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Author Details

David C Smith
Rogel Comprehensive Cancer Center, University of Michigan ann arbor
1985
154
55
PMIDPaper TitleJournal TitlePublished Year
36317715A Phase 2 Trial of Nab-paclitaxel in Combination With Anti-PD1 Therapy in Advanced Urothelial Cancer.J Urol2023
37385724Phase 1 dose-escalation study of SEA-CD40: a non-fucosylated CD40 agonist, in advanced solid tumors and lymphomas.J Immunother Cancer2023
36959716Outpatient administration of paclitaxel, ifosfamide, and cisplatin (TIP) for germ cell tumor.J Oncol Pharm Pract2023
36787089First-in-Human Study of INCB062079, a Fibroblast Growth Factor Receptor 4 Inhibitor, in Patients with Advanced Solid Tumors.Target Oncol2023
36750016Survival, Durable Tumor Remission, and Long-Term Safety in Patients With Advanced Melanoma Receiving Nivolumab.J Clin Oncol2023
35176457FIGHT-101, a first-in-human study of potent and selective FGFR 1-3 inhibitor pemigatinib in pan-cancer patients with FGF/FGFR alterations and advanced malignancies.Ann Oncol2022
35472327Prostate Cancer With Peritoneal Carcinomatosis: A Robotic-assisted Radical Prostatectomy-based Case Series.Urology2022
33941878Phase 1 study of single-agent WNT974, a first-in-class Porcupine inhibitor, in patients with advanced solid tumours.Br J Cancer2021
33630025Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.JAMA Oncol2021
33617303TRANSFORMER: A Randomized Phase II Study Comparing Bipolar Androgen Therapy Versus Enzalutamide in Asymptomatic Men With Castration-Resistant Metastatic Prostate Cancer.J Clin Oncol2021
35008431Multigene Profiling of Circulating Tumor Cells (CTCs) for Prognostic Assessment in Treatment-Naïve Metastatic Hormone-Sensitive Prostate Cancer (mHSPC).Int J Mol Sci2021
31527168Development of 2 Bromodomain and Extraterminal Inhibitors With Distinct Pharmacokinetic and Pharmacodynamic Profiles for the Treatment of Advanced Malignancies.Clin Cancer Res2020
32031899EV-101: A Phase I Study of Single-Agent Enfortumab Vedotin in Patients With Nectin-4-Positive Solid Tumors, Including Metastatic Urothelial Carcinoma.J Clin Oncol2020
32913286Phase 1 study of mTORC1/2 inhibitor sapanisertib (TAK-228) in advanced solid tumours, with an expansion phase in renal, endometrial or bladder cancer.Br J Cancer2020
32299729Efficacy and Effect of Cabozantinib on Bone Metastases in Treatment-naive Castration-resistant Prostate Cancer.Clin Genitourin Cancer2020
30591982A phase 1 dose escalation and expansion study of Tarextumab (OMP-59R5) in patients with solid tumors.Invest New Drugs2019
31805523Testicular Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.J Natl Compr Canc Netw2019
31853198First-In-Human Phase I Study Of A Dual mTOR Kinase And DNA-PK Inhibitor (CC-115) In Advanced Malignancy.Cancer Manag Res2019
30132271A phase 1 trial of SGN-CD70A in patients with CD70-positive diffuse large B cell lymphoma and mantle cell lymphoma.Invest New Drugs2019
30229512A first-in-human phase 1a study of the bispecific anti-DLL4/anti-VEGF antibody navicixizumab (OMP-305B83) in patients with previously treated solid tumors.Invest New Drugs2019
31023520Cardiovascular and Metabolic Toxicity of Abiraterone in Castration-resistant Prostate Cancer: Post-marketing Experience.Clin Genitourin Cancer2019
30624766A phase 1 trial of SGN-CD70A in patients with CD70-positive, metastatic renal cell carcinoma.Cancer2019
29236570Streamlining Adverse Events Reporting in Oncology: An American Society of Clinical Oncology Research Statement.J Clin Oncol2018
30192374Castration remains despite decreasing definitive treatment of localized prostate cancer in the elderly: A case for de-implementation.Cancer2018
30042870Multimodal imaging provides insight into targeted therapy response in metastatic prostate cancer to the bone.Am J Nucl Med Mol Imaging2018
30265610Epacadostat Plus Pembrolizumab in Patients With Advanced Solid Tumors: Phase I Results From a Multicenter, Open-Label Phase I/II Trial (ECHO-202/KEYNOTE-037).J Clin Oncol2018
30693182Detection of CTC Clusters and a Dedifferentiated RNA-Expression Survival Signature in Prostate Cancer.Adv Sci (Weinh)2018
29570421Five-Year Follow-Up of Nivolumab in Previously Treated Advanced Non-Small-Cell Lung Cancer: Results From the CA209-003 Study.J Clin Oncol2018
29453313Multigene Profiling of CTCs in mCRPC Identifies a Clinically Relevant Prognostic Signature.Mol Cancer Res2018
29261439Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012.J Clin Oncol2018
28783718Integrative clinical genomics of metastatic cancer.Nature2017
28314841Academic Cancer Center Phase I Program Development.Oncologist2017
