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Author Details
Full Name
Stephen P Jackson
Affiliation
Mission Therapeutics Ltd. Glenn Berge Building
ORCID
Career Start Year
1987
Papers
322
H Index
123
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36781955
Revolutionizing DNA repair research and cancer therapy with CRISPR-Cas screens.
Nat Rev Mol Cell Biol
2023
37601970
Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity.
Cell Genom
2023
38055822
RAD54L2 counters TOP2-DNA adducts to promote genome stability.
Sci Adv
2023
37957154
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.
Nat Commun
2023
37492888
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.
EMBO J
2023
36781955
Revolutionizing DNA repair research and cancer therapy with CRISPR-Cas screens.
Nat Rev Mol Cell Biol
2023
37957154
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson's disease mouse model.
Nat Commun
2023
38055822
RAD54L2 counters TOP2-DNA adducts to promote genome stability.
Sci Adv
2023
37601970
Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity.
Cell Genom
2023
37492888
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity.
EMBO J
2023
36121125
SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling.
EMBO J
2022
35764636
SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.
Nat Commun
2022
36121125
SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling.
EMBO J
2022
35764636
SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.
Nat Commun
2022
34329458
Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress.
Nucleic Acids Res
2021
33637726
Combinatorial CRISPR screen identifies fitness effects of gene paralogues.
Nat Commun
2021
33888558
Interfaces between cellular responses to DNA damage and cancer immunotherapy.
Genes Dev
2021
33764464
Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles.
Nucleic Acids Res
2021
34329458
Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress.
Nucleic Acids Res
2021
33764464
Mutagenic mechanisms of cancer-associated DNA polymerase ϵ alleles.
Nucleic Acids Res
2021
33637726
Combinatorial CRISPR screen identifies fitness effects of gene paralogues.
Nat Commun
2021
33888558
Interfaces between cellular responses to DNA damage and cancer immunotherapy.
Genes Dev
2021
32375023
CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure
2020
32375023
CCDC61/VFL3 Is a Paralog of SAS6 and Promotes Ciliary Functions.
Structure
2020
32042076
Chronic irradiation of human cells reduces histone levels and deregulates gene expression.
Sci Rep
2020
32041954
PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1.
Nat Commun
2020
32441252
Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance.
Elife
2020
32919786
The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease.
Kidney Int
2020
32918070
Author Correction: PGBD5 promotes site-specific oncogenic mutations in human tumors.
Nat Genet
2020
32968016
Trajectory and uniqueness of mutational signatures in yeast mutators.
Proc Natl Acad Sci U S A
2020
32042076
Chronic irradiation of human cells reduces histone levels and deregulates gene expression.
Sci Rep
2020
32041954
PALB2 chromatin recruitment restores homologous recombination in BRCA1-deficient cells depleted of 53BP1.
Nat Commun
2020
32919786
The phosphoinositide 3-kinase inhibitor alpelisib restores actin organization and improves proximal tubule dysfunction in vitro and in a mouse model of Lowe syndrome and Dent disease.
Kidney Int
2020
32918070
Author Correction: PGBD5 promotes site-specific oncogenic mutations in human tumors.
Nat Genet
2020
32968016
Trajectory and uniqueness of mutational signatures in yeast mutators.
Proc Natl Acad Sci U S A
2020
32441252
Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance.
Elife
2020
30622252
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.
Nat Commun
2019
31748747
Genetic predisposition to mosaic Y chromosome loss in blood.
Nature
2019
31729360
MDC1 PST-repeat region promotes histone H2AX-independent chromatin association and DNA damage tolerance.
Nat Commun
2019
30650353
Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia.
Cell Rep
2019
30622252
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.
Nat Commun
2019
31525021
Small-Molecule Inhibition of UBE2T/FANCL-Mediated Ubiquitylation in the Fanconi Anemia Pathway.
ACS Chem Biol
2019
31511699
Genome architecture and stability in the Saccharomyces cerevisiae knockout collection.
Nature
2019
30982602
A Compendium of Mutational Signatures of Environmental Agents.
Cell
2019
30976101
Retraction Note: KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling.
Nature
2019
30975768
Retraction.
Science
2019
31160788
Derivation and maintenance of mouse haploid embryonic stem cells.
Nat Protoc
2019
31729360
MDC1 PST-repeat region promotes histone H2AX-independent chromatin association and DNA damage tolerance.
Nat Commun
2019
31748747
Genetic predisposition to mosaic Y chromosome loss in blood.
Nature
2019
31525021
Small-Molecule Inhibition of UBE2T/FANCL-Mediated Ubiquitylation in the Fanconi Anemia Pathway.
ACS Chem Biol
2019
1 - 50 of 644
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