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Author Details
Full Name
David Sachs
Affiliation
Icahn School of Medicine at Mount Sinai
ORCID
Career Start Year
2013
Papers
29
H Index
21
Expertise
CM4AI Collaborator
Nevan J Krogan (CM4AI)
PMID
Paper Title
Journal Title
Published Year
35325615
PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.
Cell Stem Cell
2022
35325615
PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.
Cell Stem Cell
2022
33577760
Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity.
Immunity
2021
33577760
Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity.
Immunity
2021
32416070
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Cell
2020
32416070
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
Cell
2020
33035269
Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity.
PLoS Pathog
2020
33035269
Genome-wide transposon mutagenesis of paramyxoviruses reveals constraints on genomic plasticity.
PLoS Pathog
2020
31557312
Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture.
FEBS Lett
2019
31851929
Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses.
Cell Rep
2019
31557312
Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic coculture.
FEBS Lett
2019
31851929
Viral Fitness Landscapes in Diverse Host Species Reveal Multiple Evolutionary Lines for the NS1 Gene of Influenza A Viruses.
Cell Rep
2019
29339472
miRNA-mediated targeting of human cytomegalovirus reveals biological host and viral targets of IE2.
Proc Natl Acad Sci U S A
2018
29339472
miRNA-mediated targeting of human cytomegalovirus reveals biological host and viral targets of IE2.
Proc Natl Acad Sci U S A
2018
28658212
RNase III nucleases from diverse kingdoms serve as antiviral effectors.
Nature
2017
28469811
Factors associated with success of telaprevir- and boceprevir-based triple therapy for hepatitis C virus infection.
World J Hepatol
2017
28642329
Experimental and Computational Insight Into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity.
Circ Res
2017
28813663
A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor.
Cell Rep
2017
28658212
RNase III nucleases from diverse kingdoms serve as antiviral effectors.
Nature
2017
28515302
Transposon Mutagenesis of the Zika Virus Genome Highlights Regions Essential for RNA Replication and Restricted for Immune Evasion.
J Virol
2017
28469811
Factors associated with success of telaprevir- and boceprevir-based triple therapy for hepatitis C virus infection.
World J Hepatol
2017
28813663
A CRISPR Activation Screen Identifies a Pan-avian Influenza Virus Inhibitory Host Factor.
Cell Rep
2017
28515302
Transposon Mutagenesis of the Zika Virus Genome Highlights Regions Essential for RNA Replication and Restricted for Immune Evasion.
J Virol
2017
28642329
Experimental and Computational Insight Into Human Mesenchymal Stem Cell Paracrine Signaling and Heterocellular Coupling Effects on Cardiac Contractility and Arrhythmogenicity.
Circ Res
2017
27001854
Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity.
Proc Natl Acad Sci U S A
2016
27142077
Differences in Early Cytokine Production Are Associated With Development of a Greater Number of Symptoms Following West Nile Virus Infection.
J Infect Dis
2016
26789921
Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.
Immunity
2016
27001854
Club cells surviving influenza A virus infection induce temporary nonspecific antiviral immunity.
Proc Natl Acad Sci U S A
2016
27142077
Differences in Early Cytokine Production Are Associated With Development of a Greater Number of Symptoms Following West Nile Virus Infection.
J Infect Dis
2016
26789921
Targeting Viral Proteostasis Limits Influenza Virus, HIV, and Dengue Virus Infection.
Immunity
2016
25163420
Comparison of [¹¹C]choline ([¹¹C]CHO) and S(+)-β-methyl-[¹¹C]choline ([¹¹C]SMC) as imaging probes for prostate cancer in a PC-3 prostate cancer xenograft model.
Mol Imaging Biol
2015
26651947
microRNA Function Is Limited to Cytokine Control in the Acute Response to Virus Infection.
Cell Host Microbe
2015
26004185
Mutational Analysis of Measles Virus Suggests Constraints on Antigenic Variation of the Glycoproteins.
Cell Rep
2015
26549455
Engineered Mammalian RNAi Can Elicit Antiviral Protection that Negates the Requirement for the Interferon Response.
Cell Rep
2015
26074083
In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus.
Cell Rep
2015
25163420
Comparison of [¹¹C]choline ([¹¹C]CHO) and S(+)-β-methyl-[¹¹C]choline ([¹¹C]SMC) as imaging probes for prostate cancer in a PC-3 prostate cancer xenograft model.
Mol Imaging Biol
2015
26651947
microRNA Function Is Limited to Cytokine Control in the Acute Response to Virus Infection.
Cell Host Microbe
2015
26549455
Engineered Mammalian RNAi Can Elicit Antiviral Protection that Negates the Requirement for the Interferon Response.
Cell Rep
2015
26074083
In Vivo RNAi Screening Identifies MDA5 as a Significant Contributor to the Cellular Defense against Influenza A Virus.
Cell Rep
2015
26004185
Mutational Analysis of Measles Virus Suggests Constraints on Antigenic Variation of the Glycoproteins.
Cell Rep
2015
24275658
Mitogen-activated protein kinase-mediated licensing of interferon regulatory factor 3/7 reinforces the cell response to virus.
J Biol Chem
2014
25456074
Influenza A virus transmission bottlenecks are defined by infection route and recipient host.
Cell Host Microbe
2014
24275658
Mitogen-activated protein kinase-mediated licensing of interferon regulatory factor 3/7 reinforces the cell response to virus.
J Biol Chem
2014
24953656
The Mammalian response to virus infection is independent of small RNA silencing.
Cell Rep
2014
25135297
Long-term survival of influenza virus infected club cells drives immunopathology.
J Exp Med
2014
25065814
Costs of telaprevir-based triple therapy for hepatitis C: $189,000 per sustained virological response.
Hepatology
2014
24778219
Drosha as an interferon-independent antiviral factor.
Proc Natl Acad Sci U S A
2014
25456074
Influenza A virus transmission bottlenecks are defined by infection route and recipient host.
Cell Host Microbe
2014
25065814
Costs of telaprevir-based triple therapy for hepatitis C: $189,000 per sustained virological response.
Hepatology
2014
25135297
Long-term survival of influenza virus infected club cells drives immunopathology.
J Exp Med
2014
1 - 50 of 58
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University of Pennsylvania
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Randy A Albrecht
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Co-authored papers
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University of California berkeley
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Carlos-Filipe Pereira
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Rafael Dariolli
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Madhavika N Serasinghe
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Kateri A Moore
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Laura Campisi
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