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Author Details

Elena Harjes
Massey University
2006
26
13
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36824964Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.bioRxiv2023
37821454Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.Nat Commun2023
37531216NMR Shows Why a Small Chemical Change Almost Abolishes the Antimicrobial Activity of Glycocin F.Biochemistry2023
37282621Seven-membered ring nucleobases as inhibitors of human cytidine deaminase and APOBEC3A.Org Biomol Chem2023
36302365Design, Synthesis, and Evaluation of a Cross-Linked Oligonucleotide as the First Nanomolar Inhibitor of APOBEC3A.Biochemistry2022
36146779Small-Angle X-ray Scattering (SAXS) Measurements of APOBEC3G Provide Structural Basis for Binding of Single-Stranded DNA and Processivity.Viruses2022
33156522Experimentally based structural model of Yih1 provides insight into its function in controlling the key translational regulator Gcn2.FEBS Lett2021
33673243Small-Angle X-ray Scattering Models of APOBEC3B Catalytic Domain in a Complex with a Single-Stranded DNA Inhibitor.Viruses2021
33283398Cyclic peptides bearing the d-Phe-2-Abz turn motif: Structural characterization and antimicrobial potential.J Pept Sci2021
31633265Differential Inhibition of APOBEC3 DNA-Mutator Isozymes by Fluoro- and Non-Fluoro-Substituted 2'-Deoxyzebularine Embedded in Single-Stranded DNA.Chembiochem2020
30418757Inhibiting APOBEC3 Activity with Single-Stranded DNA Containing 2'-Deoxyzebularine Analogues.Biochemistry2019
31603457Selective inhibition of APOBEC3 enzymes by single-stranded DNAs containing 2'-deoxyzebularine.Org Biomol Chem2019
29900628Acyclic peptides incorporating the d-Phe-2-Abz turn motif: Investigations on antimicrobial activity and propensity to adopt β-hairpin conformations.J Pept Sci2018
29140694Tyrocidine A Analogues Bearing the Planar d-Phe-2-Abz Turn Motif: How Conformation Impacts Bioactivity.J Med Chem2017
28369637NMR-based method of small changes reveals how DNA mutator APOBEC3A interacts with its single-stranded DNA substrate.Nucleic Acids Res2017
29098772Crystal and NMR Structures of a Peptidomimetic β-Turn That Provides Facile Synthesis of 13-Membered Cyclic Tetrapeptides.Chem Asian J2017
23318957Dispersed sites of HIV Vif-dependent polyubiquitination in the DNA deaminase APOBEC3F.J Mol Biol2013
23596292Impact of H216 on the DNA binding and catalytic activities of the HIV restriction factor APOBEC3G.J Virol2013
22879380Structure of the RNA claw of the DNA packaging motor of bacteriophage Φ29.Nucleic Acids Res2012
24832226A Comparison of Two Single-Stranded DNA Binding Models by Mutational Analysis of APOBEC3G.Biology (Basel)2012
21430060Identification of a single amino acid required for APOBEC3 antiretroviral cytidine deaminase activity.J Virol2011
20152150Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces.Structure2010
20971849A single amino acid in human APOBEC3F alters susceptibility to HIV-1 Vif.J Biol Chem2010
19389408An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model.J Mol Biol2009
18288108Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G.Nature2008
16698549GTP-Ras disrupts the intramolecular complex of C1 and RA domains of Nore1.Structure2006
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Collaborators

Reuben S Harris
University of Texas Health San Antonio
Co-authored papers 11
Hiroshi Matsuo
Frederick National Laboratory for Cancer Research
Co-authored papers 9
Keisuke Shindo
Graduate School of Medicine, Kyoto University
Co-authored papers 5
Ming Li
Department of Cancer Research Institute, University of South Australia
Co-authored papers 3
John S Albin
Massachusetts General Hospital
Co-authored papers 2
Timothy M Ryan
Pennsylvania State University, State College
Co-authored papers 2
Daniel A Harki
University of Minnesota
Co-authored papers 2
William L Brown
University of Minnesota
Co-authored papers 2
Mohan Somasundaran
University of Massachusetts Chan Medical School
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
Mary Munson
University of Massachusetts Chan Medical School
Co-authored papers 1
Rebecca S LaRue
Minnesota Supercomputing Institute, University of Minnesota
Co-authored papers 1
John D Gross
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 1
Linda Chelico
University of Saskatchewan, College of Medicine
Co-authored papers 1
Marc C Morais
University of Texas Medical Branch
Co-authored papers 1
Peter Bayer
University of Duisburg-Essen
Co-authored papers 1
Shivender M D Shandilya
University of Massachusetts Medical School
Co-authored papers 1
John S Anderson
Co-authored papers 1
Celia A Schiffer
University of Massachusetts Chan Medical School
Co-authored papers 1
Release 1.2