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Author Details

Stephen E Spurgeon
Knight Cancer Institute, Oregon Health and Science University
2006
66
26
PMIDPaper TitleJournal TitlePublished Year
35263204A phase II study of obinutuzumab in combination with ibrutinib for treatment of relapsed mantle cell lymphoma.Leuk Lymphoma2023
37287113A retrospective single-center analysis of CD-19 directed CAR T-cell therapy in relapsed/refractory mantle cell lymphoma.Leuk Lymphoma2023
36965007Older patients with primary central nervous system lymphoma: Survival and prognostication across 20 U.S. cancer centers.Am J Hematol2023
36960939EBV-positive PCNSL in older patients: incidence, characteristics, tumor pathology, and outcomes across a large multicenter cohort.Leuk Lymphoma2023
36516082Diminished humoral and cellular responses to SARS-CoV-2 vaccines in patients with chronic lymphocytic leukemia.Blood Adv2023
36631449Pevonedistat, a Nedd8-activating enzyme inhibitor, in combination with ibrutinib in patients with relapsed/refractory B-cell non-Hodgkin lymphoma.Blood Cancer J2023
34196037Proapoptotic and immunomodulatory effects of SYK inhibitor entospletinib in combination with obinutuzumab in patients with chronic lymphocytic leukaemia.Br J Clin Pharmacol2022
35657079Ibrutinib plus Bendamustine and Rituximab in Untreated Mantle-Cell Lymphoma.N Engl J Med2022
35868306Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.Cancer Cell2022
36093297Combined epigenetic and immunotherapy for blastic and classical mantle cell lymphoma.Oncotarget2022
35127183Immunogenicity of Pfizer mRNA COVID-19 Vaccination Followed by J&J Adenovirus COVID-19 Vaccination in Two Patients with Chronic Lymphocytic Leukemia.Case Rep Hematol2022
34872103Cellular and humoral immune response to mRNA COVID-19 vaccination in subjects with chronic lymphocytic leukemia.Blood Adv2022
35200084Phase 1/2 study of acalabrutinib and the PI3K delta inhibitor ACP-319 in relapsed/refractory B-cell Non-Hodgkin lymphoma.Leuk Lymphoma2022
34570876Single-route CNS prophylaxis for aggressive non-Hodgkin lymphomas: real-world outcomes from 21 US academic institutions.Blood2022
33210562Natural history of noninfectious, ibrutinib-attributable adverse events in patients with chronic lymphocytic leukemia.Leuk Lymphoma2021
33683501A phase Ib, open label, dose escalation trial of the anti-CD37 monoclonal antibody, BI 836826, in combination with ibrutinib in patients with relapsed/refractory chronic lymphocytic leukemia.Invest New Drugs2021
33504141Entospletinib and obinutuzumab in patients with relapsed/refractory chronic lymphocytic leukemia and B-cell malignancies.Haematologica2021
34518841Immunogenicity of Pfizer mRNA COVID-19 vaccination followed by J&J adenovirus COVID-19 vaccination in two CLL patients.medRxiv2021
33089525A novel somatic PLCG2 variant associated with resistance to BTK and SYK inhibition in chronic lymphocytic leukemia.Eur J Haematol2021
33328591Phase 1b study of tirabrutinib in combination with idelalisib or entospletinib in previously treated B-cell lymphoma.Leukemia2021
32278675The First Report of Endoscopic Ultrasound-guided Intralesional Rituximab in a Patient With Mantle Cell Lymphoma Presenting With Isolated Colorectal Involvement.Clin Lymphoma Myeloma Leuk2020
31177537Phase 1-2 study of vorinostat (SAHA), cladribine and rituximab (SCR) in relapsed B-cell non-Hodgkin lymphoma and previously untreated mantle cell lymphoma.Br J Haematol2019
29249186Obinutuzumab monotherapy in previously untreated chronic lymphocytic leukemia.Leuk Lymphoma2018
30214788Exaggerated arthropod assault: Eosinophilic dermatosis in a patient with small lymphocytic lymphoma.Clin Case Rep2018
29872489Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples.Oncotarget2018
30333627Functional genomic landscape of acute myeloid leukaemia.Nature2018
29797667Comorbidities predict inferior outcomes in chronic lymphocytic leukemia treated with ibrutinib.Cancer2018
27391978Ibrutinib is an effective treatment for B-cell prolymphocytic leukaemia.Br J Haematol2017
28487504Obinutuzumab is Effective in Chronic Lymphocytic Leukemia and Rheumatoid Arthritis After Rituximab Failure: A Case Report.Am J Case Rep2017
