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Author Details

Ira Mellman
Genentech Inc.
1974
300
117
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38095631Nucleotide modifications enable rational design of TLR7-selective ligands by blocking RNase cleavage.J Exp Med2024
36599350CD8<sup>+</sup> T cell-intrinsic IL-6 signaling promotes resistance to anti-PD-L1 immunotherapy.Cell Rep Med2023
37543621Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors.Nat Commun2023
37820582The cancer-immunity cycle: Indication, genotype, and immunotype.Immunity2023
37258670In situ tumour arrays reveal early environmental control of cancer immunity.Nature2023
37165196Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer.Nature2023
35263013Allelic variation in HLA-DRB1 is associated with development of antidrug antibodies in cancer patients treated with atezolizumab that are neutralizing in vitro.Clin Transl Sci2022
35379739TIGIT-CD226-PVR axis: advancing immune checkpoint blockade for cancer immunotherapy.J Immunother Cancer2022
35471657Coming of Age: Human Genomics and the Cancer-Immune Set Point.Cancer Immunol Res2022
35446649ESCRT-mediated membrane repair protects tumor-derived cells against T cell attack.Science2022
35446348Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation.J Cell Biol2022
36099881NKG2A and HLA-E define an alternative immune checkpoint axis in bladder cancer.Cancer Cell2022
35314846Loss of the intracellular enzyme QPCTL limits chemokine function and reshapes myeloid infiltration to augment tumor immunity.Nat Immunol2022
35332327IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines.Nat Immunol2022
35263569Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8<sup>+</sup> T cell responses.Immunity2022
33175106Gut microbiome stability and dynamics in healthy donors and patients with non-gastrointestinal cancers.J Exp Med2021
33602823Activation of NF-κB and p300/CBP potentiates cancer chemoimmunotherapy through induction of MHC-I antigen presentation.Proc Natl Acad Sci U S A2021
33827905Intratumoral CD103+ CD8+ T cells predict response to PD-L1 blockade.J Immunother Cancer2021
33903764Gremlin 1<sup>+</sup> fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues.Nat Immunol2021
34732896Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues.Nature2021
34767762Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification.Cancer Cell2021
34172722Molecular determinants of response to PD-L1 blockade across tumor types.Nat Commun2021
31260672E-Cadherin is Dispensable to Maintain Langerhans Cells in the Epidermis.J Invest Dermatol2020
35122038PD-L1 expression by dendritic cells is a key regulator of T-cell immunity in cancer.Nat Cancer2020
32103181Peripheral T cell expansion predicts tumour infiltration and clinical response.Nature2020
31940002Mutation position is an important determinant for predicting cancer neoantigens.J Exp Med2020
33232321Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation.PLoS One2020
32923115Dexamethasone premedication suppresses vaccine-induced immune responses against cancer.Oncoimmunology2020
32430334Polygenic risk for skin autoimmunity impacts immune checkpoint blockade in bladder cancer.Proc Natl Acad Sci U S A2020
30784580The Dendritic Cell Strikes Back.Immunity2019
31745090Transposable element expression in tumors is associated with immune infiltration and increased antigenicity.Nat Commun2019
31064777Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8<sup>+</sup> T Cells in Murine Syngeneic Tumor Models.Cancer Immunol Res2019
29229751SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer.J Cell Biol2018
30463956Germline genetic polymorphisms influence tumor gene expression and immune cell infiltration.Proc Natl Acad Sci U S A2018
30297397Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).Proc Natl Acad Sci U S A2018
30566889The Dendritic Cell Strikes Back.Immunity2018
30282040The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function.Cell Rep2018
29443960TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.Nature2018
28591131Visualization of early influenza A virus trafficking in human dendritic cells using STED microscopy.PLoS One2017
28280247T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.Science2017
28220772Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice.Nat Commun2017
28130292Transcriptional determinants of tolerogenic and immunogenic states during dendritic cell maturation.J Cell Biol2017
28102259Elements of cancer immunity and the cancer-immune set point.Nature2017
26944201MAP Kinase Inhibition Promotes T Cell and Anti-tumor Activity in Combination with PD-L1 Checkpoint Blockade.Immunity2016
27932575Natural killer cell granules converge to avoid collateral damage.J Cell Biol2016
27599456High cell-surface density of HER2 deforms cell membranes.Nat Commun2016
27622041Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop.Oncoimmunology2016
27330810Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule.J Immunother Cancer2016
26963549Voices of biotech.Nat Biotechnol2016
27036972De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute.Cancer Immunol Res2016
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Collaborators

Shannon J Turley
Co-authored papers 16
Suchit Jhunjhunwala
Genentech Inc.
Co-authored papers 6
Matthew L Albert
Co-authored papers 5
Lloyd J Old
Ludwig Institute for Cancer Research
Co-authored papers 5
Kai Simons
Germany Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 4
Hiroshi Ohno
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Lillian B Cohn
Co-authored papers 3
Bryan Lo
The Ottawa Hospital/University of Ottawa
Co-authored papers 3
Yasin Senbabaoglu
Co-authored papers 3
Tushar Bhangale
Genentech Inc.
Co-authored papers 2
Terrance G Johns
Telethon Kids Institute
Co-authored papers 2
Miriam Merad
The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Peter M Haverty
Co-authored papers 2
Julie Hunkapiller
Genentech Inc.
Co-authored papers 2
Sacha Gnjatic
The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Lloyd G Cantley
Yale University School of Medicine
Co-authored papers 2
Steven A Rosenberg
University of Colorado School of Medicine
Co-authored papers 1
Tobias C Walther
Harvard T. H. Chan School of Public Health
Co-authored papers 1
Yao-Tseng Chen
From Population Health Services (Chen)
Co-authored papers 1
Cathie Martin
John Innes Centre
Co-authored papers 1
Jackie Y Ying
Institute of Materials Research and Engineering
Co-authored papers 1
Tian Zhang
Wuhan University of Technology, PR China Shaoxing Institute for Advanced Research
Co-authored papers 1
Allyson L Byrd
Genentech Inc.
Co-authored papers 1
Maria-Elena Torres-Padilla
Institute of Epigenetics and Stem Cells (IES)
Co-authored papers 1
John M Greally
Co-authored papers 1
Leena Tripathi
International Institute of Tropical Agriculture
Co-authored papers 1
Gustavo Stolovitzky
IBM T.J. Watson Research Center
Co-authored papers 1
Benjamin D Greenbaum
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Tuuli Lappalainen
Columbia University
Co-authored papers 1
Carolyn R Bertozzi
Stanford University
Co-authored papers 1
Release 1.2