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TKG
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Author Details
Full Name
Klaus Schughart
Affiliation
University of Tennessee Health Science Center
ORCID
Career Start Year
1982
Papers
142
H Index
37
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36423831
Inhibition of p38 signaling curtails the SARS-CoV-2 induced inflammatory response but retains the IFN-dependent antiviral defense of the lung epithelial barrier.
Antiviral Res
2023
37277327
Hamster model for post-COVID-19 alveolar regeneration offers an opportunity to understand post-acute sequelae of SARS-CoV-2.
Nat Commun
2023
34825965
Exogenous and Endogenous Triggers Differentially Stimulate Pigr Expression and Antibacterial Secretory Immunity in the Murine Respiratory Tract.
Lung
2022
36445861
Correction: Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection.
PLoS Pathog
2022
36346236
Predicting Influenza A Virus Infection in the Lung from Hematological Data with Machine Learning.
mSystems
2022
35056627
<i>Toxocara canis</i>- and <i>Toxocara cati</i>-Induced Neurotoxocarosis Is Associated with Comprehensive Brain Transcriptomic Alterations.
Microorganisms
2022
35025971
Itaconate and derivatives reduce interferon responses and inflammation in influenza A virus infection.
PLoS Pathog
2022
33275160
OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential.
Appl Microbiol Biotechnol
2021
33627703
Highly dampened blood transcriptome response in HIV patients after influenza infection.
Sci Rep
2021
33488611
Genetic Dissection of the Regulatory Mechanisms of <i>Ace2</i> in the Infected Mouse Lung.
Front Immunol
2021
33640018
Blood transcriptome analysis of patients with uncomplicated bacterial infection and sepsis.
BMC Res Notes
2021
34637789
Impaired beta-oxidation increases vulnerability to influenza A infection.
J Biol Chem
2021
34777354
The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood.
Front Immunol
2021
34453370
Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain as a novel regulator of striatal axonal branching in mice.
Genes Brain Behav
2021
33994946
Long-Term Consequence of Non-neurotropic H3N2 Influenza A Virus Infection for the Progression of Alzheimer's Disease Symptoms.
Front Cell Neurosci
2021
33941189
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles.
BMC Biol
2021
34059750
Author Correction: Highly dampened blood transcriptome response in HIV patients after respiratory infection.
Sci Rep
2021
33408218
Prospective validation study of prognostic biomarkers to predict adverse outcomes in patients with COVID-19: a study protocol.
BMJ Open
2021
32321537
H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice.
Virol J
2020
32060626
A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.
Mamm Genome
2020
33173537
<i>Pituitary Tumor Transforming Gene 1</i> Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging.
Front Genet
2020
32303635
Transcriptome profiling and protease inhibition experiments identify proteases that activate H3N2 influenza A and influenza B viruses in murine airways.
J Biol Chem
2020
32348764
Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross.
Cell Rep
2020
30429335
Endosomal Toll-Like Receptors 7 and 9 Cooperate in Detection of Murine Gammaherpesvirus 68 Infection.
J Virol
2019
31826721
Antiviral potential of human IFN-α subtypes against influenza A H3N2 infection in human lung explants reveals subtype-specific activities.
Emerg Microbes Infect
2019
31557153
Multiplex profiling of inflammation-related bioactive lipid mediators in Toxocara canis- and Toxocara cati-induced neurotoxocarosis.
PLoS Negl Trop Dis
2019
31099738
Tmprss2 knock-out mice are resistant to H10 influenza A virus pathogenesis.
J Gen Virol
2019
29487124
Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function.
J Neurosci
2018
30084768
Exchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice.
J Gen Virol
2018
29976755
TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1.
J Biol Chem
2018
29947965
Of mice and men: the host response to influenza virus infection.
Mamm Genome
2018
27811478
Deletion of Irf3 and Irf7 Genes in Mice Results in Altered Interferon Pathway Activation and Granulocyte-Dominated Inflammatory Responses to Influenza A Infection.
J Innate Immun
2017
28377766
Host Genetic Background Strongly Affects Pulmonary microRNA Expression before and during Influenza A Virus Infection.
Front Immunol
2017
28148793
Mutations during the Adaptation of H9N2 Avian Influenza Virus to the Respiratory Epithelium of Pigs Enhance Sialic Acid Binding Activity and Virulence in Mice.
J Virol
2017
29102108
Increased virulence of a PB2/HA mutant of an avian H9N2 influenza strain after three passages in porcine differentiated airway epithelial cells.
Vet Microbiol
2017
28697377
Absence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease.
Neurobiol Aging
2017
28619954
A novel immune biomarker <i>IFI27</i> discriminates between influenza and bacteria in patients with suspected respiratory infection.
Eur Respir J
2017
27933529
QTL Mapping and Identification of Candidate Genes in DO Mice: A Use Case Model Derived from a Benzene Toxicity Experiment.
Methods Mol Biol
2017
26969150
TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency virus infection and correlates to CD4 counts and virus loads.
Retrovirology
2016
27193691
Genetically diverse CC-founder mouse strains replicate the human influenza gene expression signature.
Sci Rep
2016
27405649
Identification of specific residues in avian influenza A virus NS1 that enhance viral replication and pathogenicity in mammalian systems.
J Gen Virol
2016
26889029
The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.
J Virol
2016
27088501
Respiratory Mucosal Proteome Quantification in Human Influenza Infections.
PLoS One
2016
26817701
Lst1 deficiency has a minor impact on course and outcome of the host response to influenza A H1N1 infections in mice.
Virol J
2016
26921172
Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.
BMC Genomics
2016
25843806
Microarray gene expression analysis reveals major differences between Toxocara canis and Toxocara cati neurotoxocarosis and involvement of T. canis in lipid biosynthetic processes.
Int J Parasitol
2015
26329040
RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infection.
BMC Genomics
2015
26716013
CD11b(+)Ly6C(++)Ly6G(-) Cells with Suppressive Activity Towards T Cells Accumulate in Lungs of Influenza a Virus-Infected Mice.
Eur J Microbiol Immunol (Bp)
2015
26047817
Hematological parameters in the early phase of influenza A virus infection in differentially susceptible inbred mouse strains.
BMC Res Notes
2015
26202236
Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background.
J Virol
2015
1 - 50 of 142
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