28385778Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myeloma.Haematologica2017
28181280Identification of targeted therapies for rare adult mature T-cell leukemia using functional ex vivo screening of primary patient samples.Am J Hematol2017
28838991SYK inhibition thwarts the BAFF - B-cell receptor crosstalk and thereby antagonizes Mcl-1 in chronic lymphocytic leukemia.Haematologica2017
28013106CPX-351 exhibits potent and direct ex vivo cytotoxicity against AML blasts with enhanced efficacy for cells harboring the FLT3-ITD mutation.Leuk Res2017
27761930Concurrent STAT3, DNMT3A, and TET2 mutations in T-LGL leukemia with molecularly distinct clonal hematopoiesis of indeterminate potential.Am J Hematol2017
26968534Phase 2 study of idelalisib and entospletinib: pneumonitis limits combination therapy in relapsed refractory CLL and NHL.Blood2016
27582059Targeting BCL-2 and ABL/LYN in Philadelphia chromosome-positive acute lymphoblastic leukemia.Sci Transl Med2016
28040733Recommendations for Clinical Trial Development in Mantle Cell Lymphoma.J Natl Cancer Inst2016
26935129Cardiac non-Hodgkin's lymphoma: clinical characteristics and trends in survival.Eur J Haematol2016
26764355Postibrutinib outcomes in patients with mantle cell lymphoma.Blood2016
25146490Otlertuzumab (TRU-016), an anti-CD37 monospecific ADAPTIR(â¿¢) therapeutic protein, for relapsed or refractory NHL patients.Br J Haematol2015
26425337Ibrutinib in mantle cell lymphoma patients: glass half full? Evidence and opinion.Ther Adv Hematol2015
26606677Cyclin-Dependent Kinase Inhibitor P1446A Induces Apoptosis in a JNK/p38 MAPK-Dependent Manner in Chronic Lymphocytic Leukemia B-Cells.PLoS One2015
26254279Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma.Oncotarget2015
26231802MYD88 mutation analysis of a rare composite chronic lymphocyte leukemia and lymphoplasmacytic lymphoma by flow cytometry cell sorting.Ann Hematol2015
26059948Long-term follow-up of MCL patients treated with single-agent ibrutinib: updated safety and efficacy results.Blood2015
24381226A phase 1 study evaluating the safety and tolerability of otlertuzumab, an anti-CD37 mono-specific ADAPTIR therapeutic protein in chronic lymphocytic leukemia.Blood2014
25628989Acute promyelocytic leukemia with JAK2 V617F and severe differentiation syndrome.Leuk Res Rep2014
25441688Chronic lymphocytic leukemia with a FGFR3 translocation: case report and literature review of an uncommon cytogenetic event.Cancer Genet2014
25125625Aberrations of MYC are a common event in B-cell prolymphocytic leukemia.Am J Clin Pathol2014
24615778A phase 1 study of the PI3Kδ inhibitor idelalisib in patients with relapsed/refractory mantle cell lymphoma (MCL).Blood2014
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Collaborators

City of Hope National Medical Center
Co-authored papers 17
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 12
Oregon Health & Science University
Co-authored papers 10
Oregon Health & Science University School of Medicine
Co-authored papers 10
Oregon Health and Science University
Co-authored papers 6
Oregon Health & Science University
Co-authored papers 5
St Jude Children's Research Hospital.
Co-authored papers 5
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 5
Oregon Health & Science University
Co-authored papers 4
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 4
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 4
Oregon Health and Science University
Co-authored papers 4
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 4
Oregon Health & Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Oregon Health & Science University
Co-authored papers 3
Oregon Health & Science University
Co-authored papers 3
Oregon Health & Science University, University of California Berkeley
Co-authored papers 3
University of Utah Huntsman Cancer Institute
Co-authored papers 3
The Ohio State University
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Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 3
Oregon Health and Science University
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
University of Miami, Sylvester Comprehensive Cancer Center
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 2