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Author Details

Lorenz Studer
The Center for Stem Cell Biology, Memorial Sloan Kettering Cancer Center
1994
181
75
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36824730Generation of human cerebral organoids with a structured outer subventricular zone.bioRxiv2023
37553760GABA Regulates Electrical Activity and Tumor Initiation in Melanoma.Cancer Discov2023
37503189The SATB1-MIR22-GBA axis mediates glucocerebroside accumulation inducing a cellular senescence-like phenotype in dopaminergic neurons.bioRxiv2023
37461485Identifying novel age-modulating compounds and quantifying cellular aging using novel computational framework for evaluating transcriptional age.bioRxiv2023
36993570Genipin Crosslinks the Extracellular Matrix to Rescue Developmental and Degenerative Defects, and Accelerates Regeneration of Peripheral Neurons.bioRxiv2023
37083451Encephalitis and poor neuronal death-mediated control of herpes simplex virus in human inherited RIPK3 deficiency.Sci Immunol2023
37034664TNF-NFkB-p53 axis restricts in vivo survival of hPSC-derived dopamine neuron.bioRxiv2023
37267920Retraction Notice to: Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells.Cell Stem Cell2023
36868194hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's disease.Cell Stem Cell2023
36302757Transient inhibition of p53 enhances prime editing and cytosine base-editing efficiencies in human pluripotent stem cells.Nat Commun2022
35434558A dual <i>SHOX2:GFP; MYH6:mCherry</i> knockin hESC reporter line for derivation of human SAN-like cells.iScience2022
35667922Induced pluripotent stem cells: a tool for modeling Parkinson's disease.Trends Neurosci2022
35355015Anatomic position determines oncogenic specificity in melanoma.Nature2022
36171373A nomenclature consensus for nervous system organoids and assembloids.Nature2022
33393505TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons.J Clin Invest2021
33545080Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01.Cell Stem Cell2021
33545081Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use.Cell Stem Cell2021
33542154Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate.Proc Natl Acad Sci U S A2021
33558694Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease.Nat Neurosci2021
34642326Author Correction: Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia.Nat Commun2021
34425410Neuron-intrinsic immunity to viruses in mice and humans.Curr Opin Immunol2021
34478629Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3.Cell Stem Cell2021
34417458Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.Nat Commun2021
33941615Disabling the Fanconi Anemia Pathway in Stem Cells Leads to Radioresistance and Genomic Instability.Cancer Res2021
34301951Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia.Nat Commun2021
34031650SARS-CoV-2 Infection Causes Dopaminergic Neuron Senescence.Res Sq2021
33336840Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions.Genes Chromosomes Cancer2021
33398129Human stem cell models to study host-virus interactions in the central nervous system.Nat Rev Immunol2021
32457462Parkinson's disease grafts benefit from well-timed growth factor.Nature2020
31949159The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.Nat Commun2020
32579880A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids.Cell Stem Cell2020
32745521Accelerated transsulfuration metabolically defines a discrete subclass of amyotrophic lateral sclerosis patients.Neurobiol Dis2020
32903681Pluripotent Stem Cell Therapies for Parkinson Disease: Present Challenges and Future Opportunities.Front Cell Dev Biol2020
32619517A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes.Cell Stem Cell2020
31160395Corrigendum: TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency.Genes Dev2019
31806906Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis.Nat Med2019
31543366Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons.Cell Stem Cell2019
31155483Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs.Cell Stem Cell2019
30804533NFIA is a gliogenic switch enabling rapid derivation of functional human astrocytes from pluripotent stem cells.Nat Biotechnol2019
30911172Derivation of enteric neuron lineages from human pluripotent stem cells.Nat Protoc2019
30936566Specification of positional identity in forebrain organoids.Nat Biotechnol2019
30962586Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder.Nat Biomed Eng2019
29784997Mechanics-guided embryonic patterning of neuroectoderm tissue from human pluripotent stem cells.Nat Mater2018
30154162Human iPSC-derived trigeminal neurons lack constitutive TLR3-dependent immunity that protects cortical neurons from HSV-1 infection.Proc Natl Acad Sci U S A2018
30115631TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency.Genes Dev2018
30061297Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ).Dis Model Mech2018
30341316HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.Nat Commun2018
30446643A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival.Nat Commun2018
29474921Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.Cell2018
26592774Back and forth in time: Directing age in iPSC-derived lineages.Brain Res2017
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Collaborators

Co-authored papers 11
Co-authored papers 9
Co-authored papers 9
John Van Geest Center for Brain Repair, University of Cambridge
Co-authored papers 5
Memorial Sloan Kettering Cancer Center
Co-authored papers 5
Boston Children's Hospital, Harvard Medical School
Co-authored papers 4
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
Weill Cornell Medical College.
Co-authored papers 4
New York State Psychiatric Institute, Research Foundation for Mental Hygiene
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Caryl and Israel Englander Institute for Precision Medicine.
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
RIKEN Center for Biosystems Dynamics Research
Co-authored papers 3
Co-authored papers 3
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 3
McGill University
Co-authored papers 3
Co-authored papers 3
Faculty of Law and School of Public Health, University of Alberta
Co-authored papers 3
Weill Cornell Medical College
Co-authored papers 3
Johns Hopkins University, Berman Institute of Bioethics
Co-authored papers 3
Center for Bioethics, Harvard Medical School
Co-authored papers 3
Department of Pediatrics/Rady Children's Hospital, University of California San Diego
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Co-authored papers 2
Graduate School of Medicine, Kyoto University
Co-authored papers 2
Co-authored papers 2
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 2
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Center for iPS Cell Research and Application, Kyoto University
Co-authored papers 2