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Author Details

Geoffrey I McFadden
The University of Melbourne
1987
206
63
PMIDPaper TitleJournal TitlePublished Year
36709382A candidate transporter allowing symbiotic dinoflagellates to feed their coral hosts.ISME Commun2023
37053271Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics.PLoS Biol2023
37474653mRNA vaccine against malaria tailored for liver-resident memory T cells.Nat Immunol2023
34285364Cell surface carbohydrates of symbiotic dinoflagellates and their role in the establishment of cnidarian-dinoflagellate symbiosis.ISME J2022
356564786⿳-Modifed α-GalCer-peptide conjugate vaccine candidates protect against liver-stage malaria.RSC Chem Biol2022
36530422Targeting malaria parasites with novel derivatives of azithromycin.Front Cell Infect Microbiol2022
36070203Roles of the apicoplast across the life cycles of rodent and human malaria parasites.J Eukaryot Microbiol2022
34448326Cell wall proteomic analysis of the cnidarian photosymbionts Breviolum minutum and Cladocopium goreaui.J Eukaryot Microbiol2022
34452759Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity.Bioorg Chem2021
35492393<i>Plasmodium berghei</i> Hsp90 contains a natural immunogenic I-A<sup>b</sup>-restricted antigen common to rodent and human <i>Plasmodium</i> species.Curr Res Immunol2021
33741975Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites.Nat Commun2021
33713652Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes.Int J Parasitol2021
33486759Development of Plasmodium-specific liver-resident memory CD8<sup>+</sup> T cells after heat-killed sporozoite immunization in mice.Eur J Immunol2021
34491587The cell wall polysaccharides of a photosynthetic relative of apicomplexans, Chromera velia.J Phycol2021
32396839A Natural Peptide Antigen within the Plasmodium Ribosomal Protein RPL6 Confers Liver T<sub>RM</sub> Cell-Mediated Immunity against Malaria in Mice.Cell Host Microbe2020
31914409Characterization of the apicoplast-localized enzyme <i>Tg</i>UroD in <i>Toxoplasma gondii</i> reveals a key role of the apicoplast in heme biosynthesis.J Biol Chem2020
32993629Retargeting azithromycin analogues to have dual-modality antimalarial activity.BMC Biol2020
32678064A single point mutation in the <i>Plasmodium falciparum</i> FtsH1 metalloprotease confers actinonin resistance.Elife2020
32591409Glycolipid-peptide vaccination induces liver-resident memory CD8<sup>+</sup> T cells that protect against rodent malaria.Sci Immunol2020
32187549Division and Adaptation to Host Environment of Apicomplexan Parasites Depend on Apicoplast Lipid Metabolic Plasticity and Host Organelle Remodeling.Cell Rep2020
30442527Plasmodium: More Don'ts.Trends Parasitol2019
31993121Symbiotic lifestyle triggers drastic changes in the gene expression of the algal endosymbiont <i>Breviolum minutum</i> (Symbiodiniaceae).Ecol Evol2019
31370870Alternative splicing is required for stage differentiation in malaria parasites.Genome Biol2019
31365939Anti-plasmodial Effects of Zanthoxylum zanthoxyloides.Planta Med2019
31393007A new marine prasinophyte genus alternates between a flagellate and a dominant benthic stage with microrhizoids for adhesion.J Phycol2019
31303446Bed Nets, Insecticides, and Antimalarials: Where to Next?Trends Parasitol2019
31618655Liver-Resident Memory CD8<sup>+</sup> T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.Immunity2019
30782661Alternative Splicing in Apicomplexan Parasites.mBio2019
28902970A genetic screen in rodent malaria parasites identifies five new apicoplast putative membrane transporters, one of which is essential in human malaria parasites.Cell Microbiol2018
29987724Isolating the Plasmodium falciparum Apicoplast Using Magnetic Beads.Methods Mol Biol2018
30482182Genome of tiny predator with big appetite.BMC Biol2018
30282039CD8<sup>+</sup> T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver.Cell Rep2018
29476099Sequential Membrane Rupture and Vesiculation during Plasmodium berghei Gametocyte Egress from the Red Blood Cell.Sci Rep2018
29483266Host biotin is required for liver stage development in malaria parasites.Proc Natl Acad Sci U S A2018
27324409Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast.Cell Microbiol2017
