Author details

Full Name

Jennifer A Akiyama

Affiliation

ORCID

Career Start Year

1996

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37425940	Combinatorial transcription factor binding encodes cis-regulatory wiring of forebrain GABAergic neurogenesis.	bioRxiv	2023
37081156	Topologically associating domain boundaries are required for normal genome function.	Commun Biol	2023
37425964	Cell Type- and Tissue-specific Enhancers in Craniofacial Development.	bioRxiv	2023
34913122	Characterization of Mammalian In Vivo Enhancers Using Mouse Transgenesis and CRISPR Genome Editing.	Methods Mol Biol	2022
33398137	Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.	Nature	2021
33782603	Ultraconserved enhancer function does not require perfect sequence conservation.	Nat Genet	2021
34256850	Coding and noncoding variants in EBF3 are involved in HADDS and simplex autism.	Hum Genomics	2021
32737473	Supervised enhancer prediction with epigenetic pattern recognition and targeted validation.	Nat Methods	2020
32169219	Comprehensive InÂ Vivo Interrogation Reveals Phenotypic Impact of Human Enhancer Variants.	Cell	2020
33037424	Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.	Nature	2020
29420474	Enhancer redundancy provides phenotypic robustness in mammalian development.	Nature	2018
30503521	Parkinson-Associated SNCA Enhancer Variants Revealed by Open Chromatin in Mouse Dopamine Neurons.	Am J Hum Genet	2018
29358049	Ultraconserved Enhancers Are Required for Normal Development.	Cell	2018
28827824	Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb.	PLoS Comput Biol	2017
28538179	HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development.	Cell Reports	2017
27768887	Progressive Loss of Function in a Limb Enhancer during Snake Evolution.	Cell	2016
27287804	A distal 594â¿¿bp ECR specifies Hmx1 expression in pinna and lateral facial morphogenesis and is regulated by the Hox-Pbx-Meis complex.	Development	2016
27703156	Genome-wide compendium and functional assessment of in vivo heart enhancers.	Nat Commun	2016
27693352	Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease.	Cell	2016
26628093	Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma.	Development	2015
24658141	Function-based identification of mammalian enhancers using site-specific integration.	Nat Methods	2014
25249388	Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease.	Nat Commun	2014
25188404	Tissue-specific RNA expression marks distant-acting developmental enhancers.	PLoS Genet	2014
24752179	Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.	Genome Res	2014
23375746	A high-resolution enhancer atlas of the developing telencephalon.	Cell	2013
24360275	Rapid and pervasive changes in genome-wide enhancer usage during mammalian development.	Cell	2013
24159046	Fine tuning of craniofacial morphology by distant-acting enhancers.	Science	2013
24127591	Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants.	Proc Natl Acad Sci U S A	2013
22138689	Large-scale discovery of enhancers from human heart tissue.	Nat Genet	2011
20729851	ChIP-Seq identification of weakly conserved heart enhancers.	Nat Genet	2010
19212405	ChIP-seq accurately predicts tissue-specific activity of enhancers.	Nature	2009
19268701	Functional autonomy of distant-acting human enhancers.	Genomics	2009
18176564	Ultraconservation identifies a small subset of extremely constrained developmental enhancers.	Nat Genet	2008
18772437	Human-specific gain of function in a developmental enhancer.	Science	2008
17936576	In vivo characterization of human APOA5 haplotypes.	Genomics	2007
17086198	In vivo enhancer analysis of human conserved non-coding sequences.	Nature	2006
15117734	Analysis of apolipoprotein A5, c3, and plasma triglyceride concentrations in genetically engineered mice.	Arterioscler Thromb Vasc Biol	2004
11867335	Surfactant protein-A--deficient mice display an exaggerated early inflammatory response to a beta-resistant strain of influenza A virus.	Am J Respir Cell Mol Biol	2002
12376353	Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema.	Am J Physiol Lung Cell Mol Physiol	2002
12070278	Tissue distribution of surfactant proteins A and D in the mouse.	J Histochem Cytochem	2002
11350793	GM-CSF mediates alveolar macrophage proliferation and type II cell hypertrophy in SP-D gene-targeted mice.	Am J Physiol Lung Cell Mol Physiol	2001
10423401	Characterization of the mouse collectin gene locus.	Am J Respir Cell Mol Biol	1999
10226076	Ultrastructure of phospholipid mixtures reconstituted with surfactant proteins B and D.	Am J Respir Cell Mol Biol	1999
9751757	Altered surfactant homeostasis and alveolar type II cell morphology in mice lacking surfactant protein D.	Proc Natl Acad Sci U S A	1998
8725251	Localization and developmental expression of surfactant proteins D and A in the respiratory tract of the mouse.	Pediatric Research	1996