Author details

Full Name

CÃ©cile Lecoeur

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35283856	Processing and Subcellular Localization of the Hepatitis E Virus Replicase: Identification of Candidate Viral Factories.	Frontiers in Microbiology	2022
36007070	An Arginine-Rich Motif in the ORF2 capsid protein regulates the hepatitis E virus lifecycle and interactions with the host cell.	PLoS Pathog	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
33402679	Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
33558525	Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
31388097	The expression of genes in top obesity-associated loci is enriched in insula and substantia nigra brain regions involved in addiction and reward.	International Journal of Obesity	2020
32238601	Obesity status modifies the association between rs7556897T>C in the intergenic region SLC19A3-CCL20 and blood pressure in French children.	Clinical Chemistry and Laboratory Medicine	2020
32383070	Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood.	Eur J Epidemiol	2020
32763550	Association between schizophrenia and Toxoplasma gondii infection in Algeria.	Psychiatry Research	2020
31539074	Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study.	JAMA Netw Open	2019
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018
28580277	Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.	Molecular Metabolism	2017
28898252	Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.	PLoS Med	2017
27798627	Genome-wide analysis identifies 12 loci influencing human reproductive behavior.	Nat Genet	2016
24699409	A central role for GRB10 in regulation of islet function in man.	PLoS Genet	2014
24448642	Direct estimates of natural selection in Iberia indicate calcium absorption was not the only driver of lactase persistence in Europe.	Molecular Biology and Evolution	2014
24296717	Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity.	Diabetes	2014
24463962	Alternative human liver transcripts of TCF7L2 bind to the gluconeogenesis regulator HNF4Î± at the protein level.	Diabetologia	2014
23563607	Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.	Nat Genet	2013
22238593	A genome-wide association search for type 2 diabetes genes in African Americans.	PLoS One	2012
22701567	Whole-exome sequencing and high throughput genotyping identified KCNJ11 as the thirteenth MODY gene.	PLoS ONE	2012
22479202	Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.	PLoS Genet	2012
22698912	Impact of common variation in bone-related genes on type 2 diabetes and related traits.	Diabetes	2012
22885924	Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.	Nat Genet	2012
22343897	Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.	Nature	2012
22581228	A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.	Nat Genet	2012
22415877	No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.	Diabetes	2012
22484627	A genome-wide association meta-analysis identifies new childhood obesity loci.	Nat Genet	2012
22606236	Glucose-dependent regulation of NR2F2 promoter and influence of SNP-rs3743462 on whole body insulin sensitivity.	PLoS ONE	2012
22403646	A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.	PLoS One	2012
21427694	Differential coexpression analysis of obesity-associated networks in human subcutaneous adipose tissue.	Int J Obes (Lond)	2012
21515849	Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children.	Diabetes	2011
20966904	Lack of association of CD36 SNPs with early onset obesity: a meta-analysis in 9,973 European subjects.	Obesity (Silver Spring)	2011
21454707	Endospanins regulate a postinternalization step of the leptin receptor endocytic pathway.	Journal of Biological Chemistry	2011
20075856	Analysis of the SIM1 contribution to polygenic obesity in the French population.	Obesity (Silver Spring)	2010
20935630	Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.	Nat Genet	2010
20935629	Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.	Nat Genet	2010
20858683	Common variants at 10 genomic loci influence hemoglobin Aâ¿(C) levels via glycemic and nonglycemic pathways.	Diabetes	2010
20130649	A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.	Nature	2010
20081858	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Nat Genet	2010
20081857	Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.	Nat Genet	2010
20339530	Inflammatory role of Toll-like receptors in human and murine adipose tissue.	Mediators of Inflammation	2010
18945286	A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature.	Annals of Human Genetics	2009
19300429	A rare variant in the visfatin gene (NAMPT/PBEF1) is associated with protection from obesity.	Obesity	2009
19476617	The association of CD81 with tetraspanin-enriched microdomains is not essential for Hepatitis C virus entry.	BMC Microbiology	2009
19165163	Association studies on ghrelin and ghrelin receptor gene polymorphisms with obesity.	Obesity (Silver Spring)	2009
19292929	Functional and genetic analysis in type 2 diabetes of liver X receptor alleles--a cohort study.	BMC Medical Genetics	2009
19460888	The role of ghrelin and ghrelin-receptor gene variants and promoter activity in type 2 diabetes.	European Journal of Endocrinology	2009
19377085	The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects.	Hum Mol Genet	2009