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Author Details

Tomokatsu Ikawa
Tokyo University of Science
1999
63
35
PMIDPaper TitleJournal TitlePublished Year
37922454Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz.Blood2024
36577074Robotic data acquisition with deep learning enables cell image-based prediction of transcriptomic phenotypes.Proc Natl Acad Sci U S A2023
37266576Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis.Elife2023
35085287Different cell imaging methods did not significantly improve immune cell image classification performance.PLoS One2022
36443290PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment.Nat Commun2022
36112959Tracing the evolutionary history of blood cells to the unicellular ancestor of animals.Blood2022
32573712Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL.Blood2020
33392513Cell Fate Decisions: The Role of Transcription Factors in Early B-cell Development and Leukemia.Blood Cancer Discov2020
33357426Chromatin Protein PC4 Orchestrates B Cell Differentiation by Collaborating with IKAROS and IRF4.Cell Rep2020
31719197Single-cell transcriptomics reveals expansion of cytotoxic CD4 T cells in supercentenarians.Proc Natl Acad Sci U S A2019
29440259Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells.Genes Dev2018
29939266Kelch-like protein 14 promotes B-1a but suppresses B-1b cell development.Int Immunol2018
30344701Suppression effect on IFN-γ of adipose tissue-derived mesenchymal stem cells isolated from β2-microglobulin-deficient mice.Exp Ther Med2018
28850106FANTOM5 CAGE profiles of human and mouse samples.Sci Data2017
27406037Transient Tcf3 Gene Repression by TALE-Transcription Factor Targeting.Appl Biochem Biotechnol2016
27913604Conversion of T cells to B cells by inactivation of polycomb-mediated epigenetic suppression of the B-lineage program.Genes Dev2016
25678556Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.Science2015
26607950Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells.Stem Cell Reports2015
26711264Role of Polycomb RYBP in Maintaining the B-1-to-B-2 B-Cell Lineage Switch in Adult Hematopoiesis.Mol Cell Biol2015
26136427BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells.J Immunol2015
26238124CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.J Exp Med2015
24670764A promoter-level mammalian expression atlas.Nature2014
25344725The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program.Nat Immunol2014
25074919Zinc transporter SLC39A10/ZIP10 controls humoral immunity by modulating B-cell receptor signal strength.Proc Natl Acad Sci U S A2014
25074913Zinc transporter SLC39A10/ZIP10 facilitates antiapoptotic signaling during early B-cell development.Proc Natl Acad Sci U S A2014
24777532The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.Nat Immunol2014
24850218Genetic and epigenetic control of early lymphocyte development.Curr Top Microbiol Immunol2014
24567410Loss of mTOR complex 1 induces developmental blockage in early T-lymphopoiesis and eradicates T-cell acute lymphoblastic leukemia cells.Proc Natl Acad Sci U S A2014
23290135Regeneration of human tumor antigen-specific T cells from iPSCs derived from mature CD8(+) T cells.Cell Stem Cell2013
23893300MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors.Proc Natl Acad Sci U S A2013
22665574Runx1-Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1.J Exp Med2012
22709691Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM.Blood2012
22544934E2A and CBP/p300 act in synergy to promote chromatin accessibility of the immunoglobulin κ locus.J Immunol2012
21606479Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells.Blood2011
20023630Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells.Nature2010
20969582A map for lineage restriction of progenitors during hematopoiesis: the essence of the myeloid-based model.Immunol Rev2010
20519628Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).Blood2010
20595615An essential developmental checkpoint for production of the T cell lineage.Science2010
20207230Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.Cell Stem Cell2010
19250680Notch activation in thymic epithelial cells induces development of thymic microenvironments.Mol Immunol2009
19380810Direct hematological toxicity and illegitimate chromosomal recombination caused by the systemic activation of CreERT2.J Immunol2009
19089815Lipid-mediated presentation of MHC class II molecules guides thymocytes to the CD4 lineage.Eur J Immunol2009
18401412Adult T-cell progenitors retain myeloid potential.Nature2008
18725623Suppression of E-protein activity interferes with the development of BCR-ABL-mediated myeloproliferative disease.Proc Natl Acad Sci U S A2008
18776907Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate.Nat Immunol2008
19015306Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance.J Exp Med2008
19004799BCR-ABL-transformed GMP as myeloid leukemic stem cells.Proc Natl Acad Sci U S A2008
17698981Forced expression of Id2 in fetal thymic T cell progenitors allows some of their progeny to adopt NK cell fate.Int Immunol2007
18093539Regulation of T cell receptor beta gene rearrangements and allelic exclusion by the helix-loop-helix protein, E47.Immunity2007
16682500E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment.J Exp Med2006
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Collaborators

Hiroshi Kawamoto
Institute for Life and Medical Sciences, Kyoto University
Co-authored papers 42
Haruhiko Koseki
RIKEN Research Center for Allergy and Immunology
Co-authored papers 12
Cornelis Murre
University of California
Co-authored papers 7
Osamu Ohara
Co-authored papers 5
Yasushi Okazaki
Intractable Disease Research Center, Graduate School of Medicine, Juntendo University
Co-authored papers 4
Yoshihide Hayashizaki
Center for Integrative Medical Sciences
Co-authored papers 4
Erik Arner
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 4
Harukazu Suzuki
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Carsten O Daub
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 3
Alistair R R Forrest
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Hideya Kawaji
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Robert Passier
University of Twente
Co-authored papers 3
Akira Hasegawa
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Sugata Roy
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Beatrice Bodega
University of Milan
Co-authored papers 3
Andreas Lennartsson
Karolinska Institute
Co-authored papers 3
Hiroshi Ohno
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Dan Goldowitz
University of British Columbia
Co-authored papers 3
Michael Detmar
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 3
Naoto Kondo
Nagoya City University Graduate School of Medical Sciences
Co-authored papers 3
Peter Zhang
Child and Family Research Institute, University of British Columbia
Co-authored papers 3
Yuki I Kawamura
Research Institute, National Center for Global Health and Medicine
Co-authored papers 3
Yosuke Mizuno
Yokohama National University
Co-authored papers 3
Reto Guler
International Centre for Genetic Engineering and Biotechnology
Co-authored papers 3
Ernst J Wolvetang
Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Co-authored papers 3
Suzana Savvi
South African Medical Research Council (SAMRC), University of Cape Town
Co-authored papers 3
Soichi Ogishima
Tohoku University Graduate School of Medicine
Co-authored papers 3
Christine L Mummery
Leiden University Medical Center
Co-authored papers 3
Shigeo Koyasu
RIKEN Center for Integrative Medical Sciences (IMS)
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Jun Furusawa
Aichi Cancer Center Hospital
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Release 1.2