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Author Details

Thomas Wilhelm
Institute of Biochemistry and Molecular Immunology, RWTH Aachen University
2000
53
21
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36383121Capitalizing on paradoxical activation of the mitogen-activated protein kinase pathway for treatment of Imatinib-resistant mast cell leukemia.Hematol Oncol2023
36297968Influence of Viscose Fibre Geometry on the Structure-Property Relationships of High-Density Polyethylene Composites.Polymers (Basel)2022
35813499Erythropoietin Enhances Post-ischemic Migration and Phagocytosis and Alleviates the Activation of Inflammasomes in Human Microglial Cells.Front Cell Neurosci2022
36233127Endoplasmic Reticulum Homeostasis Regulates TLR4 Expression and Signaling in Mast Cells.Int J Mol Sci2022
32161259Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy.Nat Commun2020
31837347Differential use of BTK and PLC in FcεRI- and KIT-mediated mast cell activation: A marginal role of BTK upon KIT activation.Biochim Biophys Acta Mol Cell Res2020
30931942The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors.Cell Death Dis2019
31683519EPO and TMBIM3/GRINA Promote the Activation of the Adaptive Arm and Counteract the Terminal Arm of the Unfolded Protein Response after Murine Transient Cerebral Ischemia.Int J Mol Sci2019
31211943EPO regulates neuroprotective Transmembrane BAX Inhibitor-1 Motif-containing (TMBIM) family members GRINA and FAIM2 after cerebral ischemia-reperfusion injury.Exp Neurol2019
29630766Autophagy during ageing - from Dr Jekyll to Mr Hyde.FEBS J2018
28882853Neuronal inhibition of the autophagy nucleation complex extends life span in post-reproductive <i>C. elegans</i>.Genes Dev2017
29423023Infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia.Oncotarget2017
29017148Inhibition of neuronal autophagy mediates longevity.Aging (Albany NY)2017
27091446ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair.J Cell Biol2016
27206658Differential Lyn-dependence of the SHIP1-deficient mast cell phenotype.Cell Commun Signal2016
26891149Epigenetic silencing of AKAP12 in juvenile myelomonocytic leukemia.Epigenetics2016
25300487Super Natural II--a database of natural products.Nucleic Acids Res2015
26265469Bacterial rotary export ATPases are allosterically regulated by the nucleotide second messenger cyclic-di-GMP.J Biol Chem2015
24934728Phenotype prediction based on genome-wide DNA methylation data.BMC Bioinformatics2014
25058668Identification of related peptides through the analysis of fragment ion mass shifts.J Proteome Res2014
23326482Combination of a proteomics approach and reengineering of meso scale network models for prediction of mode-of-action for tyrosine kinase inhibitors.PLoS One2013
24028687Parallel evolution of genome structure and transcriptional landscape in the Epsilonproteobacteria.BMC Genomics2013
23425659The 1,4-benzodiazepine Ro5-4864 (4-chlorodiazepam) suppresses multiple pro-inflammatory mast cell effector functions.Cell Commun Signal2013
23352970Investigation into mechanisms mediating the inhibitory effect of 1,4-benzodiazepines on mast cells by gene expression profiling.Life Sci2013
22182511MEK/Erk-based negative feedback mechanism involved in control of Steel Factor-triggered production of Krüppel-like factor 2 in mast cells.Cell Signal2012
22415796Evaluation of deoxyhypusine synthase inhibitors targeting BCR-ABL positive leukemias.Invest New Drugs2012
20346131The ancient mammalian KRAB zinc finger gene cluster on human chromosome 8q24.3 illustrates principles of C2H2 zinc finger evolution associated with unique expression profiles in human tissues.BMC Genomics2010
20498836Reconstruction and validation of RefRec: a global model for the yeast molecular interaction network.PLoS One2010
20172945DASS-GUI: a user interface for identification and analysis of significant patterns in non-sequential data.Bioinformatics2010
18805906DiProDB: a database for dinucleotide properties.Nucleic Acids Res2009
19605418DiProGB: the dinucleotide properties genome browser.Bioinformatics2009
19737387The smallest chemical reaction system with bistability.BMC Syst Biol2009
18023456Structural robustness of metabolic networks with respect to multiple knockouts.J Theor Biol2008
17188807Boolean networks with biologically relevant rules show ordered behavior.Biosystems2007
17594488Constitutive upregulation of the transforming growth factor-beta pathway in rheumatoid arthritis synovial fibroblasts.Arthritis Res Ther2007
17677498Analysis of structures causing instabilities.Phys Rev E Stat Nonlin Soft Matter Phys2007
17381238Posttranscriptional expression regulation: what determines translation rates?PLoS Comput Biol2007
17393854Protein subcomplexes--molecular machines with highly specialized functions.IEEE Trans Nanobioscience2007
17008552Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL-positive leukemias identified by a proteomics approach.Blood2007
17032678DASS: efficient discovery and p-value calculation of substructures in unordered data.Bioinformatics2007
16819806The new classification scheme of the genetic code, its early evolution, and tRNA usage.J Bioinform Comput Biol2006
16789814Integrated assessment and prediction of transcription factor binding.PLoS Comput Biol2006
15598828Dynamic simulation of protein complex formation on a genomic scale.Bioinformatics2005
15832363Identification and characterization of protein subcomplexes in yeast.Proteomics2005
15888729Common patterns in type II restriction enzyme binding sites.Nucleic Acids Res2005
15326222Post-transcriptional expression regulation in the yeast Saccharomyces cerevisiae on a genomic scale.Mol Cell Proteomics2004
17052121Analysis of structural robustness of metabolic networks.Syst Biol (Stevenage)2004
15693616A new classification scheme of the genetic code.J Mol Evol2004
12772153Analysis of interaction in patterned multienzyme layers by using scanning electrochemical microscopy.Angew Chem Int Ed Engl2003
16247890Physical and functional modularity of the protein network in yeast.Mol Cell Proteomics2003
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Collaborators

Andreas Beyer
University of Cologne
Co-authored papers 11
Jens Hollunder
Flanders Institute for Biotechnology, Ghent University
Co-authored papers 7
Patrick Ziegler
Co-authored papers 2
Christopher T Workman
Technical University of Denmark
Co-authored papers 2
Andreas Schuppert
Joint Research Centre for Computational Biomedicine, University Hospital RWTH Aachen
Co-authored papers 1
Michael Steffens
Federal Institute for Drugs and Medical Devices (BfArM)
Co-authored papers 1
Ulrich M??ller
Clinic for Child and Adolescents Psychiatry, Friedrich Schiller University Jena
Co-authored papers 1
D??rte Radke
Institute for Community Medicine - SHIP/KEF, University Medicine Greifswald
Co-authored papers 1
Charlotte M Niemeyer
Co-authored papers 1
Eytan Ruppin
National Cancer Institute
Co-authored papers 1
Martin Kuiper
Norwegian University of Science and Technology
Co-authored papers 1
Robert Preissner
Institute for Physiology, Charite-University Medicine Berlin
Co-authored papers 1
Kalle Leinonen
Co-authored papers 1
Dana Reichmann
The A. Silberman Institute of Life Sciences, The Hebrew University of Jerusalem
Co-authored papers 1
Trey Ideker (CM4AI)
University of California San Diego
Co-authored papers 1
Christoph Plass
German Cancer Research Center
Co-authored papers 1
Pekka Ruusuvuori
Institute of Biomedicine, University of Turku
Co-authored papers 1
Release 1.2