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Author Details

Robert A Brodsky
Sidney Kimmel Cancer Center, Johns Hopkins University
1958
278
62
Prashant Mali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37675516Uniform conditioning regardless of donor in bone marrow transplantation for severe aplastic anemia.Haematologica2024
36244884Combining PTCy and ATG for GvHD prophylaxis in non-malignant diseases.Blood Rev2023
37874560ADP: the missing link between thrombosis and hemolysis.Blood Adv2023
37722353Evaluating complement dysregulation in livedoid vasculopathy using a functional assay.Blood Adv2023
37216688Silent cerebral infarction during immune TTP remission: prevalence, predictors, and impact on cognition.Blood2023
37084383Alternative donor BMT with posttransplant cyclophosphamide as initial therapy for acquired severe aplastic anemia.Blood2023
36947859A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism.Blood2023
37099066Novel Functional Assay to Characterize Mutations in Alternative Pathway of Complement.J Clin Immunol2023
36519328Biosimilars in rare diseases: a focus on paroxysmal nocturnal hemoglobinuria.Haematologica2023
36108594Concomitant Immunosuppressive Therapy and Eculizumab Use in Patients with Paroxysmal Nocturnal Hemoglobinuria: An International PNH Registry Analysis.Acta Haematol2023
32338085A review of the alternative pathway of complement and its relation to HELLP syndrome: is it time to consider HELLP syndrome a disease of the alternative pathway.J Matern Fetal Neonatal Med2022
35349667Pegcetacoplan for paroxysmal nocturnal hemoglobinuria.Blood2022
35663504The importance of terminal complement inhibition in paroxysmal nocturnal hemoglobinuria.Ther Adv Hematol2022
35907408Haploidentical bone marrow transplantation in patients with relapsed or refractory severe aplastic anaemia in the USA (BMT CTN 1502): a multicentre, single-arm, phase 2 trial.Lancet Haematol2022
35932324Maternal and fetal outcomes of pregnancy occurring after a diagnosis of immune-mediated thrombotic thrombocytopenic purpura.Ann Hematol2022
35980222The role of the alternative pathway in paroxysmal nocturnal hemoglobinuria and emerging treatments.Expert Rev Clin Pharmacol2022
35914225C5 inhibition allows continued antineoplastic therapy in cancer- and chemotherapy-associated thrombotic microangiopathy.Blood Adv2022
35282949Updates in the Management of Warm Autoimmune Hemolytic Anemia.Hematol Oncol Clin North Am2022
35259252SARS-CoV-2 vaccination and immune thrombotic thrombocytopenic purpura.Blood2022
34923628Lactate dehydrogenase versus haemoglobin: which one is the better marker in paroxysmal nocturnal haemoglobinuria?Br J Haematol2022
34461629Cardiovascular disease is a leading cause of mortality among TTP survivors in clinical remission.Blood Adv2022
34800310A 15-year, single institution experience of anticoagulation management in paroxysmal nocturnal hemoglobinuria patients on terminal complement inhibition with history of thromboembolism.Am J Hematol2022
34289657Complement dysregulation is associated with severe COVID-19 illness.Haematologica2022
32881236Antiphospholipid syndrome: Complement activation, complement gene mutations, and therapeutic implications.J Thromb Haemost2021
33683339Outcomes of a clinician-directed protocol for discontinuation of complement inhibition therapy in atypical hemolytic uremic syndrome.Blood Adv2021
33765418Factor B inhibition for paroxysmal nocturnal haemoglobinuria.Lancet Haematol2021
33512400How I treat paroxysmal nocturnal hemoglobinuria.Blood2021
33674866Pain Experiences of Adults With Sickle Cell Disease and Hematopoietic Stem Cell Transplantation: A Qualitative Study.Pain Med2021
33845193Genetic justification of severe COVID-19 using a rigorous algorithm.Clin Immunol2021
34460124Major adverse cardiovascular events in survivors of immune-mediated thrombotic thrombocytopenic purpura.Am J Hematol2021
34561473PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression.Sci Rep2021
33956069Eculizumab and aHUS: to stop or not.Blood2021
34314483Phase 2 study of danicopan in patients with paroxysmal nocturnal hemoglobinuria with an inadequate response to eculizumab.Blood2021
33945618COVID-19 vaccines induce severe hemolysis in paroxysmal nocturnal hemoglobinuria.Blood2021
31949012Characterization of breakthrough hemolysis events observed in the phase 3 randomized studies of ravulizumab versus eculizumab in adults with paroxysmal nocturnal hemoglobinuria.Haematologica2021