28242752Phase I, Dose-Escalation, Two-Part Trial of the PARP Inhibitor Talazoparib in Patients with Advanced Germline <i>BRCA1/2</i> Mutations and Selected Sporadic Cancers.Cancer Discov2017
29059635Phase II randomised discontinuation trial of cabozantinib in patients with advanced solid tumours.Eur J Cancer2017
28954784A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors.Clin Cancer Res2017
29163793Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy.Oncotarget2017
28755607A phase 2 randomised discontinuation trial of cabozantinib in patients with ovarian carcinoma.Eur J Cancer2017
26984445Electrocardiographic Characterization of Ramucirumab on the Corrected QT Interval in a Phase II Study of Patients With Advanced Solid Tumors.Oncologist2016
26576779First-in-human multicenter phase I study of BMS-936561 (MDX-1203), an antibody-drug conjugate targeting CD70.Cancer Chemother Pharmacol2016
27379498Lack of pharmacokinetic drug-drug interaction between ramucirumab and paclitaxel in a phase II study of patients with advanced malignant solid tumors.Cancer Chemother Pharmacol2016
27312733Evaluation of the effect of necitumumab on the corrected QT interval in patients with advanced solid tumors.Cancer Chemother Pharmacol2016
26806347Mechanistic Support for Combined MET and AR Blockade in Castration-Resistant Prostate Cancer.Neoplasia2016
24631409Effects of cabozantinib on pain and narcotic use in patients with castration-resistant prostate cancer: results from a phase 2 nonrandomized expansion cohort.Eur Urol2015
28799570A phase 2 trial of salvage radiation and concurrent weekly docetaxel after a rising prostate-specific antigen level after radical prostatectomy.Adv Radiat Oncol2015
28843286Integrative Clinical Genomics of Advanced Prostate Cancer.Cell2015
26281907A phase I open-label trial evaluating the cardiovascular safety of regorafenib in patients with advanced cancer.Cancer Chemother Pharmacol2015
25897158Overall Survival and Long-Term Safety of Nivolumab (Anti-Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non-Small-Cell Lung Cancer.J Clin Oncol2015
26000489Integrative clinical genomics of advanced prostate cancer.Cell2015
25716544Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: results of a first-in-man study.Cancer Chemother Pharmacol2015
25777468Phase 1 study of ixazomib, an investigational proteasome inhibitor, in advanced non-hematologic malignancies.Invest New Drugs2015
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Collaborators

The Brady Urological Institute, Johns Hopkins University School of Medicine
Co-authored papers 33
Northwestern University
Co-authored papers 32
Duke University School of Medicine, and the Duke Cancer Institute
Co-authored papers 11
University of Michigan Medical School.
Co-authored papers 10
Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center
Co-authored papers 9
Michigan Center for Translational Pathology.
Co-authored papers 8
Michigan Center for Translational Pathology, University of Michigan ann arbor
Co-authored papers 8
Michigan Center for Translational Pathology, University of Michigan ann arbor
Co-authored papers 7
Memorial Sloan Kettering Cancer Center
Co-authored papers 7
UCSF Medical Center-Mount Zion
Co-authored papers 7
Rogel Cancer Center, University of Michigan Medical School ann arbor
Co-authored papers 7
University of California san francisco
Co-authored papers 7
University of Michigan ann arbor
Co-authored papers 6
Memorial Sloan Kettering Cancer Center
Co-authored papers 6
Michigan Center for Translational Pathology.
Co-authored papers 6
Michigan Center for Translational Pathology, University of Michigan ann arbor
Co-authored papers 6
Michigan Center for Translational Pathology, University of Michigan ann arbor
Co-authored papers 6
University of Michigan Medical School ann arbor
Co-authored papers 6
University of Michigan Rogel Cancer Center.
Co-authored papers 5
The Institute for Cancer Research
Co-authored papers 5
Sandra and Edward Meyer Cancer Center
Co-authored papers 5
Michigan Center for Translational Pathology, University of Michigan ann arbor
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Yale School of Medicine
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Johns Hopkins School of Medicine
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University of Bern
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Karmanos Cancer Center, Wayne State University
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The Sidney Kimmel Cancer Comprehensive Cancer Center at Johns Hopkins
Co-authored papers 3
University of Washington and Fred Hutchinson Cancer Research Center
Co-authored papers 3
OHSU Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Fred Hutchinson Cancer Center, University of Washington
Co-authored papers 3