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Author Details

Torsten Wittmann
University of California san francisco
1997
59
33
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36715499Growth cone advance requires EB1 as revealed by genomic replacement with a light-sensitive variant.Elife2023
35266954The E3 ligase TRIM1 ubiquitinates LRRK2 and controls its localization, degradation, and toxicity.J Cell Biol2022
35476350Controlling Cell Shape and Microtubule Organization by Extracellular Matrix Micropatterning.Methods Mol Biol2022
35090591Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules.Curr Biol2022
33237838pHLARE: a new biosensor reveals decreased lysosome pH in cancer cells.Mol Biol Cell2021
32371345Lights, cytoskeleton, action: Optogenetic control of cell dynamics.Curr Opin Cell Biol2020
31879907Optogenetic Control of Microtubule Dynamics.Methods Mol Biol2020
30992364Tau repeat regions contain conserved histidine residues that modulate microtubule-binding in response to changes in pH.J Biol Chem2019
30730055Microtubule Plus End Dynamics - Do We Know How Microtubules Grow?: Cells boost microtubule growth by promoting distinct structural transitions at growing microtubule ends.Bioessays2019
29379139Local control of intracellular microtubule dynamics by EB1 photodissociation.Nat Cell Biol2018
28646105The glycolytic enzyme phosphofructokinase-1 assembles into filaments.J Cell Biol2017
28232523GSK3-mediated CLASP2 phosphorylation modulates kinetochore dynamics.J Cell Sci2017
26903539NBR1 enables autophagy-dependent focal adhesion turnover.J Cell Biol2016
27672021Autophagy in adhesion and migration.J Cell Sci2016
27238282Doublecortin Is Excluded from Growing Microtubule Ends and Recognizes the GDP-Microtubule Lattice.Curr Biol2016
26212133Enzymatically Generated CRISPR Libraries for Genome Labeling and Screening.Dev Cell2015
26702830Migration of Founder Epithelial Cells Drives Proper Molar Tooth Positioning and Morphogenesis.Dev Cell2015
24030547LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex.Hum Mol Genet2014
25231989Acetylcholine receptor (AChR) clustering is regulated both by glycogen synthase kinase 3β (GSK3β)-dependent phosphorylation and the level of CLIP-associated protein 2 (CLASP2) mediating the capture of microtubule plus-ends.J Biol Chem2014
24974047Quantitative imaging in cell biology. Preface.Methods Cell Biol2014
24974036Analysis of focal adhesion turnover: a quantitative live-cell imaging example.Methods Cell Biol2014
24974023Fluorescence live cell imaging.Methods Cell Biol2014
24974019Concepts in quantitative fluorescence microscopy.Methods Cell Biol2014
24832456Host cell polarity proteins participate in innate immunity to Pseudomonas aeruginosa infection.Cell Host Microbe2014
24821701Expression of an expanded CGG-repeat RNA in a single pair of primary sensory neurons impairs olfactory adaptation in Caenorhabditis elegans.Hum Mol Genet2014
24923837Neuronal deletion of GSK3β increases microtubule speed in the growth cone and enhances axon regeneration via CRMP-2 and independently of MAP1B and CLASP2.BMC Biol2014
24859005CLASPs link focal-adhesion-associated microtubule capture to localized exocytosis and adhesion site turnover.Nat Cell Biol2014
23107073Host microtubule plus-end binding protein CLASP1 influences sequential steps in the Trypanosoma cruzi infection process.Cell Microbiol2013
22264541Imaging intracellular protein dynamics by spinning disk confocal microscopy.Methods Enzymol2012
23267416Microtubule dynamics regulation contributes to endothelial morphogenesis.Bioarchitecture2012
22748381+TIPs: SxIPping along microtubule ends.Trends Cell Biol2012
22908306Targeting and transport: how microtubules control focal adhesion dynamics.J Cell Biol2012
22483942EB1-recruited microtubule +TIP complexes coordinate protrusion dynamics during 3D epithelial remodeling.Curr Biol2012
22467876Multisite phosphorylation disrupts arginine-glutamate salt bridge networks required for binding of cytoplasmic linker-associated protein 2 (CLASP2) to end-binding protein 1 (EB1).J Biol Chem2012
21909260Chlamydia trachomatis co-opts GBF1 and CERT to acquire host sphingomyelin for distinct roles during intracellular development.PLoS Pathog2011
22031288Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression.Mol Biol Cell2011
20719263Analysis of microtubule polymerization dynamics in live cells.Methods Cell Biol2010
20729842Analysis of microtubule dynamic instability using a plus-end growth marker.Nat Methods2010
19289791GSK3beta phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment.J Cell Biol2009
19167337SnapShot: Microtubule Regulators I.Cell2009
19203588SnapShot: Microtubule regulators II.Cell2009
19103811EBs clip CLIPs to growing microtubule ends.J Cell Biol2008
17981134Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks.Dev Cell2007
16525027Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.Mol Biol Cell2006
15723782Microtubule cytoskeleton: a new twist at the end.Curr Biol2005
15955847Spatial regulation of CLASP affinity for microtubules by Rac1 and GSK3beta in migrating epithelial cells.J Cell Biol2005
14645234Regulation of microtubule destabilizing activity of Op18/stathmin downstream of Rac1.J Biol Chem2004
15530396Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked.Curr Biol2004
15385625Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts.Mol Biol Cell2004
12543069A high-speed multispectral spinning-disk confocal microscope system for fluorescent speckle microscopy of living cells.Methods2003
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Collaborators

Jeffrey van Haren
University of California San Francisco
Co-authored papers 10
Diane L Barber
University of California San Francisco
Co-authored papers 4
Anthony A Hyman
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 3
Joanne N Engel
University of California san francisco
Co-authored papers 2
Niels Galjart
Co-authored papers 2
Matthew P Jacobson
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Jayanta Debnath
University of California San Francisco
Co-authored papers 2
Jennifer Haynes
Joan C. Edwards School of Medicine, Marshall University
Co-authored papers 1
William T Dauer
Peter O'Donnell Jr. Brain Institute
Co-authored papers 1
Scott A Oakes
Pritzker School of Medicine, University of Chicago
Co-authored papers 1
Timothy C Cox
University of Missouri-Kansas City Kansas City
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Robert J Nichols
Stanford University
Co-authored papers 1
Christian Mirescu
Merck & Co. Inc.
Co-authored papers 1
Molly FitzGibbon
University of California San Diego
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Annie Hiniker
University of California, San Diego and VA San Diego Healthcare System (D.G.
Co-authored papers 1
Cherilyn A Elwell
University of California san francisco
Co-authored papers 1
Erik Verschueren
University of California San Francisco
Co-authored papers 1
Elizabeth M Earley
University of California San Francisco
Co-authored papers 1
Carson Balen
University of California San Diego
Co-authored papers 1
Jordan Ye
University of California San Francisco
Co-authored papers 1
Justin M Kollman
University of Washington
Co-authored papers 1
John L R Rubenstein
UCSF Medical School
Co-authored papers 1
Ciro Iaccarino
University of Sassari
Co-authored papers 1
Jyoti Srivastava
Moffitt Cancer Center
Co-authored papers 1
John Von Dollen
University of California San Francisco
Co-authored papers 1
Emily J Davis
University of California San Francisco
Co-authored papers 1
Hannah Ahrendt
University of California San Diego
Co-authored papers 1
Rainer Pepperkok
Translational Lung Research Center Heidelberg, German Center for Lung Research
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