Author details

Full Name

Daniel R Crooks

Affiliation

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37331486	PRDM10 RCC: A Birt-Hogg-DubÃ©-like Syndrome Associated With Lipoma and Highly Penetrant, Aggressive Renal Tumors Morphologically Resembling Type 2 Papillary Renal Cell Carcinoma.	Urology	2023
37561409	Cryptic splice mutation in the fumarate hydratase gene in patients with clinical manifestations of Hereditary Leiomyomatosis and Renal Cell Cancer.	Hum Mol Genet	2023
37095531	High-throughput and targeted drug screens identify pharmacological candidates against MiT-translocation renal cell carcinoma.	J Exp Clin Cancer Res	2023
36713582	Targeting mutant p53-R248W reactivates WT p53 function and alters the onco-metabolic profile.	Front Oncol	2023
36040304	Resolving Enantiomers of 2-Hydroxy Acids by Nuclear Magnetic Resonance.	Analytical Chemistry	2022
33402335	Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer.	Sci Signal	2021
33805301	NMR Methods for Determining Lipid Turnover via Stable Isotope Resolved Metabolomics.	Metabolites	2021
34108512	Real-Time insight into in vivo redox status utilizing hyperpolarized [1-<sup>13</sup>C] N-acetyl cysteine.	Sci Rep	2021
33165095	Multifocal Renal Cell Carcinomas With Somatic IDH2 Mutation: Report of a Previously Undescribed Neoplasm.	Am J Surg Pathol	2021
32774853	Fumarate hydratase-deficient renal cell carcinoma cells respond to asparagine by activation of the unfolded protein response and stimulation of the hexosamine biosynthetic pathway.		2020
32820045	Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite.	Journal of Biological Chemistry	2020
30725447	Metabolic Labeling of Cultured Mammalian Cells for Stable Isotope-Resolved Metabolomics: Practical Aspects of Tissue Culture and Sample Extraction.	Methods in Molecular Biology	2019
30358041	Photoinducible Oncometabolite Detection.	ChemBioChem	2019
30765854	Targeting Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor 2 (HER2) Expressing Bladder Cancer Using Combination Photoimmunotherapy (PIT).	Sci Rep	2019
31088840	The Metabolic Basis of Kidney Cancer.	Cancer Discovery	2019
29523684	Acute loss of iron-sulfur clusters results in metabolic reprogramming and generation of lipid droplets in mammalian cells.	Journal of Biological Chemistry	2018
29934340	Induction of Thioredoxin-Interacting Protein by a Histone Deacetylase Inhibitor, Entinostat, Is Associated with DNA Damage and Apoptosis in Esophageal Adenocarcinoma.	Mol Cancer Ther	2018
30374112	The Warburg effect in hominis: isotope-resolved metabolism in ccRCC.	Nature Reviews Urology	2018
27960310	Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.	J Am Chem Soc	2016
26719882	SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery.	J Natl Cancer Inst	2016
27070709	SnapShot: Renal Cell Carcinoma.	Cancer Cell	2016
28007899	Use of antisense oligonucleotides to correct the splicing error in ISCU myopathy patient cell lines.	Hum Mol Genet	2016
27728802	Targeting HIF2Î± in Clear-Cell Renal Cell Carcinoma.	Cancer Cell	2016
23943793	Elevated FGF21 secretion, PGC-1Î± and ketogenic enzyme expression are hallmarks of iron-sulfur cluster depletion in human skeletal muscle.	Hum Mol Genet	2014
25490448	Targeting ABL1-mediated oxidative stress adaptation in fumarate hydratase-deficient cancer.	Cancer Cell	2014
23395173	Deletion of iron regulatory protein 1 causes polycythemia and pulmonary hypertension in mice through translational derepression of HIF2Î±.		2013
23280773	Golgi phosphoprotein 4 (GPP130) is a sensitive and selective cellular target of manganese exposure.	Synapse	2013
22101253	Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis.		2012
23035118	Tissue specificity of a human mitochondrial disease: differentiation-enhanced mis-splicing of the Fe-S scaffold gene ISCU renders patient cells more sensitive to oxidative stress in ISCU myopathy.	Journal of Biological Chemistry	2012
22003390	Iron insufficiency compromises motor neurons and their mitochondrial function in Irp2-null mice.	PLoS ONE	2011
19965627	Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery.	Blood	2010
20808827	Expression of human frataxin is regulated by transcription factors SRF and TFAP2.	PLoS ONE	2010
19898775	Role of hepcidin in murine brain iron metabolism.	Cellular and Molecular Life Sciences	2010
20472835	Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.	Blood	2010
17320182	Low-level manganese exposure alters glutamate metabolism in GABAergic AF5 cells.	NeuroToxicology	2007
17469137	Manganese targets m-aconitase and activates iron regulatory protein 2 in AF5 GABAergic cells.	Journal of Neuroscience Research	2007
16408195	GABAergic lineage differentiation of AF5 neural progenitor cells in vitro.	Cell Tissue Res	2006