643017	Expression of the guanine nucleotide exchange factor, mr-gef, is regulated during the differentiation of specific subsets of telencephalic neurons.	Developmental Brain Research	2003
12468434	Role of the WT1 tumor suppressor in murine hematopoiesis.	Blood	2003
12024052	A mammal-specific exon of WT1 is not required for development or fertility.	Molecular and Cellular Biology	2002
11526205	Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors.	Proc Natl Acad Sci U S A	2001
18428463	Generation and utilization of phosphorylation state-specific antibodies to investigate signaling pathways.	Current Protocols in Neuroscience	2001
11640898	Sonic hedgehog is required during an early phase of oligodendrocyte development in mammalian brain.	Mol Cell Neurosci	2001
10719888	Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system.	Neuron	2000
11016641	Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.	Cancer Res	2000
10521506	Platelet-derived growth factor stimulation of monocyte chemoattractant protein-1 gene expression is mediated by transient activation of the phosphoinositide 3-kinase signal transduction pathway.	Journal of Biological Chemistry	1999
9931326	PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies.	Hum Mol Genet	1999
10575035	Bipotent cortical progenitor cells process conflicting cues for neurons and glia in a hierarchical manner.	Journal of Neuroscience	1999
9136765	A PDGF-regulated immediate early gene response initiates neuronal differentiation in ventricular zone progenitor cells.	Neuron	1997
9334404	Activation of ErbB2 during wallerian degeneration of sciatic nerve.	J Neurosci	1997
9307305	Detection of activated platelet-derived growth factor receptors in human meningioma.	Cancer Res	1997
9298221	Phosphorylation-directed antibodies in high-flux screens for compounds that modulate signal transduction.	BioTechniques	1997
8663287	Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-kappaB and a 90-kDa phosphoprotein coactivator.	Journal of Biological Chemistry	1996
8702742	Differential utilization of Trk autophosphorylation sites.	J Biol Chem	1996
7702835	Electroporation of peptides into adherent cells in situ.	Biotechniques	1995
7799939	A new platelet-derived growth factor-regulated genomic element which binds a serine/threonine phosphoprotein mediates induction of the slow immediate-early gene MCP-1.	Molecular and Cellular Biology	1995
8556428	Applications of electroporation of adherent cells in situ, on a partly conductive slide.	Mol Biotechnol	1995
8182075	Multiple, functional DBP sites on the promoter of the cholesterol 7 alpha-hydroxylase P450 gene, CYP7. Proposed role in diurnal regulation of liver gene expression.	Journal of Biological Chemistry	1994
8308023	Identification of an activity that interacts with the 3'-untranslated region of c-myc mRNA and the role of its target sequence in mediating rapid mRNA degradation.	Journal of Biological Chemistry	1994
1740438	Sex-specific, growth hormone-regulated transcription of the cytochrome P450 2C11 and 2C12 genes.	Journal of Biological Chemistry	1992
2342479	Pituitary regulation of the male-specific steroid 6 beta-hydroxylase P-450 2a (gene product IIIA2) in adult rat liver. Suppressive influence of growth hormone and thyroxine acting at a pretranslational leve;.	Molecular Endocrinology	1990
2917992	The platelet-derived growth factor-inducible KC gene encodes a secretory protein related to platelet alpha-granule proteins.	Journal of Biological Chemistry	1989
2544848	Labile repressors are involved in the transcriptional control of PDGF-responsive genes.		1989
2547595	Subcellular localization of a protein produced in adrenal cortex cells in response to ACTH.	Endocrine Research	1989