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Author Details
Full Name
David E Levy
Affiliation
NYU Grossman School of Medicine
ORCID
Career Start Year
1979
Papers
194
H Index
96
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37526084
Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity.
J Clin Invest
2023
35799901
Assessing the Presence of Hematopoietic Stem and Progenitor Cells in Mouse Spleen.
Bio Protoc
2022
34124936
The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4<sup>+</sup> T Cells via a Novel CDK8-GATA3-FOXP3 Pathway.
Mol Cell Biol
2021
33605027
Mitochondrial STAT3 regulates antioxidant gene expression through complex I-derived NAD in triple negative breast cancer.
Mol Oncol
2021
34378531
Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome.
Elife
2021
34507993
IL-6 enhances CD4 cell motility by sustaining mitochondrial Ca<sup>2+</sup> through the noncanonical STAT3 pathway.
Proc Natl Acad Sci U S A
2021
33305182
STAT3 Inhibitor OPB-51602 Is Cytotoxic to Tumor Cells Through Inhibition of Complex I and ROS Induction.
iScience
2020
30463877
HDAC stimulates gene expression through BRD4 availability in response to IFN and in interferonopathies.
J Exp Med
2018
28584133
Mitochondrial dysfunction induced by a SH2 domain-targeting STAT3 inhibitor leads to metabolic synthetic lethality in cancer cells.
Proc Natl Acad Sci U S A
2017
28356390
The kinase TBK1 functions in dendritic cells to regulate T cell homeostasis, autoimmunity, and antitumor immunity.
J Exp Med
2017
26904939
Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation.
Cell Rep
2016
27127173
Cytoplasmic, full length and novel cleaved variant, TBLR1 reduces apoptosis in prostate cancer under androgen deprivation.
Oncotarget
2016
26939124
PKR Transduces MDA5-Dependent Signals for Type I IFN Induction.
PLoS Pathog
2016
26198641
STAT3 regulated ARF expression suppresses prostate cancer metastasis.
Nat Commun
2015
26499136
Erratum: STAT3 regulated ARF expression suppresses prostate cancer metastasis.
Nat Commun
2015
26283727
A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.
Mol Cell Biol
2015
25150294
STAT3 supports experimental K-RasG12D-induced murine myeloproliferative neoplasms dependent on serine phosphorylation.
Blood
2014
22785228
STAT1-regulated lung MDSC-like cells produce IL-10 and efferocytose apoptotic neutrophils with relevance in resolution of bacterial pneumonia.
Mucosal Immunol
2013
24312439
The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation.
PLoS One
2013
23878400
The human RVB complex is required for efficient transcription of type I interferon-stimulated genes.
Mol Cell Biol
2013
22159083
Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.
Am J Physiol Cell Physiol
2012
24058748
Comparative evolutionary genomics of the STAT family of transcription factors.
JAKSTAT
2012
22520849
STATus report on tetramers.
Immunity
2012
22679098
Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interface.
Science
2012
22312003
Inhibition of pyrimidine synthesis reverses viral virulence factor-mediated block of mRNA nuclear export.
J Cell Biol
2012
22252317
Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.
Mol Cell Biol
2012
22264274
STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas.
Breast Cancer Res
2012
22365663
Constitutive type I interferon modulates homeostatic balance through tonic signaling.
Immunity
2012
21215659
The transcription factor STAT3 is required for T helper 2 cell development.
Immunity
2011
22323926
Induction and function of type I and III interferon in response to viral infection.
Curr Opin Virol
2011
21810606
STAT3 negatively regulates type I IFN-mediated antiviral response.
J Immunol
2011
21586612
STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.
Cancer Res
2011
21730287
Inhibition of nonsense-mediated RNA decay by the tumor microenvironment promotes tumorigenesis.
Mol Cell Biol
2011
21730023
TLR4 engagement during TLR3-induced proinflammatory signaling in dendritic cells promotes IL-10-mediated suppression of antitumor immunity.
Cancer Res
2011
21339641
Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α-producing and partially matured phenotype.
J Clin Invest
2011
21505191
STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis.
Blood
2011
21219575
Distinct inflammatory signals have physiologically divergent effects on epigenetic regulation of Foxp3 expression and Treg function.
Am J Transplant
2011
20436908
Functional crosstalk between type I and II interferon through the regulated expression of STAT1.
PLoS Biol
2010
21084727
A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.
Aging (Albany NY)
2010
20829794
A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells.
Nature
2010
20643331
NF-kappaB-ISGF3 transcription factor cooperation: coincidence detector or memory chip?
Immunity
2010
19234181
IL-21 mediates suppressive effects via its induction of IL-10.
J Immunol
2009
19956438
Activation of Stat3 in renal tumors.
Am J Transl Res
2009
20064451
Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors.
Immunity
2009
19690134
Identification of a Stat3-dependent transcription regulatory network involved in metastatic progression.
Cancer Res
2009
19608706
Reduction of Stat3 activity attenuates HIV-induced kidney injury.
J Am Soc Nephrol
2009
19604309
Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells.
Immunology
2009
19357722
Knockdown of Stat3 activity in vivo prevents diabetic glomerulopathy.
Kidney Int
2009
19414776
c-Maf regulates IL-10 expression during Th17 polarization.
J Immunol
2009
19556508
Mitochondrial STAT3 supports Ras-dependent oncogenic transformation.
Science
2009
1 - 50 of 194
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The University of Melbourne
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Center for Cancer Research, National Cancer Institute, National Institutes of Health
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Luiz F L Reis
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Icahn School of Medicine at Mount Sinai
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