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Author Details

Clare Baecher-Allan
Brigham and Women's Hospital, Harvard Medical School
1988
61
36
PMIDPaper TitleJournal TitlePublished Year
36533976Safety and activity of anti-CD14 antibody IC14 (atibuclimab) in ALS: Experience with expanded access protocol.Muscle Nerve2023
37057191Preserved T cell but attenuated antibody response in MS patients on fingolimod and ocrelizumab following 2nd and 3rd SARS-CoV-2 mRNA vaccine.Mult Scler J Exp Transl Clin2023
37175706Defective Induction of IL-27-Mediated Immunoregulation by Myeloid DCs in Multiple Sclerosis.Int J Mol Sci2023
36881624Nasal administration of anti-CD3 mAb (Foralumab) downregulates <i>NKG7</i> and increases <i>TGFB1</i> and <i>GIMAP7</i> expression in T cells in subjects with COVID-19.Proc Natl Acad Sci U S A2023
35095916Corrigendum: Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study.Front Immunol2022
36505477Nasal administration of anti-CD3 monoclonal antibody modulates effector CD8+ T cell function and induces a regulatory response in T cells in human subjects.Front Immunol2022
34475873Nasal Administration of Anti-CD3 Monoclonal Antibody (Foralumab) Reduces Lung Inflammation and Blood Inflammatory Biomarkers in Mild to Moderate COVID-19 Patients: A Pilot Study.Front Immunol2021
31326977Highly differentiated cytotoxic T cells in inclusion body myositis.Brain2019
29323143Optimizing human Treg immunotherapy by Treg subset selection and E-selectin ligand expression.Sci Rep2018
29470968Multiple Sclerosis: Mechanisms and Immunotherapy.Neuron2018
29358315Effector T Cells in Multiple Sclerosis.Cold Spring Harb Perspect Med2018
29763776Dimethyl fumarate downregulates the immune response through the HCA<sub>2</sub>/GPR109A pathway: Implications for the treatment of multiple sclerosis.Mult Scler Relat Disord2018
25637022Nonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR-CD25hiCD127lo Tregs in multiple sclerosis and in response to IL-6.J Immunol2015
24968232Regulation of gene expression in autoimmune disease loci and the genetic basis of proliferation in CD4+ effector memory T cells.PLoS Genet2014
24191009Application of user-guided automated cytometric data analysis to large-scale immunoprofiling of invariant natural killer T cells.Proc Natl Acad Sci U S A2013
22560445Human epidermal Langerhans cells maintain immune homeostasis in skin by activating skin resident regulatory T cells.Immunity2012
20888750Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine.Biosens Bioelectron2011
21540856Identification of T helper type 1-like, Foxp3+ regulatory T cells in human autoimmune disease.Nat Med2011
21300823CD2 costimulation reveals defective activity by human CD4+CD25(hi) regulatory cells in patients with multiple sclerosis.J Immunol2011
19756989Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells.J Clin Immunol2010
20498357TGF-beta induces IL-9 production from human Th17 cells.J Immunol2010
19237575The role of the CD58 locus in multiple sclerosis.Proc Natl Acad Sci U S A2009
19801510Cutting Edge: Responder T cells regulate human DR+ effector regulatory T cell activity via granzyme B.J Immunol2009
19443687Automated high-dimensional flow cytometric data analysis.Proc Natl Acad Sci U S A2009
19171879IL-17-producing human peripheral regulatory T cells retain suppressive function.Blood2009
19155502Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses.J Immunol2009
18395861Human regulatory T cells and autoimmunity.Eur J Immunol2008
18763026Multiple sclerosis and regulatory T cells.J Clin Immunol2008
18469800IL-21 and TGF-beta are required for differentiation of human T(H)17 cells.Nature2008
17475842Up-regulation of gene related to anergy in lymphocytes is associated with Notch-mediated human T cell suppression.J Immunol2007
16378733Regulatory cells and human cancer.Semin Cancer Biol2006
18432975The purification and functional analysis of human CD4+CD25high regulatory T cells.Curr Protoc Immunol2006
16762596Human CD25high Tregs: isolation by beads versus by FACS sorting.Clin Immunol2006
16903916Human regulatory T cells and their role in autoimmune disease.Immunol Rev2006
16464567Immune regulation in tumor-bearing hosts.Curr Opin Immunol2006
16585553MHC class II expression identifies functionally distinct human regulatory T cells.J Immunol2006
15790361Multiple sclerosis.Immunol Rev2005
16214081Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+CD25+ T cells.Clin Immunol2005
15870015Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4+ CD25+ T cells.Clin Immunol2005
15893699Characterization of in vivo expanded OspA-specific human T-cell clones.Clin Immunol2005
15067033Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis.J Exp Med2004
15280423Suppressor T cells in human diseases.J Exp Med2004
15153541T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis.J Immunol2004
15036232Human CD4+CD25+ regulatory T cells.Semin Immunol2004
12594850Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis.Eur J Immunol2003
14609213CD4+CD25+ regulatory cells from human peripheral blood express very high levels of CD25 ex vivo.Novartis Found Symp2003
11893659Mapping susceptibility genes for the induction of pulmonary fibrosis in mice.Chest2002
12444126Inhibition of human CD4(+)CD25(+high) regulatory T cell function.J Immunol2002
11466340CD4+CD25high regulatory cells in human peripheral blood.J Immunol2001
10775503Serpins identified as cell growth inhibitors in human plasma.Mol Cell Biol Res Commun2000
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Collaborators

David A Hafler
Yale School of Medicine, Yale School of Public Health
Co-authored papers 26
Howard L Weiner
Co-authored papers 11
Philip L De Jager
Columbia University Medical Center
Co-authored papers 6
Saef Izzy
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 3
Soumya Raychaudhuri
Brigham and Women's Hospital and Harvard Medical School
Co-authored papers 2
Michael B Brenner
Co-authored papers 2
Elizabeth J Rossin
Co-authored papers 2
Russell Griffin
University of Alabama Birmingham
Co-authored papers 2
Jack L Pinkus
Brigham and Women's Hospital Department of Neurology, and Harvard Medical School
Co-authored papers 1
Pablo Tamayo
University of California San Diego
Co-authored papers 1
Kristin M Galetta
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Jorge R Oksenberg
Co-authored papers 1
Cristin Aubin
Co-authored papers 1
Stephen S Rich
Co-authored papers 1
William W Kwok
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Co-authored papers 1
An Goris
Co-authored papers 1
Margaret A Pericak-Vance
Co-authored papers 1
Graeme J Stewart
Co-authored papers 1
Steven M Greenberg
Massachusetts General Hospital
Co-authored papers 1
Aarno Palotie
Co-authored papers 1
Alkes L Price
Broad Institute of MIT and Harvard
Co-authored papers 1
Leena Peltonen
Co-authored papers 1
Mark J Daly
Massachusetts General Hospital
Co-authored papers 1
Virpi Leppä
Co-authored papers 1
Paul I W de Bakker
Vertex Pharmaceuticals
Co-authored papers 1
Lars Klareskog
Co-authored papers 1
Stephen Sawcer
Co-authored papers 1
Kamil Slowikowski
Co-authored papers 1
Roman Yelensky
Co-authored papers 1
Alastair Compston
Co-authored papers 1
Release 1.2