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Author Details

Fa-Xing Yu
Institute of Pediatrics, Children's Hospital of Fudan University
2008
59
31
PMIDPaper TitleJournal TitlePublished Year
36929007Phosphorylation of NF2 at Serine-13 by MAP4K family kinases mediates pathological angiogenesis.Protein Cell2023
37528078WWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT.Cell Death Dis2023
37647391TERT accelerates BRAF mutant-induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesis.Sci Adv2023
37684135Reconstructing the Hippo signaling network.Sci Bull (Beijing)2023
37350545Proteolytic activation of angiomotin by DDI2 promotes angiogenesis.EMBO J2023
36919851Two Hippo signaling modules orchestrate liver size and tumorigenesis.EMBO J2023
35292350Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis.J Hepatol2022
35429439WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy.Mol Cell2022
35455946Novel NPR2 Gene Mutations Affect Chondrocytes Function via ER Stress in Short Stature.Cells2022
36044856Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers.Cell Rep2022
34433060Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis.Cell Rep2021
33850002Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of <i>NF2</i>-deficient Mesothelioma.Mol Cancer Ther2021
33553074YAP Activation and Implications in Patients and a Mouse Model of Biliary Atresia.Front Pediatr2021
34874746STAT3-YAP/TAZ signaling in endothelial cells promotes tumor angiogenesis.Sci Signal2021
32773110Regulation of TP73 transcription by Hippo-YAP signaling.Biochem Biophys Res Commun2020
31748975USP47-mediated deubiquitination and stabilization of YAP contributes to the progression of colorectal cancer.Protein Cell2020
32069008Site-Selective Phosphoglycerate Mutase 1 Acetylation by a Small Molecule.ACS Chem Biol2020
32008206Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma.Protein Cell2020
33195240Hypermethylation of <i>LATS2</i> Promoter and Its Prognostic Value in <i>IDH</i>-Mutated Low-Grade Gliomas.Front Cell Dev Biol2020
32916277Nelfinavir inhibits human DDI2 and potentiates cytotoxicity of proteasome inhibitors.Cell Signal2020
30933975Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis.PLoS Biol2019
31072060GPCR-Hippo Signaling in Cancer.Cells2019
30979708An alternatively transcribed <i>TAZ</i> variant negatively regulates JAK-STAT signaling.EMBO Rep2019
31112131GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor.Elife2019
29562261Staurosporine targets the Hippo pathway to inhibit cell growth.J Mol Cell Biol2018
30135582RAP2 mediates mechanoresponses of the Hippo pathway.Nature2018
29400695Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.J Clin Invest2018
28757473Functions and regulations of the Hippo signaling pathway in intestinal homeostasis, regeneration and tumorigenesis.Yi Chuan2017
28130761The Hippo pathway in tissue homeostasis and regeneration.Protein Cell2017
26826652Oncogenic activation of the PI3K/Akt pathway promotes cellular glucose uptake by downregulating the expression of thioredoxin-interacting protein.Cell Signal2016
25195862Kaposi sarcoma-associated herpesvirus promotes tumorigenesis by modulating the Hippo pathway.Oncogene2015
26437443MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway.Nat Commun2015
26544935Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer.Cell2015
26276632Alternative Wnt Signaling Activates YAP/TAZ.Cell2015
26429069Targeting the Hippo Pathway for Anti-cancer Therapies.Curr Med Chem2015
26588989NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition.Genes Dev2015
26206313Opposing roles of conventional and novel PKC isoforms in Hippo-YAP pathway regulation.Cell Res2015
26109050A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis.Genes Dev2015
25893606Estrogen regulates Hippo signaling via GPER in breast cancer.J Clin Invest2015
25731159A gp130-Src-YAP module links inflammation to epithelial regeneration.Nature2015
25567907Metabolism. Differential regulation of mTORC1 by leucine and glutamine.Science2015
25293527Hippo pathway regulation of gastrointestinal tissues.Annu Rev Physiol2015
24639555Transcription and processing: multilayer controls of RNA biogenesis by the Hippo pathway.EMBO J2014
27308390YAP inhibition blocks uveal melanogenesis driven by GNAQ or GNA11 mutations.Mol Cell Oncol2014
25594048YAP as oncotarget in uveal melanoma.Oncoscience2014
24882516Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP.Cancer Cell2014
23431053The Hippo pathway: regulators and regulations.Genes Dev2013
23752589Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation.Genes Dev2013
22561086A potential mechanism of metformin-mediated regulation of glucose homeostasis: inhibition of Thioredoxin-interacting protein (Txnip) gene expression.Cell Signal2012
22972936Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs).Genes Dev2012
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Collaborators

Kun-Liang Guan
University of California San Diego
Co-authored papers 25
Zhipeng Meng
University of Miami Miller School of Medicine
Co-authored papers 9
Steven W Plouffe
University of California
Co-authored papers 7
Hyun Woo Park
College of Life Science and Biotechnology, Yonsei University
Co-authored papers 6
Audrey W Hong
Stanford University School of Medicine
Co-authored papers 4
Toshiro Moroishi
Kumamoto University
Co-authored papers 4
Cun-Yu Wang
University of California, Los Angeles (university of california los angeles)
Co-authored papers 3
Kang Zhang
College of Animal Science and Technology, Guangxi University
Co-authored papers 3
Susan S Taylor
University of California
Co-authored papers 2
Michael Karin
Co-authored papers 2
Koji Taniguchi
Co-authored papers 2
Hong Ouyang
Sun Yat-sen University
Co-authored papers 2
Kimberly C Lin
University of California san francisco
Co-authored papers 2
Shicong Lu
University of California San Diego
Co-authored papers 2
Ling Zhao
Sun Yat-sen University
Co-authored papers 1
Zhen Ye
Ludwig Institute for Cancer Research, University of California San Diego
Co-authored papers 1
Xiang-Dong Fu
Co-authored papers 1
Min Luo
Institute of Biomedical Science and Children's Hospital, Fudan University
Co-authored papers 1
Jorge Silvio Gutkind
Moores Cancer Center, University of California San Diego
Co-authored papers 1
Samuel B Ho
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences
Co-authored papers 1
Xiaoqiong Wang
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Aditya Kumar
Rice University, University of California San Diego
Co-authored papers 1
Fuchou Tang
College of Life Sciences
Co-authored papers 1
Brigid S Boland
University of California
Co-authored papers 1
Yarui Diao
Duke University Medical Center
Co-authored papers 1
Jesse K Placone
University of California San Diego
Co-authored papers 1
Bing Ren
Center for Epigenomics, University of California San Diego
Co-authored papers 1
Joan Heller Brown
Co-authored papers 1
Kuei-Chun Wang
Arizona State University
Co-authored papers 1
Margaret Pan
Basic Medical College, Anhui Medical University
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Release 1.2