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Author Details
Full Name
Michael C Wiener
Affiliation
University of Virginia
ORCID
Career Start Year
1986
Papers
55
H Index
33
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
32199981
Ste24: An Integral Membrane Protein Zinc Metalloprotease with Provocative Structure and Emergent Biology.
J Mol Biol
2020
31644822
The tripartite architecture of the eukaryotic integral membrane protein zinc metalloprotease Ste24.
Proteins
2020
30082509
Phosphoramidon inhibits the integral membrane protein zinc metalloprotease ZMPSTE24.
Acta Crystallogr D Struct Biol
2018
28119065
Acquisition of accurate data from intramolecular quenched fluorescence protease assays.
Anal Biochem
2017
27129777
Ste24p Mediates Proteolysis of Both Isoprenylated and Non-prenylated Oligopeptides.
J Biol Chem
2016
26175898
Integral membrane proteins and free electron lasers - a compatible couple indeed!
IUCrJ
2015
24739163
A critical evaluation of in silico methods for detection of membrane protein intrinsic disorder.
Biophys J
2014
23539602
Structure of the integral membrane protein CAAX protease Ste24p.
Science
2013
23381628
Coordinating the impact of structural genomics on the human α-helical transmembrane proteome.
Nat Struct Mol Biol
2013
21693645
How hydrophobic molecules traverse the outer membranes of gram-negative bacteria.
Proc Natl Acad Sci U S A
2011
21539919
The variable detergent sensitivity of proteases that are utilized for recombinant protein affinity tag removal.
Protein Expr Purif
2011
20153331
Design and characterization of a constitutively open KcsA.
FEBS Lett
2010
20816073
Conformational exchange in a membrane transport protein is altered in protein crystals.
Biophys J
2010
20667442
A high-throughput differential filtration assay to screen and select detergents for membrane proteins.
Anal Biochem
2010
19747487
Coupling of calcium and substrate binding through loop alignment in the outer-membrane transporter BtuB.
J Mol Biol
2009
17449669
Mechanics of force propagation in TonB-dependent outer membrane transport.
Biophys J
2007
16741124
Outer membrane active transport: structure of the BtuB:TonB complex.
Science
2006
17132858
When worlds colloid.
Protein Sci
2006
16820681
Crystallization and preliminary X-ray crystallographic analysis of the Escherichia coli outer membrane cobalamin transporter BtuB in complex with the carboxy-terminal domain of TonB.
Acta Crystallogr Sect F Struct Biol Cryst Commun
2006
15739205
Comparative structural analysis of TonB-dependent outer membrane transporters: implications for the transport cycle.
Proteins
2005
16039843
TonB-dependent outer membrane transport: going for Baroque?
Curr Opin Struct Biol
2005
14711520
Membrane protein expression and production: effects of polyhistidine tag length and position.
Protein Expr Purif
2004
15325654
A pedestrian guide to membrane protein crystallization.
Methods
2004
12509992
Inhibition of tobacco etch virus protease activity by detergents.
Protein Expr Purif
2003
14499604
The Escherichia coli outer membrane cobalamin transporter BtuB: structural analysis of calcium and substrate binding, and identification of orthologous transporters by sequence/structure conservation.
J Mol Biol
2003
12902336
Enzymatic E-colicins bind to their target receptor BtuB by presentation of a small binding epitope on a coiled-coil scaffold.
J Biol Chem
2003
14528295
The structure of BtuB with bound colicin E3 R-domain implies a translocon.
Nat Struct Biol
2003
12652322
Substrate-induced transmembrane signaling in the cobalamin transporter BtuB.
Nat Struct Biol
2003
12595710
Crystallization and initial X-ray diffraction of BtuB, the integral membrane cobalamin transporter of Escherichia coli.
Acta Crystallogr D Biol Crystallogr
2003
11790740
Identification of the periplasmic cobalamin-binding protein BtuF of Escherichia coli.
J Bacteriol
2002
12077430
Thiol-reactive lanthanide chelates for phasing protein X-ray diffraction data.
Acta Crystallogr D Biol Crystallogr
2002
10648805
Expression, purification, and initial structural characterization of YadQ, a bacterial homolog of mammalian ClC chloride channel proteins.
FEBS Lett
2000
10986468
Bacterial export takes its Tol.
Structure
2000
10933509
Mesoscopic surfactant organization and membrane protein crystallization.
Protein Sci
2000
10548052
Outer membrane protein A of E. coli folds into detergent micelles, but not in the presence of monomeric detergent.
Protein Sci
1999
9729746
Ion-channel-forming colicins.
Curr Opin Struct Biol
1998
9009197
Crystal structure of colicin Ia.
Nature
1997
8921199
A lectin screening method for membrane glycoproteins: application to the human CHIP28 water channel (AQP-1).
Anal Biochem
1996
7532004
Purification and structure-function analysis of native, PNGase F-treated, and endo-beta-galactosidase-treated CHIP28 water channels.
Biochemistry
1995
7552739
The CHIP28 water channel visualized in ice by electron crystallography.
Nat Struct Biol
1995
7524655
Projection structure of the CHIP28 water channel in lipid bilayer membranes at 12-A resolution.
Biochemistry
1994
8218256
Secondary structure analysis of purified functional CHIP28 water channels by CD and FTIR spectroscopy.
Biochemistry
1993
1547330
Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. II. Distribution and packing of terminal methyl groups.
Biophys J
1992
1547331
Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. III. Complete structure.
Biophys J
1992
2069956
Transbilayer distribution of bromine in fluid bilayers containing a specifically brominated analogue of dioleoylphosphatidylcholine.
Biochemistry
1991
1932548
Structure of a fluid dioleoylphosphatidylcholine bilayer determined by joint refinement of x-ray and neutron diffraction data. I. Scaling of neutron data and the distributions of double bonds and water.
Biophys J
1991
2015381
Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. I. Fluid bilayer models and the limits of resolution.
Biophys J
1991
2015382
Fluid bilayer structure determination by the combined use of x-ray and neutron diffraction. II. "Composition-space" refinement method.
Biophys J
1991
2713444
Relations for lipid bilayers. Connection of electron density profiles to other structural quantities.
Biophys J
1989
2713445
Structure of the fully hydrated gel phase of dipalmitoylphosphatidylcholine.
Biophys J
1989
1 - 50 of 55
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row(s) 1 - 30 of 30
Collaborators
Stephen H White
Co-authored papers
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Robert M Stroud
University of California San Francisco
Co-authored papers
4
Michael G Malkowski
Jacobs School of Medicine and Biomedical Sciences, University of Buffalo
Co-authored papers
2
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University of Illinois at Urbana-Champaign
Co-authored papers
2
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University of Rochester Medical Center
Co-authored papers
2
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Georgia Institute of Technology
Co-authored papers
2
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University of California San Francisco
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University of California
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1
Burkhard Rost
Technical University of Munich (TUM)
Co-authored papers
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Raymond C Stevens
iHuman Institute, ShanghaiTech University
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Wayne A Hendrickson
Columbia University
Co-authored papers
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Harvard Medical School
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University of California San Francisco
Co-authored papers
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Michael H B Stowell
University of Colorado Boulder
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Howard Hughes Medical Institute, California Institute of Technology
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Avner Schlessinger
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers
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Geoffrey Chang
Skaggs School of Pharmacy and Pharmaceutical Sciences.
Co-authored papers
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David L Stokes
NYU School of Medicine
Co-authored papers
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Institute for Advanced Study (TUM-IAS), TUM (Technische Universitat Munchen)
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