Skip to Main Content

Author Details

Debanu Das
Accelero Biostructures Inc., USA XPose Therapeutics Inc.
2001
49
18
PMIDPaper TitleJournal TitlePublished Year
38068959A New Drug Discovery Platform: Application to DNA Polymerase Eta and Apurinic/Apyrimidinic Endonuclease 1.Int J Mol Sci2023
33115610Fragment- and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response.Prog Biophys Mol Biol2021
34900730Early Drug Discovery and Development of Novel Cancer Therapeutics Targeting DNA Polymerase Eta (POLH).Front Oncol2021
27050129UHM-ULM interactions in the RBM39-U2AF65 splicing-factor complex.Acta Crystallogr D Struct Biol2016
26940875PNT1 Is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast.J Biol Chem2016
26940874Crystal Structure and Activity Studies of the C11 Cysteine Peptidase from Parabacteroides merdae in the Human Gut Microbiome.J Biol Chem2016
25825768Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.Proc Natl Acad Sci U S A2015
26416531Structure of Liver Receptor Homolog-1 (NR5A2) with PIP3 hormone bound in the ligand binding pocket.J Struct Biol2015
24174223Crystal structure of a putative quorum sensing-regulated protein (PA3611) from the Pseudomonas-specific DUF4146 family.Proteins2014
25288771The signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1.Proc Natl Acad Sci U S A2014
25044324Crystal structures of three representatives of a new Pfam family PF14869 (DUF4488) suggest they function in sugar binding/uptake.Protein Sci2014
24888348Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome.Protein Sci2014
24646163Structure and computational analysis of a novel protein with metallopeptidase-like and circularly permuted winged-helix-turn-helix domains reveals a possible role in modified polysaccharide biosynthesis.BMC Bioinformatics2014
23572527Structure and function of the DUF2233 domain in bacteria and in the human mannose 6-phosphate uncovering enzyme.J Biol Chem2013
24123814Structure and function of a novel LD-carboxypeptidase a involved in peptidoglycan recycling.J Bacteriol2013
24004689Two Pfam protein families characterized by a crystal structure of protein lpg2210 from Legionella pneumophila.BMC Bioinformatics2013
22505259Application of DEN refinement and automated model building to a difficult case of molecular-replacement phasing: the structure of a putative succinyl-diaminopimelate desuccinylase from Corynebacterium glutamicum.Acta Crystallogr D Biol Crystallogr2012
21445265Structure and function of the first full-length murein peptide ligase (Mpl) cell wall recycling protein.PLoS One2011
21532589Improved molecular replacement by density- and energy-guided protein structure optimization.Nature2011
19913036Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.J Mol Biol2010
20836087The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.Protein Sci2010
20944232Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944230Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944228The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944225Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944224Structure of Bacteroides thetaiotaomicron BT2081 at 2.05⿿ÿ resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944223A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2⿿ÿ resolution.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944222Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944221The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944219The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944218Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944217Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944214Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944211The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45⿿ÿ resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944209Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944208The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20122942Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.J Mol Biol2010
19000695A structural basis for the regulatory inactivation of DnaA.J Mol Biol2009
19567872Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.J Biol Chem2009
19173316Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.Proteins2009
19127588Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution.Proteins2009
17275331Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids.J Struct Biol2007
17764033Structure-based inference of molecular functions of proteins of unknown function from Berkeley Structural Genomics Center.J Struct Funct Genomics2007
17348019Crystal structure of a novel single-stranded DNA binding protein from Mycoplasma pneumoniae.Proteins2007
15562512Crystal structure of the conserved hypothetical protein MPN330 (GI: 1674200) from Mycoplasma pneumoniae.Proteins2005
16211501Structural genomics of minimal organisms and protein fold space.J Struct Funct Genomics2005
15130474The crystal structure of the monomeric reverse transcriptase from Moloney murine leukemia virus.Structure2004
15326591Structural and energetic characterization of nucleic acid-binding to the fingers domain of Moloney murine leukemia virus reverse transcriptase.Proteins2004
11567084A directed approach to improving the solubility of Moloney murine leukemia virus reverse transcriptase.Protein Sci2001
  • 1 - 49 of 49