29109165Validation of Putative Apicoplast-Targeting Drugs Using a Chemical Supplementation Assay in Cultured Human Malaria Parasites.Antimicrob Agents Chemother2017
29084838Development of a Novel CD4<sup>+</sup> TCR Transgenic Line That Reveals a Dominant Role for CD8<sup>+</sup> Dendritic Cells and CD40 Signaling in the Generation of Helper and CTL Responses to Blood-Stage Malaria.J Immunol2017
28708996Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.Cell2017
28828570The cryptomonad nucleomorph.Protoplasma2017
28803903Structured illumination microscopy reveals actin I localization in discreet foci in Plasmodium berghei gametocytes.Exp Parasitol2017
28617870A novel genetic technique in Plasmodium berghei allows liver stage analysis of genes required for mosquito stage development and demonstrates that de novo heme synthesis is essential for liver stage development in the malaria parasite.PLoS Pathog2017
28586662Evolution: Of X-Cells and X-Men.Curr Biol2017
28923023Comparative transcriptomics of female and male gametocytes in Plasmodium berghei and the evolution of sex in alveolates.BMC Genomics2017
27789127Is the Mitochondrion a Good Malaria Drug Target?Trends Parasitol2017
27773518The apicoplast: now you see it, now you don't.Int J Parasitol2017
27081071Parasites resistant to the antimalarial atovaquone fail to transmit by mosquitoes.Science2016
26347246The Plasmodium translocon of exported proteins component EXP2 is critical for establishing a patent malaria infection in mice.Cell Microbiol2016
27793563Targeting Protein Translation in Organelles of the Apicomplexa.Trends Parasitol2016
27692609Liver-Resident Memory CD8<sup>+</sup> T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.Immunity2016
27855676Erratum to: Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite.Malar J2016
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Collaborators

Stuart A Ralph
Bio21 Molecular Science and Biotechnology Institute, University of Melbourne
Co-authored papers 22
David S Roos
University of Pennsylvania
Co-authored papers 8
James G Beeson
Burnet Institute
Co-authored papers 6
Martin Fraunholz
Julius-Maximilians-Universitat Wurzburg
Co-authored papers 4
Akhil B Vaidya
Center for Molecular Parasitology, Drexel University College of Medicine
Co-authored papers 3
Ross L Coppel
Nursing and Health SciencesMonash UniversityClaytonVictoriaAustralia.
Co-authored papers 2
Arnab Pain
King Abdullah University of Science and Technology
Co-authored papers 2
Stephen L Hoffman
Inc., 9800 Medical Center Drive
Co-authored papers 2
Stefan A Rensing
University of Marburg
Co-authored papers 2
Nicholas Collins
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 2
Neil Hall
Earlham Institute
Co-authored papers 2
Michael W Mather
Center for Molecular Parasitology, Drexel University College of Medicine
Co-authored papers 2
Anthony W Purcell
Monash Biomedicine Discovery Institute, Monash University
Co-authored papers 2
Inga Siden-Kiamos
Institute of Molecular Biology and Biotechnology
Co-authored papers 2
Ian T Paulsen
Macquarie University
Co-authored papers 1
Alister G Craig
Malawi-Liverpool-Wellcome Trust Clinical Research Program
Co-authored papers 1
Bernard Suh
Center for Biomolecular Science and Engineering, University of California
Co-authored papers 1
Matthew Berriman
Wellcome Sanger Institute
Co-authored papers 1
Keith D James
Wellcome Trust Sanger Institute
Co-authored papers 1
Kim Rutherford
University of Cambridge
Co-authored papers 1
Scott R Burrows
Co-authored papers 1
Man-Suen Chan
University of Oxford
Co-authored papers 1
Julia F Hopkins
Foundation Medicine Inc.
Co-authored papers 1
Leda M Cummings
Institute for Genome Research
Co-authored papers 1
Robert Eveleigh
Victor Philip Dahdaleh Institute of Genomic Medicine at McGill University
Co-authored papers 1
Jeremy D Selengut
Craig Venter Institute, 9704 Medical Center Drive
Co-authored papers 1
David M A Martin
University of Dundee
Co-authored papers 1
Samuel V Angiuoli
Personal Genome Diagnostics Inc.
Co-authored papers 1
Jeremy Peterson
The Institute for Genomic Research, 9712 Medical Center Drive
Co-authored papers 1
Claire M Fraser
Institute for Genome Sciences, University of Maryland School of Medicine
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Release 1.2