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Author Details

Anjana Rao
La Jolla Institute for Immunology
1983
321
120
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36626549OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis.Proc Natl Acad Sci U S A2023
37669386TET3-mediated DNA oxidation is essential for intestinal epithelial cell response to stressors.Proc Natl Acad Sci U S A2023
37115668PSGL-1 attenuates early TCR signaling to suppress CD8<sup>+</sup> T cell progenitor differentiation and elicit terminal CD8<sup>+</sup> T cell exhaustion.Cell Rep2023
37406303Inducible disruption of <i>Tet</i> genes results in myeloid malignancy, readthrough transcription, and a heterochromatin-to-euchromatin switch.Proc Natl Acad Sci U S A2023
34937926TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures.Nat Immunol2022
35450882HMCES protects immunoglobulin genes specifically from deletions during somatic hypermutation.Genes Dev2022
36266342Acute deletion of TET enzymes results in aneuploidy in mouse embryonic stem cells through decreased expression of Khdc3.Nat Commun2022
331729745-Azacytidine Transiently Restores Dysregulated Erythroid Differentiation Gene Expression in TET2-Deficient Erythroleukemia Cells.Mol Cancer Res2021
35014296DNA Translocation through Vertically Stacked 2D Layers of Graphene and Hexagonal Boron Nitride Heterostructure Nanopore.ACS Appl Bio Mater2021
349190535-Hydroxymethylcytosine-mediated active demethylation is required for mammalian neuronal differentiation and function.Elife2021
34697491Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety.Nat Nanotechnol2021
34678516Novel Antibodies for the Simple and Efficient Enrichment of Native O-GlcNAc Modified Peptides.Mol Cell Proteomics2021
34158086Roles of TET and TDG in DNA demethylation in proliferating and non-proliferating immune cells.Genome Biol2021
34288360Whole-genome analysis of TET dioxygenase function in regulatory T cells.EMBO Rep2021
34282330BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells.Nat Immunol2021
32253314Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells.Proc Natl Acad Sci U S A2020
34321714Effect of single nanoparticle-nanopore interaction strength on ionic current modulation.Sens Actuators B Chem2020
34109316An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.Nat Cancer2020
31965999TET methylcytosine oxidases: new insights from a decade of research.J Biosci2020
33173218Scientific divagations: from signaling and transcription to chromatin changes in T cells.Nat Immunol2020
32730592TET family dioxygenases and the TET activator vitamin C in immune responses and cancer.Blood2020
32504054DNMT3A and TET2 mutations reshape hematopoiesis in opposing ways.Nat Genet2020
32142687HMCES Functions in the Alternative End-Joining Pathway of the DNA DSB Repair during Class Switch Recombination in B Cells.Mol Cell2020
32493815Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength.J Immunol2020
31028100TET enzymes augment activation-induced deaminase (AID) expression via 5-hydroxymethylcytosine modifications at the <i>Aicda</i> superenhancer.Sci Immunol2019
31868585MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions.Elife2019
31467060Dysregulation of the TET family of epigenetic regulators in lymphoid and myeloid malignancies.Blood2019
31436949Unusual Activity of a <i>Chlamydomonas</i> TET/JBP Family Enzyme.Biochemistry2019
31235913Structural basis of HMCES interactions with abasic DNA and multivalent substrate recognition.Nat Struct Mol Biol2019
31316684DNA Translocation through Hybrid Bilayer Nanopores.J Phys Chem C Nanomater Interfaces2019
31371502Paradoxical association of TET loss of function with genome-wide DNA hypomethylation.Proc Natl Acad Sci U S A2019
31019078Targeting the NFAT:AP-1 transcriptional complex on DNA with a small-molecule inhibitor.Proc Natl Acad Sci U S A2019
30814732NR4A transcription factors limit CAR T cell function in solid tumours.Nature2019
31043609Loss of TET2 and TET3 in regulatory T cells unleashes effector function.Nat Commun2019
30809228TET Enzymes and 5hmC in Adaptive and Innate Immune Systems.Front Immunol2019
31152140TOX and TOX2 transcription factors cooperate with NR4A transcription factors to impose CD8<sup>+</sup> T cell exhaustion.Proc Natl Acad Sci U S A2019
30449622Impact of Genetic Polymorphisms on Human Immune Cell Gene Expression.Cell2018
29887596YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity.Oncogene2018
29991556Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal.Blood2018
29985393TCR signal strength controls thymic differentiation of iNKT cell subsets.Nat Commun2018
27869820TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells.Nat Immunol2017
28408905TET Methylcytosine Oxidases in T Cell and B Cell Development and Function.Front Immunol2017
28450733TET family dioxygenases and DNA demethylation in stem cells and cancers.Exp Mol Med2017
28373404Precancer Atlas to Drive Precision Prevention Trials.Cancer Res2017
28283662Exhaustion-associated regulatory regions in CD8<sup>+</sup> tumor-infiltrating T cells.Proc Natl Acad Sci U S A2017
28970470NFAT2 is a critical regulator of the anergic phenotype in chronic lymphocytic leukaemia.Nat Commun2017
28813683TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.Cell Rep2017
28504700Lineage-specific functions of TET1 in the postimplantation mouse embryo.Nat Genet2017
28530712The microRNA miR-31 inhibits CD8<sup>+</sup> T cell function in chronic viral infection.Nat Immunol2017
28926530Erratum: The microRNA miR-31 inhibits CD8<sup>+</sup> T cell function in chronic viral infection.Nat Immunol2017
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Collaborators

Lukas Chavez
University of California San Diego
Co-authored papers 13
Patricia G McCaffrey
Harvard Medical School Boston
Co-authored papers 12
Yousang Gwack
Co-authored papers 7
Sonal Srikanth
Co-authored papers 7
Bjoern Peters
University of Washington School of Medicine
Co-authored papers 6
Jason A Greenbaum
Co-authored papers 4
Xiaole Shirley Liu
Co-authored papers 3
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Moores Cancer Center, university of california san diego
Co-authored papers 3
Jun Lu
Yale University
Co-authored papers 2
Mary L Disis
University of Washington Medicine Cancer Vaccine Institute, University of Washington
Co-authored papers 2
Iros Barozzi
Co-authored papers 2
Eduardo Vilar
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
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Co-authored papers 2
Gustavo Mostoslavsky
Co-authored papers 2
George Q Daley
Boston Children's Hospital, Harvard Medical School
Co-authored papers 2
Berthold Göttgens
Co-authored papers 2
Tom Curran
Medical University of South Carolina
Co-authored papers 2
Nathaniel Heintz
Howard Hughes Medical Institute, The Rockefeller University
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Ryan Lister
Co-authored papers 2
Patricia J Pukkila
University of North Carolina at Chapel Hill
Co-authored papers 2
Todd R Golub
Broad Institute of MIT and Harvard
Co-authored papers 2
Joseph R Ecker
The Salk Institute for Biological Studies
Co-authored papers 2
Jun Qin
Co-authored papers 2
Steven A Carr
Broad Institute of MIT and Harvard
Co-authored papers 2
Judy E Garber
Dana-Farber Cancer Institute
Co-authored papers 2
David R Liu
Co-authored papers 2
Timothy R Rebbeck
Center for Cancer Equity and Engagement, Dana-Farber/Harvard Cancer Center
Co-authored papers 2
Avrum Spira
Boston University School of Medicine
Co-authored papers 2
Cesar A Sommer
Co-authored papers 2
Roberto Spreafico
Co-authored papers 2
Release 1.2