Recommended Authors

Ashwani Kumar
Bhabha Atomic Research Centre
Career Start Year 2009
Number of shared co-authors 0
Eunju Kwon
Yeungnam University
Career Start Year 2007
Number of shared co-authors 0
Lester G Carter
Stanford University
Career Start Year 2004
Number of shared co-authors 2
Ruiying Wu
Argonne National Laboratory
Career Start Year 2003
Number of shared co-authors 5
Elena Evdokimova
University of Toronto
Career Start Year 2002
Number of shared co-authors 3
P??l Stenmark
Stockholm University
Career Start Year 2001
Number of shared co-authors 0
B Martin Hallberg
Karolinska Institutet
Career Start Year 2000
Number of shared co-authors 5
Jeffrey B Bonanno
Albert Einstein College of Medicine
Career Start Year 1999
Number of shared co-authors 6
Stephen A McMahon
University of St Andrews
Career Start Year 1998
Number of shared co-authors 0
Alexei Savchenko
University of Toronto
Career Start Year 1997
Number of shared co-authors 8
Li-Wei Hung
Los Alamos National Laboratory
Career Start Year 1997
Number of shared co-authors 9
J Michael Sauder
Eli Lilly and Co.
Career Start Year 1996
Number of shared co-authors 6
Orly Dym
Weizmann Institute of Science
Career Start Year 1995
Number of shared co-authors 6
Zihe Rao
Nankai University
Career Start Year 1995
Number of shared co-authors 6
Min Zhou
College of Materials Science and Engineering, Hunan University
Career Start Year 1994
Number of shared co-authors 5
Stephen Matthews
Imperial College London
Career Start Year 1993
Number of shared co-authors 1
Youngchang Kim
Argonne National Laboratory
Career Start Year 1993
Number of shared co-authors 10
Diana R Tomchick
University of Texas Southwestern Medical Center
Career Start Year 1993
Number of shared co-authors 1
P??r Nordlund
Karolinska Institutet, BioClinicum J6
Career Start Year 1989
Number of shared co-authors 7
Chang-Yub Kim
Los Alamos National Laboratory
Career Start Year 1989
Number of shared co-authors 5
Liang Tong
Columbia University
Career Start Year 1988
Number of shared co-authors 9
Steven C Almo
Albert Einstein College of Medicine
Career Start Year 1988
Number of shared co-authors 10
Natalie C J Strynadka
The University of British Columbia
Career Start Year 1988
Number of shared co-authors 3
Donald D Lorimer
Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Career Start Year 1986
Number of shared co-authors 0
Thomas B Acton
Center for Advanced Biotechnology and Medicine, The State University of New Jersey
Career Start Year 1986
Number of shared co-authors 10
John F Hunt
Columbia University
Career Start Year 1986
Number of shared co-authors 8
Aled M Edwards
University of Toronto
Career Start Year 1984
Number of shared co-authors 8
Stephen K Burley
The State University of New Jersey
Career Start Year 1982
Number of shared co-authors 16
Andrzej Joachimiak
Center for Structural Biology of Infectious Diseases, University of Chicago
Career Start Year 1979
Number of shared co-authors 16
Tom Alber
University of California berkeley
Career Start Year 1976
Number of shared co-authors 5

Collaborators

Ashley M Deacon
Accelero Biostructures Inc., USA XPose Therapeutics Inc.
Co-authored papers 36
Adam Godzik
University of California Riverside
Co-authored papers 33
Hsiu-Ju Chiu
Joint Center for Structural Genomics
Co-authored papers 32
Marc-Andr?? Elsliger
Joint Center for Structural Genomics
Co-authored papers 31
Scott A Lesley
Merck & Co., Inc.
Co-authored papers 31
Ian A Wilson
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 31
Mitchell D Miller
Rice University
Co-authored papers 29
Heath E Klock
Merck & Co., Inc.
Co-authored papers 27
Mark W Knuth
Joint Center for Structural Genomics
Co-authored papers 27
Lukasz Jaroszewski
University of California Riverside School of Medicine
Co-authored papers 26
Herbert L Axelrod
Joint Center for Structural Genomics
Co-authored papers 25
Joanna C Grant
Joint Center for Structural Genomics
Co-authored papers 24
Qingping Xu
Argonne National Laboratory
Co-authored papers 24
Abhinav Kumar
University of Lucknow
Co-authored papers 24
Marc C Deller
Incyte Corporation
Co-authored papers 23
Julie Feuerhelm
Co-authored papers 23
Thomas Clayton
Celgene/Bristol-Myers Squibb Corporation
Co-authored papers 23
Sanjay Krishna
Institute of Science, Banaras Hindu University
Co-authored papers 22
Ron Reyes
Co-authored papers 22
Kevin K Jin
Cardiovascular Institute, Stanford University School of Medicine
Co-authored papers 22
Lian Duan
Brown University
Co-authored papers 22
Andrew T Morse
Co-authored papers 22
Gye Won Han
Bridge Institute, University of Southern California
Co-authored papers 22
Dennis Carlton
Co-authored papers 22
Christine B Trame
Joint Center for Structural Genomics ( http:/www.jcsg.org )
Co-authored papers 22
Henry van den Bedem
University of California San Francisco
Co-authored papers 22
Dana Weekes
Joint Center for Structural Genomics, Sanford-Burnham Medical Research Institute
Co-authored papers 22
Edward Nigoghossian
Genomics Institute of the Novartis Research Foundation
Co-authored papers 22
Polat Abdubek
Regeneron Pharmaceuticals, Inc.
Co-authored papers 22
Linda Okach
Co-authored papers 22
Release 1.2