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Author Details

Sadhna Phanse
University of Regina
2008
64
25
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36755019Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT.Nat Commun2023
37985878Co-fractionation-mass spectrometry to characterize native mitochondrial protein assemblies in mammalian neurons and brain.Nat Protoc2023
37501930HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2.Front Physiol2023
37060561Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload.Cell Rep2023
37454293Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload.Cell Rep2023
37471224Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions.Cell Rep2023
34492227Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes.Structure2022
35616533Development of a Method Combining Peptidiscs and Proteomics to Identify, Stabilize, and Purify a Detergent-Sensitive Membrane Protein Assembly.J Proteome Res2022
35835781Auxotrophic and prototrophic conditional genetic networks reveal the rewiring of transcription factors in Escherichia coli.Nat Commun2022
35831314Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.Nat Commun2022
35848500<i>In vitro</i> toxicity screening of amorphous silica nanoparticles using mitochondrial fraction exposure followed by MS-based proteomic analysis.Analyst2022
36126381Insights into SACS pathological attributes in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS)â¿¿.Curr Opin Chem Biol2022
36004308A computational approach to rapidly design peptides that detect SARS-CoV-2 surface protein S.NAR Genom Bioinform2022
33417854Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.Mol Cell2021
33521598From fuzziness to precision medicine: on the rapidly evolving proteomics with implications in mitochondrial connectivity to rare human disease.iScience2021
33895137ZapG (YhcB/DUF1043), a novel cell division protein in gamma-proteobacteria linking the Z-ring to septal peptidoglycan synthesis.J Biol Chem2021
34582199Human-Soybean Allergies: Elucidation of the Seed Proteome and Comprehensive Protein-Protein Interaction Prediction.J Proteome Res2021
34244791The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF.Nucleic Acids Res2021
33958595Author Correction: Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex.Nat Commun2021
33436616Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex.Nat Commun2021
31504172A Gaussian process-based definition reveals new and bona fide genetic interactions compared to a multiplicative model in the Gram-negative Escherichia coli.Bioinformatics2020
31986926Misconnecting the dots: altered mitochondrial protein-protein interactions and their role in neurodegenerative disorders.Expert Rev Proteomics2020
33033576Mitochondria under the spotlight: On the implications of mitochondrial dysfunction and its connectivity to neuropsychiatric disorders.Comput Struct Biotechnol J2020
33259812Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2.Mol Cell2020
32853540BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.Cell Syst2020
32596240Exploring the Impact of <i>PARK2</i> Mutations on the Total and Mitochondrial Proteome of Human Skin Fibroblasts.Front Cell Dev Biol2020
32325033BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.Cell Syst2020
31536960Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.iScience2019
31844052Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action.Nat Commun2019
31754640ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores.Commun Biol2019
31308550EPIC: software toolkit for elution profile-based inference of protein complexes.Nat Methods2019
29176613Global landscape of cell envelope protein complexes in Escherichia coli.Nat Biotechnol2018
30126533Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.Cell Chem Biol2018
29659649Systems analysis of the genetic interaction network of yeast molecular chaperones.Mol Omics2018
28903051Features of the Chaperone Cellular Network Revealed through Systematic Interaction Mapping.Cell Rep2017
29128334A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.Cell Syst2017
28786313Insights from protein-protein interaction studies on bacterial pathogenesis.Expert Rev Proteomics2017
26921299Novel Interactome of Saccharomyces cerevisiae Myosin Type II Identified by a Modified Integrated Membrane Yeast Two-Hybrid (iMYTH) Screen.G3 (Bethesda)2016
27732863Systematic Genetic Screens Reveal the Dynamic Global Functional Organization of the Bacterial Translation Machinery.Cell Rep2016
26774489Conditional Epistatic Interaction Maps Reveal Global Functional Rewiring of Genome Integrity Pathways in Escherichia coli.Cell Rep2016
25367773Mitochondrial targets for pharmacological intervention in human disease.J Proteome Res2015
26344197Panorama of ancient metazoan macromolecular complexes.Nature2015
26870755Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes.Data Brief2015
26949739Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.Cell Syst2015
26121405Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.Nat Methods2015
25963654Spindle Checkpoint Factors Bub1 and Bub2 Promote DNA Double-Strand Break Repair by Nonhomologous End Joining.Mol Cell Biol2015
25782749Extracting high confidence protein interactions from affinity purification data: at the crossroads.J Proteomics2015
25546499Yeast mitochondrial protein-protein interactions reveal diverse complexes and disease-relevant functional relationships.J Proteome Res2015
25316676Novel function discovery with GeneMANIA: a new integrated resource for gene function prediction in Escherichia coli.Bioinformatics2015
24373767NleH defines a new family of bacterial effector kinases.Structure2014
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Collaborators

Mohan Babu
University of Regina
Co-authored papers 44
Andrew Emili
Boston University School of Medicine, Boston University
Co-authored papers 29
Alla Gagarinova
University of Regina
Co-authored papers 17
James Vlasblom
University of Regina
Co-authored papers 15
Hiroyuki Aoki
University of Regina
Co-authored papers 15
Jack F Greenblatt
College Street, University of Toronto
Co-authored papers 14
Ashkan Golshani
Ottawa Institute of Systems Biology, Carleton University
Co-authored papers 13
Zoran Minic
University of Ottawa
Co-authored papers 12
Ramy H Malty
University of Toronto, University of Regina
Co-authored papers 11
Matthew Jessulat
University of Regina
Co-authored papers 11
John Parkinson
The Hospital for Sick Children
Co-authored papers 9
Walid A Houry
University of Toronto
Co-authored papers 9
Ashwani Kumar
Bhabha Atomic Research Centre
Co-authored papers 9
Bahram Samanfar
Agriculture and Agri-Food Canada
Co-authored papers 8
Viktor Deineko
University of Northern British Columbia
Co-authored papers 8
Qingzhou Zhang
Sprott Center for Stem Cell Research, Ottawa Hospital Research Institute
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Shoshana J Wodak
VIB-VUB Center for Structural Biology
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Gary D Bader
University of Toronto
Co-authored papers 6
Mohsen Hooshyar
Department of Biology and Ottawa Institute of Systems Biology, Carleton University
Co-authored papers 6
Xinghua Guo
University of Toronto, College Street
Co-authored papers 6
Hongbo Guo
Beihang University
Co-authored papers 6
Ke Jin
West China Hospital, Sichuan University
Co-authored papers 6
Stefan Wuchty
University of Miami
Co-authored papers 5
Sunyoung Kim
University of Regina
Co-authored papers 5
Oxana Pogoutse
University of Toronto
Co-authored papers 5
Zhaolei Zhang
University of Toronto
Co-authored papers 4
Dima Kozakov
Stony Brook University
Co-authored papers 4
Dzmitry Padhorny
Co-authored papers 4
Daniel Burnside
Ottawa Institute of Systems Biology, University of Ottawa, Carleton University
Co-authored papers 4
Igor Stagljar
University of Toronto, Canada Mediterranean Institute for Life Sciences
Co-authored papers 4
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