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Author Details

Otto Sanchez
Ontario Tech University
1973
80
34
PMIDPaper TitleJournal TitlePublished Year
35795020Lost in machine translation: The promises and pitfalls of machine translation for multilingual group work in global health education.Discov Educ2022
34196309Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.J Clin Invest2021
33529165RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.J Clin Invest2021
31371388Metalloprotease inhibitor TIMP proteins control FGF-2 bioavailability and regulate skeletal growth.J Cell Biol2019
30222135Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.J Clin Invest2018
28526225The acute response to interval and continuous exercise in adults with confirmed airway hyper-responsiveness.J Sci Med Sport2017
26876210Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation.Oncogene2016
24858046Cooperation of Blm and Mus81 in development, fertility, genomic integrity and cancer suppression.Oncogene2015
26057431Using wikis to stimulate collaborative learning in two online health sciences courses.J Nurs Educ2015
25807548Timp3 deficient mice show resistance to developing breast cancer.PLoS One2015
25347747TIMP3 controls cell fate to confer hepatocellular carcinoma resistance.Oncogene2015
24762360Environmental factors in an Ontario community with disparities in colorectal cancer incidence.Glob J Health Sci2014
23382699Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis.PLoS Genet2013
23449389The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover.Cell Death Differ2013
22193722Reduced 4-aminobiphenyl-induced liver tumorigenicity but not DNA damage in arylamine N-acetyltransferase null mice.Cancer Lett2012
22343728Caspase-8 is essential for maintaining chromosomal stability and suppressing B-cell lymphomagenesis.Blood2012
21552324Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome.PLoS Genet2011
22006951Caspase-8 inactivation in T cells increases necroptosis and suppresses autoimmunity in Bim-/- mice.J Cell Biol2011
22125490Role of Pirh2 in mediating the regulation of p53 and c-Myc.PLoS Genet2011
20385750Rnf8 deficiency impairs class switch recombination, spermatogenesis, and genomic integrity and predisposes for cancer.J Exp Med2010
20697156Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice.J Clin Invest2010
19008920Essential role for Bclaf1 in lung development and immune system function.Cell Death Differ2009
17875692Functional interplay of p53 and Mus81 in DNA damage responses and cancer.Cancer Res2007
16572175Regulation of cancer cell migration and bone metastasis by RANKL.Nature2006
16702949Enhanced metastatic dissemination to multiple organs by melanoma and lymphoma cells in timp-3-/- mice.Oncogene2006
16107613RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis.Genes Dev2005
15971261van den Ende-Gupta syndrome of blepharophimosis, arachnodactyly, and congenital contractures.Am J Med Genet A2005
16037568Combination of tumor necrosis factor-alpha ablation and matrix metalloproteinase inhibition prevents heart failure after pressure overload in tissue inhibitor of metalloproteinase-3 knock-out mice.Circ Res2005
15131084Collaboration of Brca1 and Chk2 in tumorigenesis.Genes Dev2004
15194047A conditionally replicating adenovirus for nasopharyngeal carcinoma gene therapy.Mol Ther2004
15205536Involvement of mammalian Mus81 in genome integrity and tumor suppression.Science2004
15336653Potential utility of BimS as a novel apoptotic therapeutic molecule.Mol Ther2004
15322543Abnormal TNF activity in Timp3-/- mice leads to chronic hepatic inflammation and failure of liver regeneration.Nat Genet2004
14747659Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten.Proc Natl Acad Sci U S A2004
14767369Insights into novel biological mediators of clinical manifestations in cancer.AACN Clin Issues2004
12815845[Moebius syndrome due to the use of misoprostol. Case report].Invest Clin2003
14560016Cbl-3-deficient mice exhibit normal epithelial development.Mol Cell Biol2003
14664799Efficacy of targeted FasL in nasopharyngeal carcinoma.Mol Ther2003
12584565Transgenic overexpression of IGF-II induces spontaneous lung tumors: a model for human lung adenocarcinoma.Oncogene2003
11552509[The hemangioma-sternum bifidum malformation syndrome. Report of a patient].Invest Clin2001
11294030[Trisomy 21. Report of 2 cases with unusual karyotypes].Invest Clin2001
11245487Anoikis and metastatic potential of cloudman S91 melanoma cells.Cancer Res2001
11560951Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3).J Clin Invest2001
10832181A systematic review of the effectiveness of environmental awareness interventions.Can J Public Health2000
11315099Expression of bone sialoprotein and osteopontin in breast cancer bone metastases.Clin Exp Metastasis2000
9929985A single-nucleotide polymorphism in the human bone morphogenetic protein-4 (BMP 4) gene.J Hum Genet1999
10390952[Achondroplasia and Down syndrome in the same patient. Report of a case].Invest Clin1999
10417287Localization of a gene for familial patella aplasia-hypoplasia (PTLAH) to chromosome 17q21-22.Am J Hum Genet1999
10068210Transgenic TIMP-1 inhibits simian virus 40 T antigen-induced hepatocarcinogenesis by impairment of hepatocellular proliferation and tumor angiogenesis.Lab Invest1999
9772279Genetic background influences timing, morphology and dissemination of lymphomas in p53-deficient mice.Int J Oncol1998
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Collaborators

Princess Margaret Cancer Centre, University Health Network
Co-authored papers 24
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 16
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 16
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
University of Sao Paulo
Co-authored papers 4
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 3
Research Institute, Princess Margaret Cancer Centre
Co-authored papers 3
Schroeder Arthritis Institute
Co-authored papers 3
th Hospital
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 3
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 2
University Health Network
Co-authored papers 2
University of Toronto
Co-authored papers 2
Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network
Co-authored papers 2
Schroeder Arthritis Institute
Co-authored papers 2
Children's Hospital Research Foundation
Co-authored papers 2
The Lunenfeld-Tannenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 2
University Health Network, University of Toronto
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 2
University of Toronto
Co-authored papers 2
Princess Margaret Cancer Centre/University Health Network, University of Toronto
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University Health Network
Co-authored papers 2
Princess Margaret Cancer Centre/University Health Network
Co-authored papers 2
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Beihua University
Co-authored papers 1