33179792Reduced sensitivity of PLASMIC and French scores for the diagnosis of thrombotic thrombocytopenic purpura in older individuals.Transfusion2021
33121236Danicopan: an oral complement factor D inhibitor for paroxysmal nocturnal hemoglobinuria.Haematologica2021
31197070Sequential cellular niches control the generation of enucleated erythrocytes from human pluripotent stem cells.Haematologica2020
31812994Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS.Blood2020
31738187Are genetic approaches still needed to cure sickle cell disease?J Clin Invest2020
33464651C3 inhibition with pegcetacoplan in subjects with paroxysmal nocturnal hemoglobinuria treated with eculizumab.Am J Hematol2020
33148511Ex vivo assays to detect complement activation in complementopathies.Clin Immunol2020
32856539Cost burden of breakthrough hemolysis in patients with paroxysmal nocturnal hemoglobinuria receiving ravulizumab versus eculizumab.Hematology2020
32961372Thrombotic Microangiopathy after Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis.Biol Blood Marrow Transplant2020
32793201Properdin Is a Key Player in Lysis of Red Blood Cells and Complement Activation on Endothelial Cells in Hemolytic Anemias Caused by Complement Dysregulation.Front Immunol2020
32877502Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition.Blood2020
32818556Shortened-Duration Immunosuppressive Therapy after Nonmyeloablative, Related HLA-Haploidentical or Unrelated Peripheral Blood Grafts and Post-Transplantation Cyclophosphamide.Biol Blood Marrow Transplant2020
32813874Myeloablative haploidentical BMT with posttransplant cyclophosphamide for hematologic malignancies in children and adults.Blood Adv2020
32449174Pharmacokinetic and pharmacodynamic effects of ravulizumab and eculizumab on complement component 5 in adults with paroxysmal nocturnal haemoglobinuria: results of two phase 3 randomised, multicentre studies.Br J Haematol2020
32310222Complementopathies and precision medicine.J Clin Invest2020
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Collaborators

Richard J Jones
Sidney Kimmel Cancer Center, Johns Hopkins University
Co-authored papers 88
William Matsui
Livestrong Cancer Institutes, Dell Medical School, University of Texas at Austin
Co-authored papers 32
Linzhao Cheng
Johns Hopkins University School of Medicine
Co-authored papers 12
Zhaohui Ye
Center for Biologics Evaluation and Research
Co-authored papers 10
Alison R Moliterno
Johns Hopkins Hospital
Co-authored papers 9
Michelle Petri
Co-authored papers 9
Rong Hu
Co-authored papers 7
Mark J Levis
Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University
Co-authored papers 6
Neal S Young
National Heart Lung and Blood Institute Division of Intramural Research
Co-authored papers 5
Christopher D Gocke
Johns Hopkins University School of Medicine
Co-authored papers 5
Elizabeth Garrett-Mayer
Center for Research and Analytics, American Society of Clinical Oncology
Co-authored papers 4
Linda M S Resar
Johns Hopkins University School of Medicine
Co-authored papers 3
Guibin Chen
and Blood Institute, National Institutes of Health
Co-authored papers 3
David M Loeb
Children's Hospital at Montefiore.
Co-authored papers 3
Jizhong Zou
and Blood Institute, National Institutes of Health
Co-authored papers 3
Douglas A Kerr
Johns Hopkins University School of Medicine
Co-authored papers 3
Arthur J Vaught
Johns Hopkins Medicine
Co-authored papers 3
Cyndi F Liu
The Johns Hopkins University School of Medicine
Co-authored papers 3
Justin C McArthur
Johns Hopkins School of Medicine
Co-authored papers 2
Lisa R Yanek
Co-authored papers 2
Michael R DeBaun
Vanderbilt University School of Medicine
Co-authored papers 2
Sarah N Dowey
Johns Hopkins University School of Medicine, Institute for Cell Engineering
Co-authored papers 2
Jerry L Spivak
The Johns Hopkins University School of Medicine
Co-authored papers 2
Leslie G Biesecker
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 2
Prashant Mali (CM4AI)
University of California San Diego
Co-authored papers 2
Ada Hamosh
Johns Hopkins University School of Medicine
Co-authored papers 1
Athurva Gore
Co-authored papers 1
Ludmila Danilova
Bloomberg-Kimmel Immunotherapy Institute, Johns Hopkins University School of Medicine
Co-authored papers 1
Jennifer J Johnston
Center for Precision Health Research, National Human Genome Research Institute
Co-authored papers 1
Mai Nguyen
University of California Riverside
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Release 1.2