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Author Details

Jeffrey J Delrow
Clinical Research Division, Fred Hutchinson Cancer Research Center
1992
86
47
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35210305Insufficiency of compound immune checkpoint blockade to overcome engineered T cell exhaustion in pancreatic cancer.J Immunother Cancer2022
34244513Multiplexed functional genomic analysis of 5' untranslated region mutations across the spectrum of prostate cancer.Nat Commun2021
34101353Neural G0: a quiescent-like state found in neuroepithelial-derived cells and glioma.Mol Syst Biol2021
33306674Autocrine insulin pathway signaling regulates actin dynamics in cell wound repair.PLoS Genet2020
30867038Correction to: NSAID use and somatic exomic mutations in Barrett's esophagus.Genome Med2019
31601799N<sup>6</sup>-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis.Nat Commun2019
31591594Expansion of primitive human hematopoietic stem cells by culture in a zwitterionic hydrogel.Nat Med2019
29486792NSAID use and somatic exomic mutations in Barrett's esophagus.Genome Med2018
29897930Loss of Fnip1 alters kidney developmental transcriptional program and synergizes with TSC1 loss to promote mTORC1 activation and renal cyst formation.PLoS One2018
30520725A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV.Elife2018
28586635Tin protoporphyrin activates the oxidant-dependent NRF2-cytoprotective pathway and mitigates acute kidney injury.Transl Res2017
28364472Transcriptional Signatures of Sleep Duration Discordance in Monozygotic Twins.Sleep2017
28119225The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma.Leuk Res2017
28465358Mutant IDH1 regulates the tumor-associated immune system in gliomas.Genes Dev2017
28596487ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5.Oncotarget2017
26753621Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations.Mol Cancer Res2016
27521269Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis.Immunity2016
25582857Heme exporter FLVCR is required for T cell development and peripheral survival.J Immunol2015
26673326Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells.Cell Rep2015
25754639Wash interacts with lamin and affects global nuclear organization.Curr Biol2015
25798938Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.Nat Biotechnol2015
25581430Germline ETV6 mutations in familial thrombocytopenia and hematologic malignancy.Nat Genet2015
24131213Functionally and phenotypically distinct subpopulations of marrow stromal cells are fibroblast in origin and induce different fates in peripheral blood monocytes.Stem Cells Dev2014
25291178Autonomous stimulation of cancer cell plasticity by the human NKG2D lymphocyte receptor coexpressed with its ligands on cancer cells.PLoS One2014
23154965Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells.Cancer Discov2013
23815575Differential regulatory T cell activity in HIV type 1-exposed seronegative individuals.AIDS Res Hum Retroviruses2013
23651857Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.Genes Dev2013
22267581Rescued tolerant CD8 T cells are preprogrammed to reestablish the tolerant state.Science2012
23177352UpSET recruits HDAC complexes and restricts chromatin accessibility and acetylation at promoter regions.Cell2012
23049838Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system.PLoS One2012
22473991Fbw7 and p53 cooperatively suppress advanced and chromosomally unstable intestinal cancer.Mol Cell Biol2012
20842525Gene expression array testing of FFPE archival breast tumor samples: an optimized protocol for WG-DASL sample preparation.Breast Cancer Res Treat2011
21791427Innate signals overcome acquired TCR signaling pathway regulation and govern the fate of human CD161(hi) CD8α⁺ semi-invariant T cells.Blood2011
21343912Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression.EMBO J2011
20178373Calf-thymus topoisomerase I equilibrates metastable secondary structure subsequent to relaxation of superhelical stress.Biochemistry2010
20805356Chromatin remodeling around nucleosome-free regions leads to repression of noncoding RNA transcription.Mol Cell Biol2010
19103660Quality assessment and data analysis for microRNA expression arrays.Nucleic Acids Res2009
18451802Zbtb4 represses transcription of P21CIP1 and controls the cellular response to p53 activation.EMBO J2008
18832352The temporal program of chromosome replication: genomewide replication in clb5{Delta} Saccharomyces cerevisiae.Genetics2008
18632612Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients.Cancer Res2008
18245482Repression of B-cell linker (BLNK) and B-cell adaptor for phosphoinositide 3-kinase (BCAP) is important for lymphocyte transformation by rel proteins.Cancer Res2008
18241851Drosophila growth and development in the absence of dMyc and dMnt.Dev Biol2008
17016442Interferon regulatory factor-1 regulates reconstituted extracellular matrix (rECM)-mediated apoptosis in human mammary epithelial cells.Oncogene2007
19383305Use of high density antibody arrays to validate and discover cancer serum biomarkers.Mol Oncol2007
17898168A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.Proc Natl Acad Sci U S A2007
18075583Chromatin remodelling at promoters suppresses antisense transcription.Nature2007
17636020Replication in hydroxyurea: it's a matter of time.Mol Cell Biol2007
17693258Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses.Cell2007
16652139Genomic instability during Myc-induced lymphomagenesis in the bursa of Fabricius.Oncogene2006
17623909Analysis of gene expression, copy number and palindrome formation with a Dt40 enriched cDNA microarray.Subcell Biochem2006
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Collaborators

Oncode Institute, Netherlands Cancer Institute
Co-authored papers 6
Clinical Research Division, Fred Hutchinson Cancer Center
Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
Co-authored papers 3
University of Washington School of Medicine
Co-authored papers 3
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Beijing Hospital of Traditional Chinese Medicine, Capital Medical University
Co-authored papers 3
Arizona State University
Co-authored papers 3
Lerner Research Institute, Cleveland Clinic
Co-authored papers 3
Co-authored papers 2
Fred Hutchinson Cancer Center
Co-authored papers 2
Co-authored papers 2
Samsung Medical Center, Sungkyunkwan University School
Co-authored papers 2
University of Dundee
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of Washington, USA Brotman Baty Institute for Precision Medicine
Co-authored papers 2
University of Washington
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Center for Computational Biomedicine, Harvard Medical School
Co-authored papers 1
Center for Computational Neuroscience, Flatiron Institute
Co-authored papers 1
The Roslin Institute & R(D)SVS, University of Edinburgh
Co-authored papers 1
Graduate School of Medicine, The University of Tokyo
Co-authored papers 1
University of Washington
Co-authored papers 1
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Brandeis University
Co-authored papers 1
University of Michigan ann arbor
Co-authored papers 1