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Author Details

Brook E Heaton
Duke University School of Medicine
2012
14
10
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37578235A low-background, fluorescent assay to evaluate inhibitors of diverse viral proteases.J Virol2023
36282911Host protein kinases required for SARS-CoV-2 nucleocapsid phosphorylation and viral replication.Sci Signal2022
35862698A Virion-Based Combination Vaccine Protects against Influenza and SARS-CoV-2 Disease in Mice.J Virol2022
35985334Rapid tissue prototyping with micro-organospheres.Stem Cell Reports2022
34043740TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2.PLoS Pathog2021
33658342Engineered influenza virions reveal the contributions of non-hemagglutinin structural proteins to vaccine mediated protection.J Virol2021
32843534Development of a Fluorescence-Based, High-Throughput SARS-CoV-2 3CL<sup>pro</sup> Reporter Assay.J Virol2020
33128895Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.Cell Stem Cell2020
31358986DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection.Nat Microbiol2019
30174294Mycobacterial Mutagenesis and Drug Resistance Are Controlled by Phosphorylation- and Cardiolipin-Mediated Inhibition of the RecA Coprotease.Mol Cell2018
28588131Rationally Designed Influenza Virus Vaccines That Are Antigenically Stable during Growth in Eggs.mBio2017
28813663A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor.Cell Rep2017
24842925Deficiency of double-strand DNA break repair does not impair Mycobacterium tuberculosis virulence in multiple animal models of infection.Infect Immun2014
22334680Molecular structure and function of the novel BrnT/BrnA toxin-antitoxin system of Brucella abortus.J Biol Chem2012
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Collaborators

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Princess Maxima Center for Pediatric Oncology
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Gladstone Institutes
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Icahn School of Medicine at Mount Sinai
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Meyer Cancer Center
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Sloan Kettering Institute
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Memorial Sloan Kettering Cancer Center
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Hanover Medical School
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The Ohio State University College of Medicine
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Sloan Kettering Institute
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NYU Grossman School of Medicine
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Regeneron Pharmaceuticals, Inc.
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