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Author Details

Paul M Matthews
UK Dementia Research Institute Centre at Imperial College London
1981
459
124
PMIDPaper TitleJournal TitlePublished Year
36384659Inflammatory Diseases, Inflammatory Biomarkers, and Alzheimer Disease: An Observational Analysis and Mendelian Randomization.Neurology2023
37640701Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.Nat Commun2023
37068369The association between brain volume loss and disability in multiple sclerosis: A systematic review.Mult Scler Relat Disord2023
36651180Neurodegenerative disease of the brain: a survey of interdisciplinary approaches.J R Soc Interface2023
36632818Effect of polygenic risk for schizophrenia on cardiac structure and function: a UK Biobank observational study.Lancet Psychiatry2023
36728340Real-world evaluation of ocrelizumab in multiple sclerosis: A systematic review.Ann Clin Transl Neurol2023
34767070Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology.Acta Neuropathol2022
35511193Gene-mapping study of extremes of cerebral small vessel disease reveals TRIM47 as a strong candidate.Brain2022
35726057Identification of early neurodegenerative pathways in progressive multiple sclerosis.Nat Neurosci2022
35524344Human pharmacokinetics of XBD173 and etifoxine distinguish their potential for pharmacodynamic effects mediated by translocator protein.Br J Clin Pharmacol2022
36340756New lesion segmentation for multiple sclerosis brain images with imaging and lesion-aware augmentation.Front Neurosci2022
36269859Metabolome-wide association study on <i>ABCA7</i> indicates a role of ceramide metabolism in Alzheimer's disease.Proc Natl Acad Sci U S A2022
36199077Alzheimer's disease-related transcriptional sex differences in myeloid cells.J Neuroinflammation2022
35922433Genome-wide associations of aortic distensibility suggest causality for aortic aneurysms and brain white matter hyperintensities.Nat Commun2022
35880304Telomere Length and Risk of Incident Fracture and Arthroplasty: Findings From UK Biobank.J Bone Miner Res2022
35976998Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease.Sci Transl Med2022
35255491SARS-CoV-2 is associated with changes in brain structure in UK Biobank.Nature2022
35013236Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aÿ pathology.Nat Commun2022
35125495Relationship between astrocyte reactivity, using novel <sup>11</sup>C-BU99008 PET, and glucose metabolism, grey matter volume and amyloid load in cognitively impaired individuals.Mol Psychiatry2022
33201538Unbalanced SSFP for super-resolution in MRI.Magn Reson Med2021
33495596Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect.Nat Genet2021
34758867Boosting the diagnostic power of amyloid-β PET using a data-driven spatially informed classifier for decision support.Alzheimers Res Ther2021
34079129Gating and modulation of a hetero-octameric AMPA glutamate receptor.Nature2021
34271020Biology of AMPA receptor interacting proteins - From biogenesis to synaptic plasticity.Neuropharmacology2021
34210797Tryptophan-metabolizing gut microbes regulate adult neurogenesis via the aryl hydrocarbon receptor.Proc Natl Acad Sci U S A2021
34267329Astrocyte reactivity with late-onset cognitive impairment assessed in vivo using <sup>11</sup>C-BU99008 PET and its relationship with amyloid load.Mol Psychiatry2021
34145928Activated microglia do not increase 18â¿¿kDa translocator protein (TSPO) expression in the multiple sclerosis brain.Glia2021
34309761Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases.Acta Neuropathol2021
33369822Relationships between retinal layer thickness and brain volumes in the UK Biobank cohort.Eur J Neurol2021
32457287The UK Biobank imaging enhancement of 100,000 participants:â¿¿rationale, data collection, management and future directions.Nat Commun2020
32051456Large-scale Quality Control of Cardiac Imaging in Population Studies: Application to UK Biobank.Sci Rep2020
33203906Accelerated MRI-predicted brain ageing and its associations with cardiometabolic and brain disorders.Sci Rep2020
32817390Sleep, major depressive disorder, and Alzheimer disease: A Mendelian randomization study.Neurology2020
32672370Exploiting relationships between outcomes in Bayesian multivariate network meta-analysis with an application to relapsing-remitting multiple sclerosis.Stat Med2020
32643852Nonlinear biomarker interactions in conversion from mild cognitive impairment to Alzheimer's disease.Hum Brain Mapp2020
32814899Genetic and functional insights into the fractal structure of the heart.Nature2020
32839619A population-based phenome-wide association study of cardiac and aortic structure and function.Nat Med2020
32358523A novel neurodegenerative spectrum disorder in patients with MLKL deficiency.Cell Death Dis2020
32408345Neurofilaments: neurobiological foundations for biomarker applications.Brain2020
32324706E-health and multiple sclerosis.Curr Opin Neurol2020
29369795Cardiovascular magnetic resonance characterization of myocardial and vascular function in rheumatoid arthritis patients.Hellenic J Cardiol2019
31641014Evaluation of multiple sclerosis disability outcome measures using pooled clinical trial data.Neurology2019
31825506Associations of Regional Brain Structural Differences With Aging, Modifiable Risk Factors for Dementia, and Cognitive Performance.JAMA Netw Open2019
31358974New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders.Nat Hum Behav2019
31578541A quantitative neuropathological assessment of translocator protein expression in multiple sclerosis.Brain2019
31484787In vivo detection of cerebral tau pathology in long-term survivors of traumatic brain injury.Sci Transl Med2019
31420598Chronic inflammation in multiple sclerosis - seeing what was always there.Nat Rev Neurol2019
30866968Automated quality control in image segmentation: application to the UK Biobank cardiovascular magnetic resonance imaging study.J Cardiovasc Magn Reson2019
31086805Breaking the cycle: Reversal of flux in the tricarboxylic acid cycle by dimethyl fumarate.Neurol Neuroimmunol Neuroinflamm2019
30403623Learning-Based Quality Control for Cardiac MR Images.IEEE Trans Med Imaging2019
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Guy's Hospital
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School of Public Health, Imperial College London
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Imperial College London
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Imperial College London
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Medicines Research Centre
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Biomedicine and Clinical Research, University Hospital Basel, University of Basel
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Yale School of Medicine, Yale School of Public Health
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University of Oxford
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Cambridge University
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Illumina Inc. 5200 Illumina Way
Co-authored papers 4
McGill University
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Institute for Genomic Medicine, Columbia University Irving Medical Center
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Western University
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Department of Pharmacy, Liyang People's Hospital
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